Effect of high doses of florfenicol on some hematological parameters in adult goats

The objective of this study was to evaluate the effect of high doses of florfenicol on selectedhematological parameters in adult goats. Six adult Saanen goats were treated intramuscularly with threedoses of florfenicol of 40 mg kg-1, administered at 24-hours intervals. Blood samples with anticoagula...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ruiz, M., Aguirre, F., Marengo, R., Cabaña, E., Kauffmann, I., Gallicet, J., Izquierdo, L., Notta, V., Oprandi, A., Formentini, E.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Nordeste 2025
Materias:
Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/8510
Aporte de:
Descripción
Sumario:The objective of this study was to evaluate the effect of high doses of florfenicol on selectedhematological parameters in adult goats. Six adult Saanen goats were treated intramuscularly with threedoses of florfenicol of 40 mg kg-1, administered at 24-hours intervals. Blood samples with anticoagulantwere collected on day 0 and on days 3, 4, 5, 6, 7, 10 and 12 after treatment initiation. The samples wereanalyzed to determine erythrocytes count, hematocrit, hemoglobin, leukocytes count, neutrophils,lymphocytes, monocytes, and platelets. High doses of florfenicol significantly affect total white blood cellcounts, particularly increasing neutrophils and monocytes. However, these findings contrast with previousstudies reporting negative effects of the same dosage on erythrocyte and leukocyte values in adult goats. Theresults of this study may provide useful information for veterinarians monitoring hematological changes inadult goats undergoing florfenicol treatment.