Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients

Factor V Leiden and mutation of prothrombin gene G20210A have been associated with poor results in the early post-kidney transplantation period. Its long-term importance in stable patients has yet to be evaluated. We studied the prevalence of these inherited mutations and their relationship to throm...

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Detalles Bibliográficos
Autores principales:	Chiurchiu, Carlos, de Alvarellos, T., Sánchez, A., Cortiñas, D., Douthat, Walter Guillermo, De La Fuente, Jorge, De Arteaga, Javier, Massari, Pablo U.
Formato:	Artículo PeerReviewed
Lenguaje:	Español
Publicado:	2010
Materias:	R Medicina (General)
Acceso en línea:	http://pa.bibdigital.ucc.edu.ar/5010/1/A_Chiurchiu.pdf
Aporte de:	Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba

id	I38-R144-5010
record_format	dspace
spelling	I38-R144-50102025-11-10T14:53:22Z http://pa.bibdigital.ucc.edu.ar/5010/ Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients Chiurchiu, Carlos de Alvarellos, T. Sánchez, A. Cortiñas, D. Douthat, Walter Guillermo De La Fuente, Jorge De Arteaga, Javier Massari, Pablo U. R Medicina (General) Factor V Leiden and mutation of prothrombin gene G20210A have been associated with poor results in the early post-kidney transplantation period. Its long-term importance in stable patients has yet to be evaluated. We studied the prevalence of these inherited mutations and their relationship to thrombotic events in 82 Argentine renal transplant recipients with adequate long-term kidney function. In aggregate, 7.2% of patients were carriers of these mutations; however, their presence did not show any association with thrombotic events or renal function alterations. The routine evaluation for these mutations does not seem to be cost-effective in renal transplant patients. 2010-12-31 Artículo PeerReviewed application/pdf spa http://pa.bibdigital.ucc.edu.ar/5010/1/A_Chiurchiu.pdf Chiurchiu, Carlos, de Alvarellos, T., Sánchez, A., Cortiñas, D., Douthat, Walter Guillermo ORCID: https://orcid.org/0000-0002-4644-6003 <https://orcid.org/0000-0002-4644-6003>, De La Fuente, Jorge, De Arteaga, Javier and Massari, Pablo U. (2010) Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients. Transplantation Proceedings, 42 (1). pp. 282-283. ISSN 00411345 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.transproceed.2009.11.033
institution	Universidad Católica de Córdoba
institution_str	I-38
repository_str	R-144
collection	Producción Académica Universidad Católica de Córdoba (UCCor)
language	Español
orig_language_str_mv	spa
topic	R Medicina (General)
spellingShingle	R Medicina (General) Chiurchiu, Carlos de Alvarellos, T. Sánchez, A. Cortiñas, D. Douthat, Walter Guillermo De La Fuente, Jorge De Arteaga, Javier Massari, Pablo U. Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients
topic_facet	R Medicina (General)
description	Factor V Leiden and mutation of prothrombin gene G20210A have been associated with poor results in the early post-kidney transplantation period. Its long-term importance in stable patients has yet to be evaluated. We studied the prevalence of these inherited mutations and their relationship to thrombotic events in 82 Argentine renal transplant recipients with adequate long-term kidney function. In aggregate, 7.2% of patients were carriers of these mutations; however, their presence did not show any association with thrombotic events or renal function alterations. The routine evaluation for these mutations does not seem to be cost-effective in renal transplant patients.
format	Artículo PeerReviewed
author	Chiurchiu, Carlos de Alvarellos, T. Sánchez, A. Cortiñas, D. Douthat, Walter Guillermo De La Fuente, Jorge De Arteaga, Javier Massari, Pablo U.
author_facet	Chiurchiu, Carlos de Alvarellos, T. Sánchez, A. Cortiñas, D. Douthat, Walter Guillermo De La Fuente, Jorge De Arteaga, Javier Massari, Pablo U.
author_sort	Chiurchiu, Carlos
title	Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients
title_short	Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients
title_full	Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients
title_fullStr	Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients
title_full_unstemmed	Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients
title_sort	thrombophilic mutations: no association with thrombotic events in renal transplant recipients
publishDate	2010
url	http://pa.bibdigital.ucc.edu.ar/5010/1/A_Chiurchiu.pdf
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Thrombophilic Mutations: no association with thrombotic events in renal transplant recipients

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