Health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review
Fil: Miranda, Rafael N. University Health Network; Canadá.
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| Formato: | Artículo publishedVersion |
| Lenguaje: | Inglés |
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Elsevier
2020
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| Acceso en línea: | https://hdl.handle.net/20.500.12219/5077 |
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I77-R195-20.500.12219-5077 |
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I77-R195-20.500.12219-50772024-06-04T12:56:48Z Health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review Miranda, Rafael N. Ximenes, Raphael Gebretekle, Gebremedhin B. Bielecki, Joanna M. Sander, Beate Guillain Barré syndrome Microcephaly Zika virus Health-related quality of life Systematic review Fil: Miranda, Rafael N. University Health Network; Canadá. Fil: Ximenes, Raphael. University Health Network; Canadá. Fil: Gebretekle, Gebremedhin B. University Health Network; Canadá. Fil: Bielecki, Joanna M. University Health Network; Canadá. Fil: Sander, Beate. University Health Network; Canadá. Objectives: In this systematic review, we synthesize the current evidence on health-related quality of life (HRQoL) for the two of the most relevant outcomes of Zika virus infection in humans, microcephaly and Guillain-Barré Syndrome (GBS). Methods: We searched the following databases: MEDLINE, Embase, CINAHL, LILACS, WHO’s ICTRP clinical trials registries database and PROSPERO. Search terms included quality of life, microcephaly, and Guillain-Barré Syndrome. We included primary studies where HRQoL was quantitatively assessed for microcephaly and GBS using validated instruments. We used the Joanna Briggs Institute Critical Appraisal Tools to assess the risk of bias of individual studies. Results: From a total of 1,657 abstracts screened and 66 full texts reviewed, 21 studies met the eligibility criteria; one study for microcephaly and 20 for GBS. Adjusted disutilities for microcephaly compared to a normative childhood utility ranged from 20.745 to 20.820. For GBS, time traded-off the expected lifetime ranged from 16 days to 3 years. HRQoL follows the clinical course of GBS, with lower scores in the first months, recovery within the first year post onset, and stabilization after one year. Conclusions: Included studies reported a wide range of HRQoL for GBS, due in part to a high level of heterogeneity in methods, inclusion criteria, follow-up and reporting of results. Opportunities exist for primary studies assessing the longitudinal HRQoL over the entire course of the diseases to inform clinical practice, economic evaluations and health policy. 2020-07-01 info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion https://hdl.handle.net/20.500.12219/5077 eng info:eu-repo/semantics/altIdentifier/urn/https://www.sciencedirect.com/science/article/pii/S1098301520301807 info:eu-repo/semantics/altIdentifier/urn/https://www.valueinhealthjournal.com/article/S1098-3015(20)30180-7/fulltext?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1098301520301807%3Fshowall%3Dtrue info:eu-repo/semantics/openAccess application/pdf application/pdf 1.1 MB Elsevier |
| institution |
Universidad Nacional de Misiones |
| institution_str |
I-77 |
| repository_str |
R-195 |
| collection |
Repositorio Institucional Digital de la UNaM (RIDUNAM) |
| language |
Inglés |
| topic |
Guillain Barré syndrome Microcephaly Zika virus Health-related quality of life Systematic review |
| spellingShingle |
Guillain Barré syndrome Microcephaly Zika virus Health-related quality of life Systematic review Miranda, Rafael N. Ximenes, Raphael Gebretekle, Gebremedhin B. Bielecki, Joanna M. Sander, Beate Health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review |
| topic_facet |
Guillain Barré syndrome Microcephaly Zika virus Health-related quality of life Systematic review |
| description |
Fil: Miranda, Rafael N. University Health Network; Canadá. |
| format |
Artículo Artículo publishedVersion |
| author |
Miranda, Rafael N. Ximenes, Raphael Gebretekle, Gebremedhin B. Bielecki, Joanna M. Sander, Beate |
| author_facet |
Miranda, Rafael N. Ximenes, Raphael Gebretekle, Gebremedhin B. Bielecki, Joanna M. Sander, Beate |
| author_sort |
Miranda, Rafael N. |
| title |
Health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review |
| title_short |
Health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review |
| title_full |
Health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review |
| title_fullStr |
Health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review |
| title_full_unstemmed |
Health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review |
| title_sort |
health-related quality of life in neurological disorders most commonly associated with zika-virus infection : a systematic review |
| publisher |
Elsevier |
| publishDate |
2020 |
| url |
https://hdl.handle.net/20.500.12219/5077 |
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1809776477820944384 |