Application of estradiol benzoate as an alternative to equine chorionic gonadotropin in heat synchronization protocols in sheep
In sheep, traditional estrus synchronization (ES) protocols involve the insertion of a progesterone- or progestogen-containing device, followed by the administration of equine chorionic gonadotropin (eCG) at device removal to induce ovulation. Previous research evaluating estradiol benzoate (EB) as...
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| Autores principales: | , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional del Nordeste
2025
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| Acceso en línea: | https://revistas.unne.edu.ar/index.php/vet/article/view/8740 |
| Aporte de: |
| Sumario: | In sheep, traditional estrus synchronization (ES) protocols involve the insertion of a progesterone- or progestogen-containing device, followed by the administration of equine chorionic gonadotropin (eCG) at device removal to induce ovulation. Previous research evaluating estradiol benzoate (EB) as an alternative to eCG has reported low pregnancy rates. The objectives of this study were to determine (a) the optimal EB dose (100 vs. 200 μg) and timing of administration (0, 24, or 36 h after device removal) within an ES protocol (Experiments I and II), and (b) the pregnancy rate obtained using ES protocols with progesterone plus either eCG or EB, combined with fixed-time artificial insemination (FTAI; Experiment III), in ewes during the breeding season. Experiments I and II indicated that the optimal EB treatment was 100 μg administered at 0 h. In Experiment III, pregnancy rates did not differ between eCG- and EB-based ES protocols. These findings suggest that EB can replace eCG in ES protocols with FTAI at 50–55 h using fresh semen, although further research is needed to refine the timing of FTAI. |
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