Metastasis in the parotid gland from a renal clear cell carcinoma: a clinical- pathological study
Primary and secondary malignant tumors have the potential to develop in the parotid gland, as documented in the literature. However, the majority of metastatic cases originate from head and neck neoplasms, with squamous cell carcinoma of the skin being the most common. On the other hand, clear cell...
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| Autores principales: | , , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Facultad de Odontología de la Universidad Nacional del Nordeste (FOUNNE)
2024
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| Acceso en línea: | https://revistas.unne.edu.ar/index.php/rfo/article/view/8050 |
| Aporte de: |
| Sumario: | Primary and secondary malignant tumors have the potential to develop in the parotid gland, as documented in the literature. However, the majority of metastatic cases originate from head and neck neoplasms, with squamous cell carcinoma of the skin being the most common. On the other hand, clear cell renal carcinoma represents 70-80% of kidney cancers, producing regional and distant metastases through the renal vein. Metastases from this type of renal cancer to the head and neck region have been diagnosed in 14-16% of patients, though metastases to the parotid gland are extremely rare. This study presents the case of a female patient who developed a late parotid metastatic tumor following left unilateral nephrectomy for clear cell carcinoma, with itsrenal origin confirmed through positive CD10 marker expression. Renal cell carcinoma exhibits a high metastatic potential. At the time of diagnosis, 25-30% of patients present distant disease (synchronous metastases), especially involving the lungs, bones, liver, adrenal glands, contralateral kidney, and brain. However, renal cell carcinoma is also characterized by the ability to produce late metastases (metachronous metastases), which can appear even decades after initial diagnosis. In this case, the patient’s renal carcinoma, initially diagnosed in 2014, resulted in a parotid metastasis in 2023, nearly a decade later. |
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