Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections

Staphylococcus aureus is a microorganism with an incredible capability to adapt to different niches within the human body. Approximately between 20 and 30% of the population is permanently but asymptomatically colonized with S. aureus in the nose, and another 30% may carry S. aureus intermittently....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Genhrke, Ana Katharina, Giai, Constanza, Gómez, Marisa
Formato:	Artículo Científico
Lenguaje:	Inglés
Publicado:	2025
Materias:	Staphylococcus aureus persistence adaptation
Acceso en línea:	https://repositorio.umaza.edu.ar/handle/00261/3564
Aporte de:	UMAZA Digital (Universidad MAZA - Mendoza) de Universidad Juan Agustín MAZA

id	I56-R162-00261-3564
record_format	dspace
spelling	I56-R162-00261-35642025-07-24T02:00:58Z Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections Genhrke, Ana Katharina Giai, Constanza Gómez, Marisa Staphylococcus aureus persistence adaptation Staphylococcus aureus is a microorganism with an incredible capability to adapt to different niches within the human body. Approximately between 20 and 30% of the population is permanently but asymptomatically colonized with S. aureus in the nose, and another 30% may carry S. aureus intermittently. It has been established that nasal colonization is a risk factor for infection in other body sites, including mild to severe skin and soft tissue infections. The skin has distinct features that make it a hostile niche for many bacteria, therefore acting as a strong barrier against invading microorganisms. Healthy skin is desiccated; it has a low pH at the surface; the upper layer is constantly shed to remove attached bacteria; and several host antimicrobial peptides are produced. However, S. aureus is able to overcome these defenses and colonize this microenvironment. Moreover, this bacterium can very efficiently adapt to the stressors present in the skin under pathological conditions, as it occurs in patients with atopic dermatitis or suffering chronic wounds associated with diabetes. The focus of this manuscript is to revise the current knowledge concerning how S. aureus adapts to such diverse skin conditions causing persistent and recurrent infections. 2025-07-23T12:20:57Z 2025-07-23T12:20:57Z 2023 Artículo Científico Gehrke, A.-K. E., Giai, C., & Gómez, M. I. (2023). Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections. Antibiotics, 12(10), 1520. https://doi.org/10.3390/antibiotics12101520 https://repositorio.umaza.edu.ar/handle/00261/3564 eng application/pdf
institution	Universidad Juan Agustín MAZA
institution_str	I-56
repository_str	R-162
collection	UMAZA Digital (Universidad MAZA - Mendoza)
language	Inglés
orig_language_str_mv	eng
topic	Staphylococcus aureus persistence adaptation
spellingShingle	Staphylococcus aureus persistence adaptation Genhrke, Ana Katharina Giai, Constanza Gómez, Marisa Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections
topic_facet	Staphylococcus aureus persistence adaptation
description	Staphylococcus aureus is a microorganism with an incredible capability to adapt to different niches within the human body. Approximately between 20 and 30% of the population is permanently but asymptomatically colonized with S. aureus in the nose, and another 30% may carry S. aureus intermittently. It has been established that nasal colonization is a risk factor for infection in other body sites, including mild to severe skin and soft tissue infections. The skin has distinct features that make it a hostile niche for many bacteria, therefore acting as a strong barrier against invading microorganisms. Healthy skin is desiccated; it has a low pH at the surface; the upper layer is constantly shed to remove attached bacteria; and several host antimicrobial peptides are produced. However, S. aureus is able to overcome these defenses and colonize this microenvironment. Moreover, this bacterium can very efficiently adapt to the stressors present in the skin under pathological conditions, as it occurs in patients with atopic dermatitis or suffering chronic wounds associated with diabetes. The focus of this manuscript is to revise the current knowledge concerning how S. aureus adapts to such diverse skin conditions causing persistent and recurrent infections.
format	Artículo Científico
author	Genhrke, Ana Katharina Giai, Constanza Gómez, Marisa
author_facet	Genhrke, Ana Katharina Giai, Constanza Gómez, Marisa
author_sort	Genhrke, Ana Katharina
title	Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections
title_short	Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections
title_full	Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections
title_fullStr	Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections
title_full_unstemmed	Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections
title_sort	staphylococcus aureus adaptation to the skin in health and persistent/recurrent infections
publishDate	2025
url	https://repositorio.umaza.edu.ar/handle/00261/3564
work_keys_str_mv	AT genhrkeanakatharina staphylococcusaureusadaptationtotheskininhealthandpersistentrecurrentinfections AT giaiconstanza staphylococcusaureusadaptationtotheskininhealthandpersistentrecurrentinfections AT gomezmarisa staphylococcusaureusadaptationtotheskininhealthandpersistentrecurrentinfections
_version_	1842670625810808832

Staphylococcus aureus Adaptation to the Skin in Health and Persistent/Recurrent Infections

Ejemplares similares