Solid-state characterization of two polymorphic forms of R-albuterol sulfate

R-Albuterol (levalbuterol) is a drug used for asthma therapy and some formulations of it are in solid dosage forms. The aim of this work was to describe and characterize two polymorphic modifications of R-albuterol sulfate by means of typical structure-sensitive analytical techniques such as X-ray p...

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Autores principales: Palacios, M.A., Cuffini, S., Badini, R., Karlsson, A., Palacios, S.M.
Formato: Artículo
Lenguaje:Español
Publicado: Elseiver 2007
Materias:
R Medicina (General)
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/4033/1/A_Palacios_Cuffini_Badini_Karlsson_Palacios.pdf
Aporte de:
Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-4033
record_format dspace
spelling I38-R144-40332025-04-11T20:21:52Z http://pa.bibdigital.ucc.edu.ar/4033/ Solid-state characterization of two polymorphic forms of R-albuterol sulfate Palacios, M.A. Cuffini, S. Badini, R. Karlsson, A. Palacios, S.M. R Medicina (General) R-Albuterol (levalbuterol) is a drug used for asthma therapy and some formulations of it are in solid dosage forms. The aim of this work was to describe and characterize two polymorphic modifications of R-albuterol sulfate by means of typical structure-sensitive analytical techniques such as X-ray powder diffraction, FT-IR spectroscopy, visual and microscopic inspection, and DSC. Substantial differences were observed between the solid-state properties of the crystals, confirming the existence of at least two polymorphic forms for R-albuterol sulfate: Form I and Form II. Elseiver 2007-03-12 info:eu-repo/semantics/article info:eu-repo/semantics/closedAccess application/pdf spa http://pa.bibdigital.ucc.edu.ar/4033/1/A_Palacios_Cuffini_Badini_Karlsson_Palacios.pdf Palacios, M.A., Cuffini, S., Badini, R., Karlsson, A. and Palacios, S.M. (2007) Solid-state characterization of two polymorphic forms of R-albuterol sulfate. Journal of Pharmaceutical and Biomedical Analysis, 43 (4). pp. 1531-1534. ISSN 0731-7085 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jpba.2006.11.009
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic R Medicina (General)
spellingShingle R Medicina (General)
Palacios, M.A.
Cuffini, S.
Badini, R.
Karlsson, A.
Palacios, S.M.
Solid-state characterization of two polymorphic forms of R-albuterol sulfate
topic_facet R Medicina (General)
description R-Albuterol (levalbuterol) is a drug used for asthma therapy and some formulations of it are in solid dosage forms. The aim of this work was to describe and characterize two polymorphic modifications of R-albuterol sulfate by means of typical structure-sensitive analytical techniques such as X-ray powder diffraction, FT-IR spectroscopy, visual and microscopic inspection, and DSC. Substantial differences were observed between the solid-state properties of the crystals, confirming the existence of at least two polymorphic forms for R-albuterol sulfate: Form I and Form II.
format Artículo
author Palacios, M.A.
Cuffini, S.
Badini, R.
Karlsson, A.
Palacios, S.M.
author_facet Palacios, M.A.
Cuffini, S.
Badini, R.
Karlsson, A.
Palacios, S.M.
author_sort Palacios, M.A.
title Solid-state characterization of two polymorphic forms of R-albuterol sulfate
title_short Solid-state characterization of two polymorphic forms of R-albuterol sulfate
title_full Solid-state characterization of two polymorphic forms of R-albuterol sulfate
title_fullStr Solid-state characterization of two polymorphic forms of R-albuterol sulfate
title_full_unstemmed Solid-state characterization of two polymorphic forms of R-albuterol sulfate
title_sort solid-state characterization of two polymorphic forms of r-albuterol sulfate
publisher Elseiver
publishDate 2007
url http://pa.bibdigital.ucc.edu.ar/4033/1/A_Palacios_Cuffini_Badini_Karlsson_Palacios.pdf
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AT cuffinis solidstatecharacterizationoftwopolymorphicformsofralbuterolsulfate
AT badinir solidstatecharacterizationoftwopolymorphicformsofralbuterolsulfate
AT karlssona solidstatecharacterizationoftwopolymorphicformsofralbuterolsulfate
AT palaciossm solidstatecharacterizationoftwopolymorphicformsofralbuterolsulfate
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