Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham

Bioassay-guided fractionation of an ethanolic extract of the aerial parts of Dolichandra cynanchoides Cham. (Bignoniaceae) led to the isolation of a natural wax with anti-insect activity against Spodoptera frugiperda (Noctuidae) and Epilachna paenulata (Coleptera). The compound was identified spect...

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Detalles Bibliográficos
Autores principales:	Díaz Napal, Georgina, Carpinella, María Cecilia, Palacios, Sara María
Formato:	Artículo acceptedVersion
Lenguaje:	Español
Publicado:	MDPI AG 2016
Materias:	Q Ciencia (General) QD Química
Acceso en línea:	http://pa.bibdigital.ucc.edu.ar/4228/1/A_D%C3%ADazNapal_Carpinella_Palacios.pdf
Aporte de:	Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba

id	I38-R144-4228
record_format	dspace
spelling	I38-R144-42282024-03-19T14:00:14Z http://pa.bibdigital.ucc.edu.ar/4228/ Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham Díaz Napal, Georgina Carpinella, María Cecilia Palacios, Sara María Q Ciencia (General) QD Química Bioassay-guided fractionation of an ethanolic extract of the aerial parts of Dolichandra cynanchoides Cham. (Bignoniaceae) led to the isolation of a natural wax with anti-insect activity against Spodoptera frugiperda (Noctuidae) and Epilachna paenulata (Coleptera). The compound was identified spectroscopically as an ester of a C27 fatty acid and a C25 alcohol, pentacosyl heptacosanoate (1). The effective doses of 1 for 50% feeding inhibition (ED50) of S. frugiperda and E. paenulata were 0.82 and 8.53 µg/cm2, respectively, in a choice test, while azadirachtin showed ED50 of 0.10 and 0.59 µg/cm2, respectively. In a no-choice test, both insects refused to feed on leaves treated with 1 at doses of 0.1 µg/cm2 or greater inhibiting larval growth and dramatically reducing survival. The lethal doses 50 (LD50) of 1 were 0.39 and 0.68 µg/cm2 for S. frugiperda and E. paenulata, respectively. These results indicate that 1 has potential for development as botanical insecticides. Similar esters might be obtainable in large quantities as many edible crops produce wax esters that are discarded during food processing. Research on these materials could lead to the detection of similar waxes with insecticidal activity. MDPI AG 2016-12-31 application/pdf spa http://pa.bibdigital.ucc.edu.ar/4228/1/A_D%C3%ADazNapal_Carpinella_Palacios.pdf Díaz Napal, Georgina ORCID: https://orcid.org/0000-0003-2440-2488 <https://orcid.org/0000-0003-2440-2488>, Carpinella, María Cecilia ORCID: https://orcid.org/0000-0001-5553-1851 <https://orcid.org/0000-0001-5553-1851> and Palacios, Sara María (2016) Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham. Molecules, 21 (8). ISSN 1420-3049 info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.3390/molecules21081039 info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/acceptedVersion Fil: Díaz Napal, Georgina. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Carpinella, María Cecilia. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Palacios, Sara María. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/deed.es
institution	Universidad Católica de Córdoba
institution_str	I-38
repository_str	R-144
collection	Producción Académica Universidad Católica de Córdoba (UCCor)
language	Español
orig_language_str_mv	spa
topic	Q Ciencia (General) QD Química
spellingShingle	Q Ciencia (General) QD Química Díaz Napal, Georgina Carpinella, María Cecilia Palacios, Sara María Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham
topic_facet	Q Ciencia (General) QD Química
description	Bioassay-guided fractionation of an ethanolic extract of the aerial parts of Dolichandra cynanchoides Cham. (Bignoniaceae) led to the isolation of a natural wax with anti-insect activity against Spodoptera frugiperda (Noctuidae) and Epilachna paenulata (Coleptera). The compound was identified spectroscopically as an ester of a C27 fatty acid and a C25 alcohol, pentacosyl heptacosanoate (1). The effective doses of 1 for 50% feeding inhibition (ED50) of S. frugiperda and E. paenulata were 0.82 and 8.53 µg/cm2, respectively, in a choice test, while azadirachtin showed ED50 of 0.10 and 0.59 µg/cm2, respectively. In a no-choice test, both insects refused to feed on leaves treated with 1 at doses of 0.1 µg/cm2 or greater inhibiting larval growth and dramatically reducing survival. The lethal doses 50 (LD50) of 1 were 0.39 and 0.68 µg/cm2 for S. frugiperda and E. paenulata, respectively. These results indicate that 1 has potential for development as botanical insecticides. Similar esters might be obtainable in large quantities as many edible crops produce wax esters that are discarded during food processing. Research on these materials could lead to the detection of similar waxes with insecticidal activity.
format	Artículo Artículo acceptedVersion
author	Díaz Napal, Georgina Carpinella, María Cecilia Palacios, Sara María
author_facet	Díaz Napal, Georgina Carpinella, María Cecilia Palacios, Sara María
author_sort	Díaz Napal, Georgina
title	Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham
title_short	Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham
title_full	Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham
title_fullStr	Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham
title_full_unstemmed	Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham
title_sort	insecticidal properties of a highly potent wax isolated from dolichandra cynanchoides cham
publisher	MDPI AG
publishDate	2016
url	http://pa.bibdigital.ucc.edu.ar/4228/1/A_D%C3%ADazNapal_Carpinella_Palacios.pdf
work_keys_str_mv	AT diaznapalgeorgina insecticidalpropertiesofahighlypotentwaxisolatedfromdolichandracynanchoidescham AT carpinellamariacecilia insecticidalpropertiesofahighlypotentwaxisolatedfromdolichandracynanchoidescham AT palaciossaramaria insecticidalpropertiesofahighlypotentwaxisolatedfromdolichandracynanchoidescham
_version_	1832592491248877568

Insecticidal Properties of a Highly Potent Wax Isolated from Dolichandra cynanchoides Cham

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