Prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis

Background. The prognostic value of left ventricular dysfunction in patients with sepsis is unknown. Speckle tracking echocardiography (STE) is a novel, sensitive method for assessing ventricular function, capable of unmasking myocardial dysfunction not detected with conventional echocardiography. W...

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Autores principales: Ricarte Bratti, Juan Pablo, Brizuela, Nilda Yolanda, Urinovsky, Marcelo, Moreyra, Eduardo, Paredes, Sergio Guillermo, Vogliotti, Ignacio, Colque, Roberto, Tibaldi, Miguel Ángel
Formato: Artículo acceptedVersion
Lenguaje:Español
Publicado: Federación Argentina de Cardiología Argentina 2017
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Acceso en línea:http://pa.bibdigital.ucc.edu.ar/3517/1/A_RicarteBratti_Brizuela_Urinovsky_Moreyra_Paredes_Vogliotti_Colque_Tibaldi.pdf
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id I38-R144-3517
record_format dspace
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic R Medicina (General)
spellingShingle R Medicina (General)
Ricarte Bratti, Juan Pablo
Brizuela, Nilda Yolanda
Urinovsky, Marcelo
Moreyra, Eduardo
Paredes, Sergio Guillermo
Vogliotti, Ignacio
Colque, Roberto
Tibaldi, Miguel Ángel
Prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis
topic_facet R Medicina (General)
description Background. The prognostic value of left ventricular dysfunction in patients with sepsis is unknown. Speckle tracking echocardiography (STE) is a novel, sensitive method for assessing ventricular function, capable of unmasking myocardial dysfunction not detected with conventional echocardiography. We assessed STE in patients with sepsis to determine whether it is associated with mortality. Material and methods. Between April 2015 and March 2016, patients aged ≥18 years admitted to the intensive care unit with the diagnosis of sepsis and without previous cardiomyopathy were prospectively imaged using transthoracic echocardiography. Left ventricular function was assessed using conventional methods and STE. Mortality was assessed over 30 days. Results. Eighteen patients were included and the 30-day mortality rate was 27.7%. The ejection fraction (EF) estimated using the Simpson method was similar between patients who died and those who survived; however, the ventricular function determined using STE in the 4-chamber view was significantly lower in patients who died (-14% ± 5 vs -17% ± 2, p=0.028). No significant differences were observed in the 2-chamber view (alive: -16 ± 3, dead: -14 ± 5, p=0.182), long apical axes view (alive: -17 ± 2, dead: -15 ± 4, p=0.434) or global strain (alive: -17 ± 2, dead: -14 ± 4, p=0.118). Conclusion. In patients with sepsis, ventricular function assessed with STE in the 4-chamber view was more sensitive than EF in detecting dysfunction and better predicted 30-day mortality. Larger trials will be necessary to corroborate these findings. Insuf Card 2017; 12(1): 2-8.
format Artículo
Artículo
acceptedVersion
author Ricarte Bratti, Juan Pablo
Brizuela, Nilda Yolanda
Urinovsky, Marcelo
Moreyra, Eduardo
Paredes, Sergio Guillermo
Vogliotti, Ignacio
Colque, Roberto
Tibaldi, Miguel Ángel
author_facet Ricarte Bratti, Juan Pablo
Brizuela, Nilda Yolanda
Urinovsky, Marcelo
Moreyra, Eduardo
Paredes, Sergio Guillermo
Vogliotti, Ignacio
Colque, Roberto
Tibaldi, Miguel Ángel
author_sort Ricarte Bratti, Juan Pablo
title Prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis
title_short Prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis
title_full Prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis
title_fullStr Prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis
title_full_unstemmed Prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis
title_sort prognostic value of ventricular function assessed by speckle tracking echocardiography in patients with sepsis
publisher Federación Argentina de Cardiología Argentina
publishDate 2017
url http://pa.bibdigital.ucc.edu.ar/3517/1/A_RicarteBratti_Brizuela_Urinovsky_Moreyra_Paredes_Vogliotti_Colque_Tibaldi.pdf
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