Facile synthesis of methyl α- and β-d-[6-3H]galactofuranosides from d-galacturonic acid. Substrates for the detection of galactofuranosidases
Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl α,β-d-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiola...
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2008
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v343_n10-11_p1863_Bordoni http://hdl.handle.net/20.500.12110/paper_00086215_v343_n10-11_p1863_Bordoni |
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paper:paper_00086215_v343_n10-11_p1863_Bordoni2023-06-08T14:32:54Z Facile synthesis of methyl α- and β-d-[6-3H]galactofuranosides from d-galacturonic acid. Substrates for the detection of galactofuranosidases Bordoni, Andrea Verónica Mariño, Karina V. Muchnik de Lederkremer, Rosa María Marino, María Carla d-Galacturonic acid Galactofuranosidases Galactofuranosides Methyl glycofuranosides Penicillium varians Carboxylic acids Chemotherapy Microorganisms Reduction Synthesis (chemical) Galactofuranosidases Galactofuranosides Methyl glycofuranosides Penicillium varians Radiolabeled substrates Aromatic compounds carbohydrate derivative galactofuranosidase derivative galacturonic acid methyl alpha galactofuranoside 6 h 3 methyl beta galactofuranoside 6 h 3 article carbohydrate metabolism glycosylation isotope labeling priority journal synthesis Furans Glycoside Hydrolases Hexuronic Acids Isotope Labeling Methylgalactosides Stereoisomerism Tritium Penicillium Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl α,β-d-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. © 2008 Elsevier Ltd. All rights reserved. Fil:Bordoni, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Mariño, K. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:de Lederkremer, R.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Marino, C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2008 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v343_n10-11_p1863_Bordoni http://hdl.handle.net/20.500.12110/paper_00086215_v343_n10-11_p1863_Bordoni |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
d-Galacturonic acid Galactofuranosidases Galactofuranosides Methyl glycofuranosides Penicillium varians Carboxylic acids Chemotherapy Microorganisms Reduction Synthesis (chemical) Galactofuranosidases Galactofuranosides Methyl glycofuranosides Penicillium varians Radiolabeled substrates Aromatic compounds carbohydrate derivative galactofuranosidase derivative galacturonic acid methyl alpha galactofuranoside 6 h 3 methyl beta galactofuranoside 6 h 3 article carbohydrate metabolism glycosylation isotope labeling priority journal synthesis Furans Glycoside Hydrolases Hexuronic Acids Isotope Labeling Methylgalactosides Stereoisomerism Tritium Penicillium |
| spellingShingle |
d-Galacturonic acid Galactofuranosidases Galactofuranosides Methyl glycofuranosides Penicillium varians Carboxylic acids Chemotherapy Microorganisms Reduction Synthesis (chemical) Galactofuranosidases Galactofuranosides Methyl glycofuranosides Penicillium varians Radiolabeled substrates Aromatic compounds carbohydrate derivative galactofuranosidase derivative galacturonic acid methyl alpha galactofuranoside 6 h 3 methyl beta galactofuranoside 6 h 3 article carbohydrate metabolism glycosylation isotope labeling priority journal synthesis Furans Glycoside Hydrolases Hexuronic Acids Isotope Labeling Methylgalactosides Stereoisomerism Tritium Penicillium Bordoni, Andrea Verónica Mariño, Karina V. Muchnik de Lederkremer, Rosa María Marino, María Carla Facile synthesis of methyl α- and β-d-[6-3H]galactofuranosides from d-galacturonic acid. Substrates for the detection of galactofuranosidases |
| topic_facet |
d-Galacturonic acid Galactofuranosidases Galactofuranosides Methyl glycofuranosides Penicillium varians Carboxylic acids Chemotherapy Microorganisms Reduction Synthesis (chemical) Galactofuranosidases Galactofuranosides Methyl glycofuranosides Penicillium varians Radiolabeled substrates Aromatic compounds carbohydrate derivative galactofuranosidase derivative galacturonic acid methyl alpha galactofuranoside 6 h 3 methyl beta galactofuranoside 6 h 3 article carbohydrate metabolism glycosylation isotope labeling priority journal synthesis Furans Glycoside Hydrolases Hexuronic Acids Isotope Labeling Methylgalactosides Stereoisomerism Tritium Penicillium |
| description |
Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl α,β-d-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. © 2008 Elsevier Ltd. All rights reserved. |
| author |
Bordoni, Andrea Verónica Mariño, Karina V. Muchnik de Lederkremer, Rosa María Marino, María Carla |
| author_facet |
Bordoni, Andrea Verónica Mariño, Karina V. Muchnik de Lederkremer, Rosa María Marino, María Carla |
| author_sort |
Bordoni, Andrea Verónica |
| title |
Facile synthesis of methyl α- and β-d-[6-3H]galactofuranosides from d-galacturonic acid. Substrates for the detection of galactofuranosidases |
| title_short |
Facile synthesis of methyl α- and β-d-[6-3H]galactofuranosides from d-galacturonic acid. Substrates for the detection of galactofuranosidases |
| title_full |
Facile synthesis of methyl α- and β-d-[6-3H]galactofuranosides from d-galacturonic acid. Substrates for the detection of galactofuranosidases |
| title_fullStr |
Facile synthesis of methyl α- and β-d-[6-3H]galactofuranosides from d-galacturonic acid. Substrates for the detection of galactofuranosidases |
| title_full_unstemmed |
Facile synthesis of methyl α- and β-d-[6-3H]galactofuranosides from d-galacturonic acid. Substrates for the detection of galactofuranosidases |
| title_sort |
facile synthesis of methyl α- and β-d-[6-3h]galactofuranosides from d-galacturonic acid. substrates for the detection of galactofuranosidases |
| publishDate |
2008 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v343_n10-11_p1863_Bordoni http://hdl.handle.net/20.500.12110/paper_00086215_v343_n10-11_p1863_Bordoni |
| work_keys_str_mv |
AT bordoniandreaveronica facilesynthesisofmethylaandbd63hgalactofuranosidesfromdgalacturonicacidsubstratesforthedetectionofgalactofuranosidases AT marinokarinav facilesynthesisofmethylaandbd63hgalactofuranosidesfromdgalacturonicacidsubstratesforthedetectionofgalactofuranosidases AT muchnikdelederkremerrosamaria facilesynthesisofmethylaandbd63hgalactofuranosidesfromdgalacturonicacidsubstratesforthedetectionofgalactofuranosidases AT marinomariacarla facilesynthesisofmethylaandbd63hgalactofuranosidesfromdgalacturonicacidsubstratesforthedetectionofgalactofuranosidases |
| _version_ |
1768546424864112640 |