Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]

Metabolic syndrome (MS) is a global health problem. Dietary factors, especially fatty acids, may affect MS pathology. However, the associations between omega-3 polyunsaturated fatty acids (n-3 PUFAs) and MS risk demonstrate inconsistent results. To clarify the relationship between dietary n-3 PUFA a...

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Detalles Bibliográficos
Autores principales: Bertorello, Natalia Belén dir., Eynard, Aldo R., Defagó, María Daniela
Formato: Artículo
Lenguaje:Español
Publicado: Sociedad Chilena de Nutricion Bromatologia y Toxilogica 2022
Materias:
Q Ciencia (General)
R Medicina (General)
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/3244/1/A_Bertorello_Eynard_Defago.pdf
Aporte de:
Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
Descripción
Sumario:Metabolic syndrome (MS) is a global health problem. Dietary factors, especially fatty acids, may affect MS pathology. However, the associations between omega-3 polyunsaturated fatty acids (n-3 PUFAs) and MS risk demonstrate inconsistent results. To clarify the relationship between dietary n-3 PUFA and endothelial function on MS, we carried out a systematic review. An electronic literature search based on controlled clinical trials (CCTs) between 2004 and 2020 was conducted. A total of 28 articles were included in the systematic review. Studies were analyzed according intervention type: dietary interventions (12 CCTs), dietary supplementation interventions (9 CCTs) and mixed interventions (7 CCTs). Studies with dietary interventions characterized by n-3 PUFAs increased by food source, such as Mediterranean and Nordic-style diets, reported significant reduction in systolic and diastolic blood pressure, and also in inflammatory endothelial biomarkers. The same effect was also observed in mixed interventions and in CCTs with n-3 PUFAs supple-mentation. Dietary interventions with n-3 PUFAs contributes to improved endothelial and cardiovascular health in SM and associated risk factors.

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