Intermolecular perturbation in the self‑assembly of melamine

A theoretical study has been conducted on a set of supramolecular complexes based on 1,3,5-triazine-2,4,6- triamine, or melamine (M), with cyanuric acid (CA), trithiocyanuric acid (TCA), and two mono-substituted derivatives of CA with chlorine (CACl) and bromine (CABr). The study was carried ou...

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Autores principales: Petelski, André N., Duarte, Darío Jorge Roberto, Pamies, Silvana Carina, Peruchena, Nélida María, Sosa, Gladis Laura
Formato: Artículo
Lenguaje:Inglés
Publicado: Springer 2021
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Acceso en línea:http://repositorio.unne.edu.ar/handle/123456789/27918
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Sumario:A theoretical study has been conducted on a set of supramolecular complexes based on 1,3,5-triazine-2,4,6- triamine, or melamine (M), with cyanuric acid (CA), trithiocyanuric acid (TCA), and two mono-substituted derivatives of CA with chlorine (CACl) and bromine (CABr). The study was carried out on 12 complexes, M/(CA)n, M/ (TCA)n, M/(CACl)n, M/(CABr)n, with n = 1, 2 and 3, by the density functional theory employing the ω-B97XD functional with the 6-311++G(d,p) basis set. Information about the intermolecular perturbation over M and the interactions that drive the self-assembly of these species has been obtained from the quantum theory of atoms in molecules and a natural bond orbital analysis. The harmonic oscillator model of aromaticity, the para-delocalization index, the fluctuation aromatic index, and two electron charge density descriptors were used to evaluate the aromaticity of M in each complex. Results show that the hydrogen and halogen (XBs) bond interactions, which direct the self-assembly process in these complexes, are anti-cooperative. Binding energies decrease in the following order: M/ (CA)n > M/(TCA)n > M/(CABr)n > M/(CACl)n (for all values of n). Brominated CA arises as a potential compound to self-assembly with M via XBs.