Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy

PURPOSE: To present external eye findings and the observation of iris atrophy in patients with climatic droplet keratopathy (CDK). METHODS: Twenty-three patients with CDK and 13 controls living in a semideserted plain of the Argentine Patagonia were studied. Besides a comprehensive eye examination,...

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Autores principales: Urrets Zavalía, Julio, Maccio, J.Pablo, Knoll, Erna, Cafaro, Thamara, Urrets Zavalía, Enrique Alberto, Serra, Horacio M.
Formato: Artículo
Lenguaje:Español
Publicado: 2007
Materias:
RE Oftalmología
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/4021/1/A_UrretsZaval%C3%ADa_Knoll_Maccio_UrretsZaval%C3%ADa_Saad_Serra.pdf
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Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-4021
record_format dspace
spelling I38-R144-40212025-04-14T19:48:06Z http://pa.bibdigital.ucc.edu.ar/4021/ Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy Urrets Zavalía, Julio Maccio, J.Pablo Knoll, Erna Cafaro, Thamara Urrets Zavalía, Enrique Alberto Serra, Horacio M. RE Oftalmología PURPOSE: To present external eye findings and the observation of iris atrophy in patients with climatic droplet keratopathy (CDK). METHODS: Twenty-three patients with CDK and 13 controls living in a semideserted plain of the Argentine Patagonia were studied. Besides a comprehensive eye examination, Cochet-Bonnet aesthesiometry, Schirmer II test, breakup time (BUT), and surface staining were performed. According to corneal findings, eyes were grouped as grade 1 (confluent translucent microdroplets localized in the limbic region of the horizontal quadrants); grade 2 (band-shaped subepithelial haziness compromising the central cornea); and grade 3 (previously described lesions with yellow subepithelial droplets). Results were analyzed with the Fisher, Mann-Whitney, and Spearman tests, which were considered significant at P < 0.05. RESULTS: Nineteen of 23 patients with CDK had bilateral disease, which was asymmetric in 2 of them. Sixteen eyes had grade 1, 21 eyes had grade 2, and 5 eyes had grade 3 disease. Aesthesiometry showed that the more advanced the disease, the more profound the corneal hypoesthesia (P = 0.0008). BUT and ocular surface staining significantly differed between eyes with grade 3 and grade 1, grade 3 and grade 2, and grade 3 and controls. In 38.09% of eyes with CDK and in none of the controls, sectorial depigmentation and atrophy of the inferior iris were observed. CONCLUSIONS: A severe decrease of corneal sensitivity was observed in advanced stages of CDK. Some degree of dry eye was present in most patients, but severe disease was infrequent at any stage of CDK. Inferior iris depigmentation and atrophy was frequently observed among patients with CDK. 2007-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/closedAccess application/pdf spa http://pa.bibdigital.ucc.edu.ar/4021/1/A_UrretsZaval%C3%ADa_Knoll_Maccio_UrretsZaval%C3%ADa_Saad_Serra.pdf Urrets Zavalía, Julio ORCID: https://orcid.org/0000-0003-2267-2783 <https://orcid.org/0000-0003-2267-2783>, Maccio, J.Pablo, Knoll, Erna, Cafaro, Thamara, Urrets Zavalía, Enrique Alberto and Serra, Horacio M. ORCID: https://orcid.org/0000-0003-4979-8642 <https://orcid.org/0000-0003-4979-8642> (2007) Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy. Cornea, 26 (7). pp. 800-804. ISSN 0277-3740 info:eu-repo/semantics/altIdentifier/doi/10.1097/ICO.0b013e31806bef31
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic RE Oftalmología
spellingShingle RE Oftalmología
Urrets Zavalía, Julio
Maccio, J.Pablo
Knoll, Erna
Cafaro, Thamara
Urrets Zavalía, Enrique Alberto
Serra, Horacio M.
Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy
topic_facet RE Oftalmología
description PURPOSE: To present external eye findings and the observation of iris atrophy in patients with climatic droplet keratopathy (CDK). METHODS: Twenty-three patients with CDK and 13 controls living in a semideserted plain of the Argentine Patagonia were studied. Besides a comprehensive eye examination, Cochet-Bonnet aesthesiometry, Schirmer II test, breakup time (BUT), and surface staining were performed. According to corneal findings, eyes were grouped as grade 1 (confluent translucent microdroplets localized in the limbic region of the horizontal quadrants); grade 2 (band-shaped subepithelial haziness compromising the central cornea); and grade 3 (previously described lesions with yellow subepithelial droplets). Results were analyzed with the Fisher, Mann-Whitney, and Spearman tests, which were considered significant at P < 0.05. RESULTS: Nineteen of 23 patients with CDK had bilateral disease, which was asymmetric in 2 of them. Sixteen eyes had grade 1, 21 eyes had grade 2, and 5 eyes had grade 3 disease. Aesthesiometry showed that the more advanced the disease, the more profound the corneal hypoesthesia (P = 0.0008). BUT and ocular surface staining significantly differed between eyes with grade 3 and grade 1, grade 3 and grade 2, and grade 3 and controls. In 38.09% of eyes with CDK and in none of the controls, sectorial depigmentation and atrophy of the inferior iris were observed. CONCLUSIONS: A severe decrease of corneal sensitivity was observed in advanced stages of CDK. Some degree of dry eye was present in most patients, but severe disease was infrequent at any stage of CDK. Inferior iris depigmentation and atrophy was frequently observed among patients with CDK.
format Artículo
author Urrets Zavalía, Julio
Maccio, J.Pablo
Knoll, Erna
Cafaro, Thamara
Urrets Zavalía, Enrique Alberto
Serra, Horacio M.
author_facet Urrets Zavalía, Julio
Maccio, J.Pablo
Knoll, Erna
Cafaro, Thamara
Urrets Zavalía, Enrique Alberto
Serra, Horacio M.
author_sort Urrets Zavalía, Julio
title Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy
title_short Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy
title_full Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy
title_fullStr Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy
title_full_unstemmed Surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy
title_sort surface alterations, corneal hypoesthesia, and iris atrophy in patients with climatic droplet keratopathy
publishDate 2007
url http://pa.bibdigital.ucc.edu.ar/4021/1/A_UrretsZaval%C3%ADa_Knoll_Maccio_UrretsZaval%C3%ADa_Saad_Serra.pdf
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