Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter

The objective of this work was to study the elimination of oxytetracycline (OTC) and fosfomycin (FOS) in sow colostrum/milk and its impact on some microbiological aspects and on intestinal morpho-physiological and zootechnical parameters of the litter. Colostrum/milk samples from sows treated during...

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Autores principales: Fernández, M. B., Decundo, J. M., Martínez, G. O., Diéguez, S. N., Soraci, A. L.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Nordeste 2021
Materias:
cerda
lechones
calostro
leche
antibióticos
resistencia bacteriana
sow
piglets
colostrum
milk
antibiotics
bacterial resistance
Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/4735
Aporte de:
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) de Universidad Nacional del Nordeste
id I48-R154-article-4735
record_format ojs
spelling I48-R154-article-47352025-02-12T21:59:23Z Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter Eliminación de residuos de oxitetraciclina y fosfomicina en calostro y leche de cerda: efecto sobre la camada Fernández, M. B. Decundo, J. M. Martínez, G. O. Diéguez, S. N. Soraci, A. L. cerda lechones calostro leche antibióticos resistencia bacteriana sow piglets colostrum milk antibiotics bacterial resistance The objective of this work was to study the elimination of oxytetracycline (OTC) and fosfomycin (FOS) in sow colostrum/milk and its impact on some microbiological aspects and on intestinal morpho-physiological and zootechnical parameters of the litter. Colostrum/milk samples from sows treated during the period of delivery with OTC solution and disodium FOS by the intramuscular route were analyzed. Colostrum intake with residual concentrations of antibiotics and intestinal and zootechnical parameters of suckling piglets, were evaluated. The mean residual concentrations of OTC and FOS in colostrum/milk were 0.48 and 1.55 µg/ml and the average antibiotic intake/piglet was 0.13 and 0.50 mg/kg body weight, respectively. While ingestion of colostrum with FOS residues showed less impact than OTC on the microbiological, morpho-physiological and intestinal enzymatic biochemistry of suckling piglets, any of the antibiotics affected the zootechnical parameters of the litters. Nevertheless, the low concentrations of antibiotics ingested with colostrum would be a potential risk of developing bacterial resistance, thus their prophylactic administration during the peri-partum should be reconsidered. El objetivo del presente trabajo fue estudiar la eliminación de oxitetraciclina (OTC) y fosfomicina (FOS) en calostro y leche de cerda, su impacto sobre algunos aspectos microbiológicos y morfo-fisiológicos intestinales, así como parámetros zootécnicos de la camada. Se analizaron muestras de calostro y leche de cerdas tratadas durante el peri-parto con OTC solución y FOS disódica vía intramuscular. Se evaluó la ingesta de calostro con concentraciones residuales de antibióticos, así como parámetros intestinales y zootécnicos de lechones lactantes. Las concentraciones medias residuales de OTC y FOS en calostro/leche fueron 0,48 y 1,55 µg/ml y la ingestión media de antibiótico/lechón fue de 0,13 y 0,50 mg/kg peso vivo, respectivamente. Si bien la ingestión de calostro con residuos de FOS mostró menor impacto que OTC sobre los aspectos microbiológicos y morfo-fisiológicos, así como sobre la bioquímica enzimática intestinal de lechones lactantes, ambos antibióticos no afectaron los resultados de los parámetros zootécnicos de las camadas. No obstante, las bajas concentraciones de antibióticos ingeridos con el calostro serían un potencial riesgo de desarrollo de resistencia bacteriana, por lo cual la aplicación profiláctica de los mismos durante el peri-parto debería ser reconsiderada. Universidad Nacional del Nordeste 2021-04-07 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/4735 10.30972/vet.3124735 Revista Veterinaria; Vol. 31 Núm. 2 (2020); 146-151 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/4735/4434 Derechos de autor 2021 M. B. Fernández, J. M. Decundo, G. O. Martínez, S. N. Diéguez, A. L. Soraci https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-154
container_title_str Revistas UNNE - Universidad Nacional del Noroeste (UNNE)
language Español
format Artículo revista
topic cerda
lechones
calostro
leche
antibióticos
resistencia bacteriana
sow
piglets
colostrum
milk
antibiotics
bacterial resistance
spellingShingle cerda
lechones
calostro
leche
antibióticos
resistencia bacteriana
sow
piglets
colostrum
milk
antibiotics
bacterial resistance
Fernández, M. B.
Decundo, J. M.
Martínez, G. O.
Diéguez, S. N.
Soraci, A. L.
Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter
topic_facet cerda
lechones
calostro
leche
antibióticos
resistencia bacteriana
sow
piglets
colostrum
milk
antibiotics
bacterial resistance
author Fernández, M. B.
Decundo, J. M.
Martínez, G. O.
Diéguez, S. N.
Soraci, A. L.
author_facet Fernández, M. B.
Decundo, J. M.
Martínez, G. O.
Diéguez, S. N.
Soraci, A. L.
author_sort Fernández, M. B.
title Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter
title_short Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter
title_full Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter
title_fullStr Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter
title_full_unstemmed Elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter
title_sort elimination of residual concentrations of oxytetracycline and fosfomycin in colostrum and sow milk: effect on the litter
description The objective of this work was to study the elimination of oxytetracycline (OTC) and fosfomycin (FOS) in sow colostrum/milk and its impact on some microbiological aspects and on intestinal morpho-physiological and zootechnical parameters of the litter. Colostrum/milk samples from sows treated during the period of delivery with OTC solution and disodium FOS by the intramuscular route were analyzed. Colostrum intake with residual concentrations of antibiotics and intestinal and zootechnical parameters of suckling piglets, were evaluated. The mean residual concentrations of OTC and FOS in colostrum/milk were 0.48 and 1.55 µg/ml and the average antibiotic intake/piglet was 0.13 and 0.50 mg/kg body weight, respectively. While ingestion of colostrum with FOS residues showed less impact than OTC on the microbiological, morpho-physiological and intestinal enzymatic biochemistry of suckling piglets, any of the antibiotics affected the zootechnical parameters of the litters. Nevertheless, the low concentrations of antibiotics ingested with colostrum would be a potential risk of developing bacterial resistance, thus their prophylactic administration during the peri-partum should be reconsidered.
publisher Universidad Nacional del Nordeste
publishDate 2021
url https://revistas.unne.edu.ar/index.php/vet/article/view/4735
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first_indexed 2025-05-17T05:10:12Z
last_indexed 2025-05-17T05:10:12Z
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