Evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in Northeastern Corrientes (Argentina)

Intestinal nematodes in horses represent a significant threat to equine health and the profitability of the horse production system. The periodic administration of anthelmintics is the most used method to control these infections. However, the continuous and indiscriminate use of these drugs without...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Lobayan, Sergio Ivan Jorge
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Nordeste 2025
Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/8126
Aporte de:
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) de Universidad Nacional del Nordeste
id I48-R154-article-8126
record_format ojs
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-154
container_title_str Revistas UNNE - Universidad Nacional del Noroeste (UNNE)
language Español
format Artículo revista
author Lobayan, Sergio Ivan Jorge
spellingShingle Lobayan, Sergio Ivan Jorge
Evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in Northeastern Corrientes (Argentina)
author_facet Lobayan, Sergio Ivan Jorge
author_sort Lobayan, Sergio Ivan Jorge
title Evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in Northeastern Corrientes (Argentina)
title_short Evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in Northeastern Corrientes (Argentina)
title_full Evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in Northeastern Corrientes (Argentina)
title_fullStr Evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in Northeastern Corrientes (Argentina)
title_full_unstemmed Evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in Northeastern Corrientes (Argentina)
title_sort evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in northeastern corrientes (argentina)
description Intestinal nematodes in horses represent a significant threat to equine health and the profitability of the horse production system. The periodic administration of anthelmintics is the most used method to control these infections. However, the continuous and indiscriminate use of these drugs without considering the parasites epidemiological characteristics or performing prior diagnosis contributes to the development of anthelmintic resistance. Resistance of small strongyles to anthelmintics has been well documented for decades in various countries, including Argentina. The aim of this study was to assess the efficacy of the active ingredients fenbendazole and ivermectin against small strongyles in horses from Santo Tomé and Ituzaingó, Corrientes (Argentina), using the fecal egg count reduction test (FECRT) following the new guidelines established by the World Association for the Advancement of Veterinary Parasitology (WAAVP). The study was conducted during 2023 and 2024. Horses from five different owners were included. To evaluate resistance, statistical analysis software (available at http://www.fecrt.com) implementing the FECRT protocol was used. This software compares the average fecal egg counts before and after treatment for each of the compounds studied. Four trials were conducted on 45 horses treated with fenbendazole, and four on 42 horses treated with ivermectin. Resistance to fenbendazole was detected in all four trials, with efficacy rates below 90%. In one of the ivermectin trials, although the fecal egg count reduction was insufficient (less than 90.9%), a second test was recommended before confirming resistance to this compound.
publisher Universidad Nacional del Nordeste
publishDate 2025
url https://revistas.unne.edu.ar/index.php/vet/article/view/8126
work_keys_str_mv AT lobayansergioivanjorge evaluationoftheefficacyoffenbendazoleandivermectinagainstsmallstrongylesinhorsesinnortheasterncorrientesargentina
AT lobayansergioivanjorge evaluaciondelaeficaciadelfenbendazoleivermectinacontrapequenosestrongilosenequinosdelnorestedecorrientesargentina
first_indexed 2025-08-17T05:01:37Z
last_indexed 2025-12-17T05:00:18Z
_version_ 1851730290114822144
spelling I48-R154-article-81262025-12-12T13:35:22Z Evaluation of the efficacy of fenbendazole and ivermectin against small strongyles in horses in Northeastern Corrientes (Argentina) Evaluación de la eficacia del fenbendazol e ivermectina contra pequeños estróngilos en equinos del noreste de Corrientes (Argentina) Lobayan, Sergio Ivan Jorge Intestinal nematodes in horses represent a significant threat to equine health and the profitability of the horse production system. The periodic administration of anthelmintics is the most used method to control these infections. However, the continuous and indiscriminate use of these drugs without considering the parasites epidemiological characteristics or performing prior diagnosis contributes to the development of anthelmintic resistance. Resistance of small strongyles to anthelmintics has been well documented for decades in various countries, including Argentina. The aim of this study was to assess the efficacy of the active ingredients fenbendazole and ivermectin against small strongyles in horses from Santo Tomé and Ituzaingó, Corrientes (Argentina), using the fecal egg count reduction test (FECRT) following the new guidelines established by the World Association for the Advancement of Veterinary Parasitology (WAAVP). The study was conducted during 2023 and 2024. Horses from five different owners were included. To evaluate resistance, statistical analysis software (available at http://www.fecrt.com) implementing the FECRT protocol was used. This software compares the average fecal egg counts before and after treatment for each of the compounds studied. Four trials were conducted on 45 horses treated with fenbendazole, and four on 42 horses treated with ivermectin. Resistance to fenbendazole was detected in all four trials, with efficacy rates below 90%. In one of the ivermectin trials, although the fecal egg count reduction was insufficient (less than 90.9%), a second test was recommended before confirming resistance to this compound. Los nematodos gastrointestinales de los equinos representan una seria amenaza para la salud y la rentabilidad de la producción equina. La administración periódica de antihelmínticos es el método más empleado para el control de las infecciones por estos nematodos. El uso continuo e indiscriminado, sin considerar aspectos epidemiológicos de los parásitos y sin realización de diagnóstico previo, favorece a la aparición del fenómeno de resistencia antihelmíntica. La resistencia antihelmíntica de los pequeños estróngilos de los equinos es un problema bien descripto e informado desde hace décadas en distintos países del mundo y también en la Argentina. El objetivo de este trabajo fue determinar la prevalencia de la resistencia antihelmíntica a los principios activos Fenbendazole e Ivermectina en pequeños estrongilos de equinos en los Departamentos Santo Tomé e Ituzaingó, Corrientes (Argentina) mediante el test de reducción de conteo de huevos siguiendo los nuevos lineamientos de la Asociación Mundial para el Avance de la Parasitología. El estudio se llevó a cabo durante los años 2024 y 2025. Se seleccionaron equinos pertenecientes a cinco propietarios. Para el diagnóstico de resistencia, se utilizó el software de análisis estadístico disponible en http://www.fecrt.com, que implementa la prueba del test de reducción del conteo de huevos en materia fecal utilizando los recuentos pre y postratamiento con cada uno de los principios activos estudiados. Se llevaron a cabo ocho ensayos, en cuatro de ellos se detectó resistencia al  fenbendazole con una eficacia inferior al 90%. En una de las pruebas de eficacia de la ivermectina, si bien se detectó una reducción insuficiente en el conteo de huevos, se recomendó efectuar una segunda prueba antes de declarar la presencia de resistencia a este principio activo. Universidad Nacional del Nordeste 2025-12-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/8126 10.30972/vet.3628126 Revista Veterinaria; Vol. 36 No. 2 (2025); 1-5 Revista Veterinaria; Vol. 36 Núm. 2 (2025); 1-5 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/8126/8569 Derechos de autor 2025 Sergio Ivan Jorge Lobayan https://creativecommons.org/licenses/by-nc/4.0

Ejemplares similares