High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina
In the study presented here, the genetic characteristics of methicillin-susceptible Staphylococcus aureus (MSSA) strains isolated from patients attending hospitals in the city of Córdoba, Argentina, during 1999-2002 were evaluated to determine their genetic relationship with methicillin-resistant S....
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| Formato: | Artículo |
| Lenguaje: | Español |
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Springer Nature
2007
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| Acceso en línea: | http://pa.bibdigital.ucc.edu.ar/4030/1/A_Sola....pdf |
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I38-R144-40302025-04-14T19:12:41Z http://pa.bibdigital.ucc.edu.ar/4030/ High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina Sola, C. Saka, H.A. Vindel, A. Bocco, José Luis Monterisi, A. Rocchi, M. Díaz, E. Lomberghini, R. Littvik, A.M. López, T. Yudowsky, S. Carvajal, L. Culasso, C. Perlo Morales, O. Aissa, M.S. Vilaro, M. Bongiovanni, M.E. Mangiaterra, S. Barbon, S. Wolff, L. Vercelli, B. D'Andrea, E.M. López, A. Pino, Gustavo Ariel Muñoz, V. Bottiglieri, Marina Teresita R Medicina (General) In the study presented here, the genetic characteristics of methicillin-susceptible Staphylococcus aureus (MSSA) strains isolated from patients attending hospitals in the city of Córdoba, Argentina, during 1999-2002 were evaluated to determine their genetic relationship with methicillin-resistant S. aureus (MRSA) clones as part of an effort to control the potential emergence of new epidemic MRSA strains. The results showed there is a high frequency of MSSA strains carrying Panton-Valentine leukocidin genes in invasive infections in Córdoba, Argentina, particularly in those occurring in hospital settings. Panton-Valentine leukocidin genes were found in the genomic background of one clone (ST30-N pulsotype) belonging to a successful internationally distributed MSSA lineage (clonal complex 30), which is closely related to the EMRSA-16 pandemic clone. These genes were also detected in the ancestral clone (ST5-M pulsotype) of the most prevalent MRSA epidemic clone causing healthcare-associated infections in this region, known as the Cordobes/Chilean clone. The molecular characterization of circulating MSSA strains, including the detection of Panton-Valentine leukocidin genes, is thus a useful marker for investigating the evolving epidemiology of hospital- and community-acquired MRSA clones. Springer Nature 2007-04-30 info:eu-repo/semantics/article info:eu-repo/semantics/closedAccess application/pdf spa http://pa.bibdigital.ucc.edu.ar/4030/1/A_Sola....pdf Sola, C., Saka, H.A., Vindel, A., Bocco, José Luis, Monterisi, A., Rocchi, M., Díaz, E., Lomberghini, R., Littvik, A.M., López, T., Yudowsky, S., Carvajal, L., Culasso, C., Perlo Morales, O., Aissa, M.S., Vilaro, M., Bongiovanni, M.E., Mangiaterra, S., Barbon, S., Wolff, L., Vercelli, B., D'Andrea, E.M., López, A., Pino, Gustavo Ariel, Muñoz, V. and Bottiglieri, Marina Teresita ORCID: https://orcid.org/0000-0001-6215-9488 <https://orcid.org/0000-0001-6215-9488> (2007) High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina. European Journal of Clinical Microbiology and Infectious Diseases, 26 (4). pp. 281-286. ISSN 0934-9723 info:eu-repo/semantics/altIdentifier/doi/10.1007/s10096-007-0278-4 |
| institution |
Universidad Católica de Córdoba |
| institution_str |
I-38 |
| repository_str |
R-144 |
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Producción Académica Universidad Católica de Córdoba (UCCor) |
| language |
Español |
| orig_language_str_mv |
spa |
| topic |
R Medicina (General) |
| spellingShingle |
R Medicina (General) Sola, C. Saka, H.A. Vindel, A. Bocco, José Luis Monterisi, A. Rocchi, M. Díaz, E. Lomberghini, R. Littvik, A.M. López, T. Yudowsky, S. Carvajal, L. Culasso, C. Perlo Morales, O. Aissa, M.S. Vilaro, M. Bongiovanni, M.E. Mangiaterra, S. Barbon, S. Wolff, L. Vercelli, B. D'Andrea, E.M. López, A. Pino, Gustavo Ariel Muñoz, V. Bottiglieri, Marina Teresita High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina |
| topic_facet |
R Medicina (General) |
| description |
In the study presented here, the genetic characteristics of methicillin-susceptible Staphylococcus aureus (MSSA) strains isolated from patients attending hospitals in the city of Córdoba, Argentina, during 1999-2002 were evaluated to determine their genetic relationship with methicillin-resistant S. aureus (MRSA) clones as part of an effort to control the potential emergence of new epidemic MRSA strains. The results showed there is a high frequency of MSSA strains carrying Panton-Valentine leukocidin genes in invasive infections in Córdoba, Argentina, particularly in those occurring in hospital settings. Panton-Valentine leukocidin genes were found in the genomic background of one clone (ST30-N pulsotype) belonging to a successful internationally distributed MSSA lineage (clonal complex 30), which is closely related to the EMRSA-16 pandemic clone. These genes were also detected in the ancestral clone (ST5-M pulsotype) of the most prevalent MRSA epidemic clone causing healthcare-associated infections in this region, known as the Cordobes/Chilean clone. The molecular characterization of circulating MSSA strains, including the detection of Panton-Valentine leukocidin genes, is thus a useful marker for investigating the evolving epidemiology of hospital- and community-acquired MRSA clones. |
| format |
Artículo |
| author |
Sola, C. Saka, H.A. Vindel, A. Bocco, José Luis Monterisi, A. Rocchi, M. Díaz, E. Lomberghini, R. Littvik, A.M. López, T. Yudowsky, S. Carvajal, L. Culasso, C. Perlo Morales, O. Aissa, M.S. Vilaro, M. Bongiovanni, M.E. Mangiaterra, S. Barbon, S. Wolff, L. Vercelli, B. D'Andrea, E.M. López, A. Pino, Gustavo Ariel Muñoz, V. Bottiglieri, Marina Teresita |
| author_facet |
Sola, C. Saka, H.A. Vindel, A. Bocco, José Luis Monterisi, A. Rocchi, M. Díaz, E. Lomberghini, R. Littvik, A.M. López, T. Yudowsky, S. Carvajal, L. Culasso, C. Perlo Morales, O. Aissa, M.S. Vilaro, M. Bongiovanni, M.E. Mangiaterra, S. Barbon, S. Wolff, L. Vercelli, B. D'Andrea, E.M. López, A. Pino, Gustavo Ariel Muñoz, V. Bottiglieri, Marina Teresita |
| author_sort |
Sola, C. |
| title |
High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina |
| title_short |
High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina |
| title_full |
High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina |
| title_fullStr |
High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina |
| title_full_unstemmed |
High frequency of Panton-Valentine leukocidin genes in invasive methicillin-susceptible Staphylococcus aureus strains and the relationship with methicillin-resistant Staphylococcus aureus in Córdoba, Argentina |
| title_sort |
high frequency of panton-valentine leukocidin genes in invasive methicillin-susceptible staphylococcus aureus strains and the relationship with methicillin-resistant staphylococcus aureus in córdoba, argentina |
| publisher |
Springer Nature |
| publishDate |
2007 |
| url |
http://pa.bibdigital.ucc.edu.ar/4030/1/A_Sola....pdf |
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