Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]

Metabolic syndrome (MS) is a global health problem. Dietary factors, especially fatty acids, may affect MS pathology. However, the associations between omega-3 polyunsaturated fatty acids (n-3 PUFAs) and MS risk demonstrate inconsistent results. To clarify the relationship between dietary n-3 PUFA a...

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Detalles Bibliográficos
Autores principales:	Bertorello, Natalia Belén dir., Eynard, Aldo R., Defagó, María Daniela
Formato:	Artículo
Lenguaje:	Español
Publicado:	Sociedad Chilena de Nutricion Bromatologia y Toxilogica 2022
Materias:	Q Ciencia (General) R Medicina (General)
Acceso en línea:	http://pa.bibdigital.ucc.edu.ar/3244/1/A_Bertorello_Eynard_Defago.pdf
Aporte de:	Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba

id	I38-R144-3244
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spelling	I38-R144-32442025-04-07T19:37:30Z http://pa.bibdigital.ucc.edu.ar/3244/ Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática] Bertorello, Natalia Belén dir. Eynard, Aldo R. Defagó, María Daniela Q Ciencia (General) R Medicina (General) Metabolic syndrome (MS) is a global health problem. Dietary factors, especially fatty acids, may affect MS pathology. However, the associations between omega-3 polyunsaturated fatty acids (n-3 PUFAs) and MS risk demonstrate inconsistent results. To clarify the relationship between dietary n-3 PUFA and endothelial function on MS, we carried out a systematic review. An electronic literature search based on controlled clinical trials (CCTs) between 2004 and 2020 was conducted. A total of 28 articles were included in the systematic review. Studies were analyzed according intervention type: dietary interventions (12 CCTs), dietary supplementation interventions (9 CCTs) and mixed interventions (7 CCTs). Studies with dietary interventions characterized by n-3 PUFAs increased by food source, such as Mediterranean and Nordic-style diets, reported significant reduction in systolic and diastolic blood pressure, and also in inflammatory endothelial biomarkers. The same effect was also observed in mixed interventions and in CCTs with n-3 PUFAs supple-mentation. Dietary interventions with n-3 PUFAs contributes to improved endothelial and cardiovascular health in SM and associated risk factors. Sociedad Chilena de Nutricion Bromatologia y Toxilogica 2022-02 info:eu-repo/semantics/article info:eu-repo/semantics/closedAccess application/pdf spa http://pa.bibdigital.ucc.edu.ar/3244/1/A_Bertorello_Eynard_Defago.pdf Bertorello, Natalia Belén dir. ORCID: https://orcid.org/0000-0002-6768-0122 <https://orcid.org/0000-0002-6768-0122>, Eynard, Aldo R. ORCID: https://orcid.org/0000-0002-0366-3112 <https://orcid.org/0000-0002-0366-3112> and Defagó, María Daniela ORCID: https://orcid.org/0000-0002-8878-3067 <https://orcid.org/0000-0002-8878-3067> (2022) Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]. Revista Chilena de Nutricion, 49 (1). pp. 133-146. ISSN 0717-7518 https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182022000100133&lng=en&nrm=iso&tlng=en info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.4067/S0717-7518202200010013
institution	Universidad Católica de Córdoba
institution_str	I-38
repository_str	R-144
collection	Producción Académica Universidad Católica de Córdoba (UCCor)
language	Español
orig_language_str_mv	spa
topic	Q Ciencia (General) R Medicina (General)
spellingShingle	Q Ciencia (General) R Medicina (General) Bertorello, Natalia Belén dir. Eynard, Aldo R. Defagó, María Daniela Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]
topic_facet	Q Ciencia (General) R Medicina (General)
description	Metabolic syndrome (MS) is a global health problem. Dietary factors, especially fatty acids, may affect MS pathology. However, the associations between omega-3 polyunsaturated fatty acids (n-3 PUFAs) and MS risk demonstrate inconsistent results. To clarify the relationship between dietary n-3 PUFA and endothelial function on MS, we carried out a systematic review. An electronic literature search based on controlled clinical trials (CCTs) between 2004 and 2020 was conducted. A total of 28 articles were included in the systematic review. Studies were analyzed according intervention type: dietary interventions (12 CCTs), dietary supplementation interventions (9 CCTs) and mixed interventions (7 CCTs). Studies with dietary interventions characterized by n-3 PUFAs increased by food source, such as Mediterranean and Nordic-style diets, reported significant reduction in systolic and diastolic blood pressure, and also in inflammatory endothelial biomarkers. The same effect was also observed in mixed interventions and in CCTs with n-3 PUFAs supple-mentation. Dietary interventions with n-3 PUFAs contributes to improved endothelial and cardiovascular health in SM and associated risk factors.
format	Artículo
author	Bertorello, Natalia Belén dir. Eynard, Aldo R. Defagó, María Daniela
author_facet	Bertorello, Natalia Belén dir. Eynard, Aldo R. Defagó, María Daniela
author_sort	Bertorello, Natalia Belén dir.
title	Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]
title_short	Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]
title_full	Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]
title_fullStr	Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]
title_full_unstemmed	Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]
title_sort	dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: a systematic review[ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: una revisión sistemática]
publisher	Sociedad Chilena de Nutricion Bromatologia y Toxilogica
publishDate	2022
url	http://pa.bibdigital.ucc.edu.ar/3244/1/A_Bertorello_Eynard_Defago.pdf
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Dietary n-3 polyunsaturated fatty acids improve endothelial markers in metabolic syndrome: A systematic review[Ácidos grasos dietarios poliinsaturados n-3 mejoran los marcadores endoteliales en el síndrome metabólico: Una revisión sistemática]

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