Adjuvant treatment of canine distemper with natural apitoxin
Canine distemper (CD) is the most widespread and highly contagious viral disease in dogs worldwide, with a high mortality rate. No specific treatment exists, only supportive care with antibiotics aimed at preventing secondary bacterial infections. Vaccination is recommended for the control of CD. Co...
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| Autores principales: | , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional del Nordeste
2025
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| Materias: | |
| Acceso en línea: | https://revistas.unne.edu.ar/index.php/vet/article/view/7985 |
| Aporte de: |
| Sumario: | Canine distemper (CD) is the most widespread and highly contagious viral disease in dogs worldwide, with a high mortality rate. No specific treatment exists, only supportive care with antibiotics aimed at preventing secondary bacterial infections. Vaccination is recommended for the control of CD. Consequently, this study was conducted to evaluate the immunomodulatory effect of natural apitoxin through bee stings (Apis mellifera) as an adjuvant in the treatment of this disease. Following anamnesis, clinical examination, and physical assessment of suspected cases, a CD test and serological confirmation were performed. Apitoxin application was administered every 24 and 48 hours over three days, using a completely randomized experimental design with a 95% confidence level. Immunoglobulin G (IgG) and Immunoglobulin M (IgM) titers were determined by immunoturbidimetry. Variables such as age, sex, weight (small < 8 kg, large > 8 kg), distemper vaccination, and disease stage showed no influence on immunoglobulin levels. However, ANOVA analysis revealed a significant increase in IgG levels 21 days post-apitoxin application every 48 hours, suggesting this alternative as a potential adjuvant therapy to enhance the immune response in CD supportive treatment. |
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