Equine Asthma Syndrome

Equine Asthma Syndrome (EAS) is a recently adopted term that encompasses chronic, non infectious inflammatory conditions of the lower airways. It facilitates the recognition of shared phenotypic features among these disorders, including airway hyperresponsiveness, bronchospasm, inflammatory cell inf...

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Autores principales: Frezza, Mariel Susana, Picco, Sebastian Julio, Muriel, Marcos Germán
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Nordeste 2025
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Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/8429
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spelling I48-R154-article-84292025-08-02T00:14:37Z Equine Asthma Syndrome Síndrome del Asma Equino Frezza, Mariel Susana Picco, Sebastian Julio Muriel, Marcos Germán Equine Asthma Infammation Airways Equinos Asma Inflamación Vías aéreas Equine Asthma Syndrome (EAS) is a recently adopted term that encompasses chronic, non infectious inflammatory conditions of the lower airways. It facilitates the recognition of shared phenotypic features among these disorders, including airway hyperresponsiveness, bronchospasm, inflammatory cell infiltration, increased mucus production with altered viscoelastic properties, and progressive airway remodeling over time. This terminology provides a broad phenotypic framework that enables subcategorization of the disease based on severity, according to clinical presentation (presence or absence of respiratory effort at rest), triggering factors (barn versus pasture exposure) and supporting diagnostic tests such as endoscopic findings and bronchoalveolar lavage cytology. In this way, two subtypes of asthma are defined, mild to moderate asthma (formerly known as Inflammatory Airway Disease) and severe asthma (formerly known as Recurrent Airway Obstruction). Although the pathogenesis is not yet fully understood, stable housing is recognized as the primary risk factor, as affected horses are potentially exposed to high concentrations of organic and inorganic airborne particles, as well as noxious gases. Treatment focuses on minimizing exposure to airborne dust through environmental management, combined with pharmacological therapy aimed at reducing inflammation and bronchospasm with corticosteroids and bronchodilators  El Síndrome del Asma Equino es un nuevo término propuesto para unificar las afecciones inflamatoriascrónicas no infecciosas de las vías aéreas inferiores. De esta manera, se reconocen las coincidencias fenotípicas entre estas patologías como son la hiperreactividad de las vías aéreas, el broncoespasmo, el infiltrado de células inflamatorias, el aumento en la producción y cambios en la viscoelasticidad del moco y la remodelación de las vías aéreas progresiva a largo plazo. La adopción de este nuevo término proporciona una amplia definición fenotípica que permite la subcategorización de la enfermedad en términos de severidad de la enfermedad, basada en los hallazgos al examen clínico (según la presencia o ausencia de esfuerzo respiratorio en reposo), factores desencadenantes (estabulación / pastura) y en los métodos complementarios de diagnóstico (grado de moco a la endoscopia y citología del lavaje broncoalveolar). De esta manera quedan definidos dos subtipos de asma, el Asma leve-moderado (antes llamado Inflamación de las Pequeñas Vías Aéreas) y el Asma severo (antes llamado Obstrucción Recurrente de las Vías Aéreas). Si bien la etiopatogenia no se encuentra definida con exactitud se reconoce a la estabulación como el principal factor de riesgo ya que estos equinos están potencialmente expuestos a altas concentraciones de partículas aéreas orgánicas e inorgánicas, además de gases nocivos. Su tratamiento se basa en el control ambiental para la reducción en la exposición a partículas de polvo aéreo y la terapia farmacológica para reducción de la inflamación y broncoespasmo por medio de corticoides y broncodilatadores. Universidad Nacional del Nordeste 2025-07-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/8429 10.30972/vet.3628429 Revista Veterinaria; Vol. 36 Núm. 2 (2025); 1-15 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/8429/7958 https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-154
container_title_str Revistas UNNE - Universidad Nacional del Noroeste (UNNE)
language Español
format Artículo revista
topic Equine
Asthma
Infammation
Airways
Equinos
Asma
Inflamación
Vías aéreas
spellingShingle Equine
Asthma
Infammation
Airways
Equinos
Asma
Inflamación
Vías aéreas
Frezza, Mariel Susana
Picco, Sebastian Julio
Muriel, Marcos Germán
Equine Asthma Syndrome
topic_facet Equine
Asthma
Infammation
Airways
Equinos
Asma
Inflamación
Vías aéreas
author Frezza, Mariel Susana
Picco, Sebastian Julio
Muriel, Marcos Germán
author_facet Frezza, Mariel Susana
Picco, Sebastian Julio
Muriel, Marcos Germán
author_sort Frezza, Mariel Susana
title Equine Asthma Syndrome
title_short Equine Asthma Syndrome
title_full Equine Asthma Syndrome
title_fullStr Equine Asthma Syndrome
title_full_unstemmed Equine Asthma Syndrome
title_sort equine asthma syndrome
description Equine Asthma Syndrome (EAS) is a recently adopted term that encompasses chronic, non infectious inflammatory conditions of the lower airways. It facilitates the recognition of shared phenotypic features among these disorders, including airway hyperresponsiveness, bronchospasm, inflammatory cell infiltration, increased mucus production with altered viscoelastic properties, and progressive airway remodeling over time. This terminology provides a broad phenotypic framework that enables subcategorization of the disease based on severity, according to clinical presentation (presence or absence of respiratory effort at rest), triggering factors (barn versus pasture exposure) and supporting diagnostic tests such as endoscopic findings and bronchoalveolar lavage cytology. In this way, two subtypes of asthma are defined, mild to moderate asthma (formerly known as Inflammatory Airway Disease) and severe asthma (formerly known as Recurrent Airway Obstruction). Although the pathogenesis is not yet fully understood, stable housing is recognized as the primary risk factor, as affected horses are potentially exposed to high concentrations of organic and inorganic airborne particles, as well as noxious gases. Treatment focuses on minimizing exposure to airborne dust through environmental management, combined with pharmacological therapy aimed at reducing inflammation and bronchospasm with corticosteroids and bronchodilators 
publisher Universidad Nacional del Nordeste
publishDate 2025
url https://revistas.unne.edu.ar/index.php/vet/article/view/8429
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AT piccosebastianjulio sindromedelasmaequino
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first_indexed 2025-08-17T05:01:58Z
last_indexed 2025-08-17T05:01:58Z
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