Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides

Several commercial sulfated neocarrabiose oligosaccharides were analyzed by matrix-assisted ultraviolet laser-desorption ionization time-of-flight mass spectrometry (UV-MALDI-TOF-MS). UV-MALDI-TOF-MS was carried out in the linear and reflectron modes and, as routine, in both the positive- and negati...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ciancia, Marina, Cerezo, Alberto Saúl, Erra Balsells, Rosa, Matulewicz, María Cristina
Publicado:	2002
Materias:	ESI-TOF-MS kappa-Carrageenan oligosaccharides PSD UV-MALDI-TOF-MS Sulfated neocarrabiose oligosaccharides Sulfated oligosaccharides UV-MALDI-TOF-MS Carboxylic acids Ionization Mass spectrometry Ultraviolet radiation Fragmentation Oligomers gentisic acid harman neocarrabiose 4 sulfate neocarradodecaose 4,4,4,4,4,4 hexasulfate neocarrahexaose 2,4,4,4 tetrasulfate neocarrahexaose 4,4,4 trisulfate neocarraoctaose 4,4,4,4 tetrasulfate neocarratetraose 4 sulfate neocarratetraose 4,4 disulfate oligosaccharide unclassified drug analytic method article carbohydrate analysis chemical bond desorption ionization matrix assisted laser desorption ionization time of flight mass spectrometry priority journal sulfation Carbohydrate Sequence Carrageenan Molecular Sequence Data Oligosaccharides Spectrometry, Mass, Electrospray Ionization Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sulfates Ultraviolet Rays
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v337_n17_p1553_Fukuyama http://hdl.handle.net/20.500.12110/paper_00086215_v337_n17_p1553_Fukuyama
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00086215_v337_n17_p1553_Fukuyama
record_format	dspace
spelling	paper:paper_00086215_v337_n17_p1553_Fukuyama2023-06-08T14:32:41Z Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides Ciancia, Marina Cerezo, Alberto Saúl Erra Balsells, Rosa Matulewicz, María Cristina ESI-TOF-MS kappa-Carrageenan oligosaccharides PSD UV-MALDI-TOF-MS Sulfated neocarrabiose oligosaccharides Sulfated oligosaccharides UV-MALDI-TOF-MS Carboxylic acids Ionization Mass spectrometry Ultraviolet radiation Fragmentation Oligomers gentisic acid harman neocarrabiose 4 sulfate neocarradodecaose 4,4,4,4,4,4 hexasulfate neocarrahexaose 2,4,4,4 tetrasulfate neocarrahexaose 4,4,4 trisulfate neocarraoctaose 4,4,4,4 tetrasulfate neocarratetraose 4 sulfate neocarratetraose 4,4 disulfate oligosaccharide unclassified drug analytic method article carbohydrate analysis chemical bond desorption ionization matrix assisted laser desorption ionization time of flight mass spectrometry priority journal sulfation Carbohydrate Sequence Carrageenan Molecular Sequence Data Oligosaccharides Spectrometry, Mass, Electrospray Ionization Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sulfates Ultraviolet Rays Several commercial sulfated neocarrabiose oligosaccharides were analyzed by matrix-assisted ultraviolet laser-desorption ionization time-of-flight mass spectrometry (UV-MALDI-TOF-MS). UV-MALDI-TOF-MS was carried out in the linear and reflectron modes and, as routine, in both the positive- and negative-ion modes. 2,5-Dihydroxybenzoic acid and nor-harmane were used as matrices. In the positive- and negative-ion modes, with both matrices, peaks corresponding to (M+Na)+ and (M-Na)- ions, respectively, were obtained, with only some signals due to glycosidic linkage cleavages (prompt fragmentation). With 2,5-dihydroxybenzoic acid abundant matrix signals were observed; nor-harmane afforded very few matrix signals in both ion modes, but more desulfation (prompt fragmentation) of the compounds occurred. When the desorption/ionization process was highly efficient, the post-source decay (PSD) fragmentation patterns were also investigated; most of the fragments detected derived from glycosidic linkage cleavages. Electrospray-ionization time-of-flight mass spectrometry (ESI-TOF-MS) in the negative-ion mode confirmed, with the observation of the (M-Na)- and the multiply charged anions, the identity and the purity of the samples. © 2002 Elsevier Science Ltd. All rights reserved. Fil:Ciancia, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Cerezo, A.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Erra-Balsells, R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Matulewicz, M.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2002 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v337_n17_p1553_Fukuyama http://hdl.handle.net/20.500.12110/paper_00086215_v337_n17_p1553_Fukuyama
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	ESI-TOF-MS kappa-Carrageenan oligosaccharides PSD UV-MALDI-TOF-MS Sulfated neocarrabiose oligosaccharides Sulfated oligosaccharides UV-MALDI-TOF-MS Carboxylic acids Ionization Mass spectrometry Ultraviolet radiation Fragmentation Oligomers gentisic acid harman neocarrabiose 4 sulfate neocarradodecaose 4,4,4,4,4,4 hexasulfate neocarrahexaose 2,4,4,4 tetrasulfate neocarrahexaose 4,4,4 trisulfate neocarraoctaose 4,4,4,4 tetrasulfate neocarratetraose 4 sulfate neocarratetraose 4,4 disulfate oligosaccharide unclassified drug analytic method article carbohydrate analysis chemical bond desorption ionization matrix assisted laser desorption ionization time of flight mass spectrometry priority journal sulfation Carbohydrate Sequence Carrageenan Molecular Sequence Data Oligosaccharides Spectrometry, Mass, Electrospray Ionization Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sulfates Ultraviolet Rays
spellingShingle	ESI-TOF-MS kappa-Carrageenan oligosaccharides PSD UV-MALDI-TOF-MS Sulfated neocarrabiose oligosaccharides Sulfated oligosaccharides UV-MALDI-TOF-MS Carboxylic acids Ionization Mass spectrometry Ultraviolet radiation Fragmentation Oligomers gentisic acid harman neocarrabiose 4 sulfate neocarradodecaose 4,4,4,4,4,4 hexasulfate neocarrahexaose 2,4,4,4 tetrasulfate neocarrahexaose 4,4,4 trisulfate neocarraoctaose 4,4,4,4 tetrasulfate neocarratetraose 4 sulfate neocarratetraose 4,4 disulfate oligosaccharide unclassified drug analytic method article carbohydrate analysis chemical bond desorption ionization matrix assisted laser desorption ionization time of flight mass spectrometry priority journal sulfation Carbohydrate Sequence Carrageenan Molecular Sequence Data Oligosaccharides Spectrometry, Mass, Electrospray Ionization Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sulfates Ultraviolet Rays Ciancia, Marina Cerezo, Alberto Saúl Erra Balsells, Rosa Matulewicz, María Cristina Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides
topic_facet	ESI-TOF-MS kappa-Carrageenan oligosaccharides PSD UV-MALDI-TOF-MS Sulfated neocarrabiose oligosaccharides Sulfated oligosaccharides UV-MALDI-TOF-MS Carboxylic acids Ionization Mass spectrometry Ultraviolet radiation Fragmentation Oligomers gentisic acid harman neocarrabiose 4 sulfate neocarradodecaose 4,4,4,4,4,4 hexasulfate neocarrahexaose 2,4,4,4 tetrasulfate neocarrahexaose 4,4,4 trisulfate neocarraoctaose 4,4,4,4 tetrasulfate neocarratetraose 4 sulfate neocarratetraose 4,4 disulfate oligosaccharide unclassified drug analytic method article carbohydrate analysis chemical bond desorption ionization matrix assisted laser desorption ionization time of flight mass spectrometry priority journal sulfation Carbohydrate Sequence Carrageenan Molecular Sequence Data Oligosaccharides Spectrometry, Mass, Electrospray Ionization Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sulfates Ultraviolet Rays
description	Several commercial sulfated neocarrabiose oligosaccharides were analyzed by matrix-assisted ultraviolet laser-desorption ionization time-of-flight mass spectrometry (UV-MALDI-TOF-MS). UV-MALDI-TOF-MS was carried out in the linear and reflectron modes and, as routine, in both the positive- and negative-ion modes. 2,5-Dihydroxybenzoic acid and nor-harmane were used as matrices. In the positive- and negative-ion modes, with both matrices, peaks corresponding to (M+Na)+ and (M-Na)- ions, respectively, were obtained, with only some signals due to glycosidic linkage cleavages (prompt fragmentation). With 2,5-dihydroxybenzoic acid abundant matrix signals were observed; nor-harmane afforded very few matrix signals in both ion modes, but more desulfation (prompt fragmentation) of the compounds occurred. When the desorption/ionization process was highly efficient, the post-source decay (PSD) fragmentation patterns were also investigated; most of the fragments detected derived from glycosidic linkage cleavages. Electrospray-ionization time-of-flight mass spectrometry (ESI-TOF-MS) in the negative-ion mode confirmed, with the observation of the (M-Na)- and the multiply charged anions, the identity and the purity of the samples. © 2002 Elsevier Science Ltd. All rights reserved.
author	Ciancia, Marina Cerezo, Alberto Saúl Erra Balsells, Rosa Matulewicz, María Cristina
author_facet	Ciancia, Marina Cerezo, Alberto Saúl Erra Balsells, Rosa Matulewicz, María Cristina
author_sort	Ciancia, Marina
title	Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides
title_short	Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides
title_full	Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides
title_fullStr	Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides
title_full_unstemmed	Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides
title_sort	matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides
publishDate	2002
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v337_n17_p1553_Fukuyama http://hdl.handle.net/20.500.12110/paper_00086215_v337_n17_p1553_Fukuyama
work_keys_str_mv	AT cianciamarina matrixassistedultravioletlaserdesorptionionizationandelectrosprayionizationtimeofflightmassspectrometryofsulfatedneocarrabioseoligosaccharides AT cerezoalbertosaul matrixassistedultravioletlaserdesorptionionizationandelectrosprayionizationtimeofflightmassspectrometryofsulfatedneocarrabioseoligosaccharides AT errabalsellsrosa matrixassistedultravioletlaserdesorptionionizationandelectrosprayionizationtimeofflightmassspectrometryofsulfatedneocarrabioseoligosaccharides AT matulewiczmariacristina matrixassistedultravioletlaserdesorptionionizationandelectrosprayionizationtimeofflightmassspectrometryofsulfatedneocarrabioseoligosaccharides
_version_	1768545216045776896

Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides

Ejemplares similares