Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines

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ARTÍCULO PUBLICADO EN REVISTA EXTERNA. External antiparasitic agents applied in bovine production represent a risk to consumers of meat products, espe- cially if the conditions of their use are not strictly respected. The post-mortem control of residues in meat is an activity that must be update...

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Autores principales: Ferré, Daniela Marisol, Jotallan, Paola, Lentini, Valeria, Ludueña, Héctor Ricardo, Romano, Raquel, Gorla, Nora Bibiana María
Formato: Artículo Científico
Lenguaje:Inglés
Publicado: Science of the Total Environment Editorial 2021
Materias:
Pre-slaughter controls
Antiparasitic
Cytokinesis-block micronucleus cytome assay
Cholinesterases
Cattle
Biomarkers
Acceso en línea:http://repositorio.umaza.edu.ar//handle/00261/2370
Aporte de:
UMAZA Digital (Universidad MAZA - Mendoza) de Universidad Juan Agustín MAZA
id I56-R16200261-2370
record_format dspace
institution Universidad Juan Agustín MAZA
institution_str I-56
repository_str R-162
collection UMAZA Digital (Universidad MAZA - Mendoza)
language Inglés
orig_language_str_mv eng
topic Pre-slaughter controls
Antiparasitic
Cytokinesis-block micronucleus cytome assay
Cholinesterases
Cattle
Biomarkers
spellingShingle Pre-slaughter controls
Antiparasitic
Cytokinesis-block micronucleus cytome assay
Cholinesterases
Cattle
Biomarkers
Ferré, Daniela Marisol
Jotallan, Paola
Lentini, Valeria
Ludueña, Héctor Ricardo
Romano, Raquel
Gorla, Nora Bibiana María
Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines
description ARTÍCULO PUBLICADO EN REVISTA EXTERNA. External antiparasitic agents applied in bovine production represent a risk to consumers of meat products, espe- cially if the conditions of their use are not strictly respected. The post-mortem control of residues in meat is an activity that must be updated and reinforced by the biomonitoring of live animals and the use of analytical tools to help identifying signs of early warning risks. The objective of the present study was to carry out a pre- slaughter biomonitoring approach in Aberdeen Angus cattle and crosses (n = 12) with the application of a com- mercial formulation of cypermethrin plus chlorpyrifos. This was performed with a single therapeutic dose ap- plied on the backs of the cattle, through hematological, enzymatic, as well as hepatic and renal function analysis in plasma, and then quantifying the genotoxic effect on lymphocytes. Analytical measurements of plasma concentrations of cypermethrin plus chlorpyrifos at 24 h were negative and therefore a low absorption of the compounds was assumed. Measurement of acetyl cholinesterase showed no inhibition after exposure. The concentration of urea increased between 24 h and 168 h post application of the formulation, without show- ing any kidney damage. The rest of the parameters analyzed did not show any variations. This evaluation of he- matological and biochemical effects and of cytokinesis-block micronucleus cytome assay in bovines is proposed as a pre-slaughter control of biomonitoring of the health status of animals, with a focus on food safety for meat consumers.
format Artículo Científico
author Ferré, Daniela Marisol
Jotallan, Paola
Lentini, Valeria
Ludueña, Héctor Ricardo
Romano, Raquel
Gorla, Nora Bibiana María
author_facet Ferré, Daniela Marisol
Jotallan, Paola
Lentini, Valeria
Ludueña, Héctor Ricardo
Romano, Raquel
Gorla, Nora Bibiana María
author_sort Ferré, Daniela Marisol
title Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines
title_short Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines
title_full Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines
title_fullStr Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines
title_full_unstemmed Biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines
title_sort biomonitoring of the hematological, biochemical and genotoxic effects of the mixture cypermethrin plus chlorpyrifos applications in bovines
publisher Science of the Total Environment Editorial
publishDate 2021
url http://repositorio.umaza.edu.ar//handle/00261/2370
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