Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]

The aim of the present study was to investigate the presence of extended-spectrum β-lactamases (ESBL) in Klebsiella pneumoniae isolated at the "Hospital de Niños de Córdoba". The strains were collected from inpatients between January 1996 and July 2000. A total of 150 ESBL producer isolate...

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Detalles Bibliográficos
Autores principales:	Saka, H.A., Egea, M., Culasso, C., Rollan, R., Avaro, A., Carvajal, L.
Formato:	Artículo
Lenguaje:	Español
Publicado:	2003
Materias:	QD Química
Acceso en línea:	http://pa.bibdigital.ucc.edu.ar/3969/1/A_Saka_Egea_Culasso_Rollan_Avaro_Carvajal.pdf
Aporte de:	Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba

id	I38-R144-3969
record_format	dspace
spelling	I38-R144-39692025-04-14T19:28:25Z http://pa.bibdigital.ucc.edu.ar/3969/ Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina] Saka, H.A. Egea, M. Culasso, C. Rollan, R. Avaro, A. Carvajal, L. QD Química The aim of the present study was to investigate the presence of extended-spectrum β-lactamases (ESBL) in Klebsiella pneumoniae isolated at the "Hospital de Niños de Córdoba". The strains were collected from inpatients between January 1996 and July 2000. A total of 150 ESBL producer isolates were detected. During 1996 the prevalence of ESBL producer K. pneumoniae was 20%, but since 1998 the values have increased to approximately 60%. Phenotypic analysis such as isoelectric point (pl) and antibiotyping performed in 32 randomly selected isolates showed two different enzyme profiles: 81% had ESBL with pl=7.9 and preferential activity against cefotaxime, while 19% showed ESBL with pl=5.4 and preferential activity against ceftazidime. No isolates resistant to imipenem or ciprofloxacin were detected. Susceptibility to other antimicrobial agents varied, but resistance to gentamicin was strongly associated with ESBL producer isolates. Resistance determinants could be transferred to Escherichia coliby conjugation assays. 2003-12-31 info:eu-repo/semantics/article info:eu-repo/semantics/closedAccess application/pdf spa http://pa.bibdigital.ucc.edu.ar/3969/1/A_Saka_Egea_Culasso_Rollan_Avaro_Carvajal.pdf Saka, H.A., Egea, M., Culasso, C., Rollan, R., Avaro, A. and Carvajal, L. (2003) Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]. Revista Argentina de Microbiología, 35 (1). pp. 1-7. ISSN 0325-7541
institution	Universidad Católica de Córdoba
institution_str	I-38
repository_str	R-144
collection	Producción Académica Universidad Católica de Córdoba (UCCor)
language	Español
orig_language_str_mv	spa
topic	QD Química
spellingShingle	QD Química Saka, H.A. Egea, M. Culasso, C. Rollan, R. Avaro, A. Carvajal, L. Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]
topic_facet	QD Química
description	The aim of the present study was to investigate the presence of extended-spectrum β-lactamases (ESBL) in Klebsiella pneumoniae isolated at the "Hospital de Niños de Córdoba". The strains were collected from inpatients between January 1996 and July 2000. A total of 150 ESBL producer isolates were detected. During 1996 the prevalence of ESBL producer K. pneumoniae was 20%, but since 1998 the values have increased to approximately 60%. Phenotypic analysis such as isoelectric point (pl) and antibiotyping performed in 32 randomly selected isolates showed two different enzyme profiles: 81% had ESBL with pl=7.9 and preferential activity against cefotaxime, while 19% showed ESBL with pl=5.4 and preferential activity against ceftazidime. No isolates resistant to imipenem or ciprofloxacin were detected. Susceptibility to other antimicrobial agents varied, but resistance to gentamicin was strongly associated with ESBL producer isolates. Resistance determinants could be transferred to Escherichia coliby conjugation assays.
format	Artículo
author	Saka, H.A. Egea, M. Culasso, C. Rollan, R. Avaro, A. Carvajal, L.
author_facet	Saka, H.A. Egea, M. Culasso, C. Rollan, R. Avaro, A. Carvajal, L.
author_sort	Saka, H.A.
title	Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]
title_short	Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]
title_full	Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]
title_fullStr	Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]
title_full_unstemmed	Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]
title_sort	extended-spectrum β-lactamases in klebsiella pneumoniae isolated in a pediatric hospital of córdoba, argentina [β-lactamasas de espectro extendido en klebsiella pneumoniae aisladas en el hospital de niños de córdoba, argentina]
publishDate	2003
url	http://pa.bibdigital.ucc.edu.ar/3969/1/A_Saka_Egea_Culasso_Rollan_Avaro_Carvajal.pdf
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Extended-spectrum β-lactamases in Klebsiella pneumoniae isolated in a pediatric Hospital of Córdoba, Argentina [β-Lactamasas de espectro extendido en Klebsiella pneumoniae aisladas en el Hospital de Niños de Córdoba, Argentina]

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