Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies

This study was conducted to compare among the most recent generation of five screening tests licensed in Argentina, in order to evaluate which of the tests has the best sensitivity for detection of antibodies against hepatitis C virus (HCV). The tests analyzed were: Detect-HCV™ (3.0) Biochem ImmunoS...

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Detalles Bibliográficos
Autores principales: Re, Viviana Elizabeth, Gallego, Sandra Verónica, Treviño, Elena, Barbás, María Gabriela, Dominguez, Claudia, Elbarcha, Osvaldo César, Bepre, Héctor, Contigiani, Marta Silvia
Formato: Artículo acceptedVersion
Lenguaje:Español
Publicado: 2005
Materias:
R Medicina (General)
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/3990/1/A_Re_Gallego_Trevi%C3%B1o_Barb%C3%A1s_Dom%C3%ADnguez_Elbarcha_Bepre_Contigiani.pdf
Aporte de:
Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-3990
record_format dspace
spelling I38-R144-39902023-08-04T18:00:16Z http://pa.bibdigital.ucc.edu.ar/3990/ Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies Re, Viviana Elizabeth Gallego, Sandra Verónica Treviño, Elena Barbás, María Gabriela Dominguez, Claudia Elbarcha, Osvaldo César Bepre, Héctor Contigiani, Marta Silvia R Medicina (General) This study was conducted to compare among the most recent generation of five screening tests licensed in Argentina, in order to evaluate which of the tests has the best sensitivity for detection of antibodies against hepatitis C virus (HCV). The tests analyzed were: Detect-HCV™ (3.0) Biochem ImmunoSystems, Canada; Hepatitis C EIA Wiener Lab., Argentina; Equipar HCV Ab, Italy; Murex HCV 4.0, UK and Serodia-HCV particles agglutination test, Japan. The results obtained showed high discrepancy between the different kits used and show that some of the tests assessed have a low sensitivity for anti-HCV detection in both chronic infections and early seroconversion, and indicate that among the commercially available kits in Argentina, Murex HCV 4.0 (UK) and Serodia-HCV particles agglutination test (Japan) have the best sensitivity for HCV screening. Although the sensitivity of the assays is the first parameter to be considered for blood screening, more studies should be carried out to assess the specificity of such assays. 2005-05-31 application/pdf spa http://pa.bibdigital.ucc.edu.ar/3990/1/A_Re_Gallego_Trevi%C3%B1o_Barb%C3%A1s_Dom%C3%ADnguez_Elbarcha_Bepre_Contigiani.pdf Re, Viviana Elizabeth ORCID: https://orcid.org/0000-0002-4106-6642 <https://orcid.org/0000-0002-4106-6642>, Gallego, Sandra Verónica, Treviño, Elena, Barbás, María Gabriela, Dominguez, Claudia, Elbarcha, Osvaldo César, Bepre, Héctor and Contigiani, Marta Silvia ORCID: https://orcid.org/0000-0002-7171-0013 <https://orcid.org/0000-0002-7171-0013> (2005) Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies. Memorias do Instituto Oswaldo Cruz, 100 (3). pp. 303-307. ISSN 0074-0276 info:eu-repo/semantics/altIdentifier/doi/10.1590/S0074-02762005000300016 info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/acceptedVersion Fil: Re, Viviana Elizabeth. Instituto de Virología Dr. J. M. Vanella, Facultad de Ciencias Medicas, Ciudad Universitaria, (5016) Córdoba, Enfermera Gordillo Gómez s/n, Argentina Fil: Gallego, Sandra Verónica. Instituto de Virología Dr. J. M. Vanella, Facultad de Ciencias Medicas, Ciudad Universitaria, (5016) Córdoba, Enfermera Gordillo Gómez s/n, Argentina Fil: Treviño, Elena. Instituto de Hemoterapia Y Hematología, Universidad Nacional de Córdoba, Ciudad Universitaria, (5016) Córdoba, Enfermera Gordillo Gómez s/n, Argentina Fil: Barbás, María Gabriela. Instituto de Virología Dr. J. M. Vanella, Facultad de Ciencias Medicas, Ciudad Universitaria, (5016) Córdoba, Enfermera Gordillo Gómez s/n, Argentina Fil: Dominguez, Claudia. Instituto de Hemoterapia Y Hematología, Universidad Nacional de Córdoba, Ciudad Universitaria, (5016) Córdoba, Enfermera Gordillo Gómez s/n, Argentina Fil: Elbarcha, Osvaldo César. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina Fil: Bepre, Héctor. Instituto de Virología Dr. J. M. Vanella, Facultad de Ciencias Medicas, Ciudad Universitaria, (5016) Córdoba, Enfermera Gordillo Gómez s/n, Argentina Fil: Contigiani, Marta Silvia. Instituto de Virología Dr. J. M. Vanella, Facultad de Ciencias Medicas, Ciudad Universitaria, (5016) Córdoba, Enfermera Gordillo Gómez s/n, Argentina info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic R Medicina (General)
spellingShingle R Medicina (General)
Re, Viviana Elizabeth
Gallego, Sandra Verónica
Treviño, Elena
Barbás, María Gabriela
Dominguez, Claudia
Elbarcha, Osvaldo César
Bepre, Héctor
Contigiani, Marta Silvia
Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies
topic_facet R Medicina (General)
description This study was conducted to compare among the most recent generation of five screening tests licensed in Argentina, in order to evaluate which of the tests has the best sensitivity for detection of antibodies against hepatitis C virus (HCV). The tests analyzed were: Detect-HCV™ (3.0) Biochem ImmunoSystems, Canada; Hepatitis C EIA Wiener Lab., Argentina; Equipar HCV Ab, Italy; Murex HCV 4.0, UK and Serodia-HCV particles agglutination test, Japan. The results obtained showed high discrepancy between the different kits used and show that some of the tests assessed have a low sensitivity for anti-HCV detection in both chronic infections and early seroconversion, and indicate that among the commercially available kits in Argentina, Murex HCV 4.0 (UK) and Serodia-HCV particles agglutination test (Japan) have the best sensitivity for HCV screening. Although the sensitivity of the assays is the first parameter to be considered for blood screening, more studies should be carried out to assess the specificity of such assays.
format Artículo
Artículo
acceptedVersion
author Re, Viviana Elizabeth
Gallego, Sandra Verónica
Treviño, Elena
Barbás, María Gabriela
Dominguez, Claudia
Elbarcha, Osvaldo César
Bepre, Héctor
Contigiani, Marta Silvia
author_facet Re, Viviana Elizabeth
Gallego, Sandra Verónica
Treviño, Elena
Barbás, María Gabriela
Dominguez, Claudia
Elbarcha, Osvaldo César
Bepre, Héctor
Contigiani, Marta Silvia
author_sort Re, Viviana Elizabeth
title Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies
title_short Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies
title_full Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies
title_fullStr Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies
title_full_unstemmed Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies
title_sort evaluation of five screening tests licensed in argentina for detection of hepatitis c virus antibodies
publishDate 2005
url http://pa.bibdigital.ucc.edu.ar/3990/1/A_Re_Gallego_Trevi%C3%B1o_Barb%C3%A1s_Dom%C3%ADnguez_Elbarcha_Bepre_Contigiani.pdf
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