Synergistic in vitro interactions between (22S,23S)-3β-bromo-5α, 22,23-trihydroxystigmastan-6-one and acyclovir or foscarnet against herpes simplex virus type 1

The replication of herpes simplex virus (HSV) type 1 in Vero cells is inhibited in the presence of (22S,23S)-3β-bromo-5α,22,23- trihydroxystigmastan-6-one (6b), a synthetic brassinosteroid derivative. Since a late step of virus multiplication is hindered by 6b, we performed studies of drug-drug comb...

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Detalles Bibliográficos
Autores principales: Talarico, Laura Beatriz, Castilla, Viviana, Ramirez, Javier Alberto, Wachsman, Mónica Beatriz
Publicado: 2005
Materias:
(22S,23S)-3β-bromo- 5α,22,23-trihydroxystigmastan-6-one
Antiviral drug-drug combinations
Brassinosteroid derivatives
Herpes simplex
3beta bromo 5alpha,22,23 trihydroxystigmastan 6 one
aciclovir
antivirus agent
foscarnet
unclassified drug
antiviral activity
article
controlled study
DNA sequence
drug activity
drug potentiation
gene frequency
gene mutation
gene targeting
Herpes simplex virus
nonhuman
priority journal
protein phosphorylation
virogenesis
Acyclovir
Animals
Antiviral Agents
Cell Line
Cell Proliferation
Cercopithecus aethiops
Cholestanones
Drug Synergism
Foscarnet
Herpesvirus 1, Human
Molecular Structure
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00093157_v52_n1_p38_Talarico
http://hdl.handle.net/20.500.12110/paper_00093157_v52_n1_p38_Talarico
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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