Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802)
Toxicity parameters of Copper to pre-metamorphic larvae of Lithobates catesbeianus were evaluated in laboratory conditions. The acute toxicity (as LC-50 96 h) was 3.96 mg Cu 2+ L -1 (95% confidence interval: 3.21-4.89); the bioconcentration of the metal after 96 h exposure followed an exponential in...
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00074861_v84_n6_p712_Ossana http://hdl.handle.net/20.500.12110/paper_00074861_v84_n6_p712_Ossana |
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paper:paper_00074861_v84_n6_p712_Ossana2023-06-08T14:31:47Z Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802) Ossana, Natalia Alejandra Poletta, Gisela Laura Mudry, Marta Dolores Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Bioconcentration Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity Copper copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Animals Copper Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates Toxicity parameters of Copper to pre-metamorphic larvae of Lithobates catesbeianus were evaluated in laboratory conditions. The acute toxicity (as LC-50 96 h) was 3.96 mg Cu 2+ L -1 (95% confidence interval: 3.21-4.89); the bioconcentration of the metal after 96 h exposure followed an exponential increase. The potential genotoxicity effect evaluated with Micronucleus Test showed a reduced sensitivity of the animals to the assayed concentrations of the metal, exhibiting only a modest increase in the frequency of erythrocytes micronuclei, meanwhile larvae exposed to cyclophosphamide (positive control) showed significant increases. The Condition Factor was significantly reduced while the Hepatosomatic Index remained unaltered. © 2010 Springer Science+Business Media, LLC. Fil:Ossana, N.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Poletta, G.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Mudry, M.D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2010 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00074861_v84_n6_p712_Ossana http://hdl.handle.net/20.500.12110/paper_00074861_v84_n6_p712_Ossana |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Bioconcentration Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity Copper copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Animals Copper Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates |
spellingShingle |
Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Bioconcentration Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity Copper copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Animals Copper Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates Ossana, Natalia Alejandra Poletta, Gisela Laura Mudry, Marta Dolores Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802) |
topic_facet |
Bioconcentration Copper Genotoxicity Lithobates catesbeianus tadpole Acute toxicity Bioconcentration Confidence interval Exponential increase Genotoxicities Hepatosomatic indices Laboratory conditions Micronucleus test Reduced sensitivity Animals Toxicity Copper copper animal article chemically induced disorder drug effect erythrocyte frog growth, development and aging larva LD 50 metabolism metamorphosis micronucleus micronucleus test toxicity testing water pollutant Acute Toxicity Tests Animals Copper Erythrocytes Larva Lethal Dose 50 Metamorphosis, Biological Micronuclei, Chromosome-Defective Micronucleus Tests Ranidae Water Pollutants, Chemical Animalia Lithobates |
description |
Toxicity parameters of Copper to pre-metamorphic larvae of Lithobates catesbeianus were evaluated in laboratory conditions. The acute toxicity (as LC-50 96 h) was 3.96 mg Cu 2+ L -1 (95% confidence interval: 3.21-4.89); the bioconcentration of the metal after 96 h exposure followed an exponential increase. The potential genotoxicity effect evaluated with Micronucleus Test showed a reduced sensitivity of the animals to the assayed concentrations of the metal, exhibiting only a modest increase in the frequency of erythrocytes micronuclei, meanwhile larvae exposed to cyclophosphamide (positive control) showed significant increases. The Condition Factor was significantly reduced while the Hepatosomatic Index remained unaltered. © 2010 Springer Science+Business Media, LLC. |
author |
Ossana, Natalia Alejandra Poletta, Gisela Laura Mudry, Marta Dolores |
author_facet |
Ossana, Natalia Alejandra Poletta, Gisela Laura Mudry, Marta Dolores |
author_sort |
Ossana, Natalia Alejandra |
title |
Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802) |
title_short |
Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802) |
title_full |
Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802) |
title_fullStr |
Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802) |
title_full_unstemmed |
Toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (Shaw, 1802) |
title_sort |
toxicity of waterborne copper in premetamorphic tadpoles of lithobates catesbeianus (shaw, 1802) |
publishDate |
2010 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00074861_v84_n6_p712_Ossana http://hdl.handle.net/20.500.12110/paper_00074861_v84_n6_p712_Ossana |
work_keys_str_mv |
AT ossananataliaalejandra toxicityofwaterbornecopperinpremetamorphictadpolesoflithobatescatesbeianusshaw1802 AT polettagiselalaura toxicityofwaterbornecopperinpremetamorphictadpolesoflithobatescatesbeianusshaw1802 AT mudrymartadolores toxicityofwaterbornecopperinpremetamorphictadpolesoflithobatescatesbeianusshaw1802 |
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1768541545175187456 |