Influencia del zinc administrado a pacientes críticos con nutrición parenteral sobre los niveles de zinc plasmático, proteína C reactiva, interleuquina-6 y receptor soluble de interleuquina-6 - Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive c protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients.

Objectives:To study the interrelationship between serum Interleukin-6 (IL-6), serum Interleukin-6 soluble Receptor (IL-6 sR), C-Reactive Protein (C-RP), plasma-tic Zinc levels (PlZn) and their response in relation to Zn administered by TPN, in critical patients. Methods: 17 patients, receiving...

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Autores principales: Menéndez, Ana M., De Portela, M. L., Weisstaub, A., Montemerlo, H., Guidoni, M. E., Rusí, F., Zeni, S.
Formato: Artículo
Lenguaje:Español
Publicado: Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación 2014
Materias:
Zinc
pacientes críticos con nutrición parenteral
Interleuquina-6
Receptor soluble de interleu-quina-6
Critically ill patients with parenteral nutrition
Interleukin-6
Soluble receptor of interleukin-6
C reactive protein
proteína C reactiva
Acceso en línea:http://repositorio.ub.edu.ar/handle/123456789/2765
Aporte de:
Repositorio Institucional - Universidad de Belgrano (UB) de Universidad de Belgrano
id I36-R142-123456789-2765
record_format dspace
institution Universidad de Belgrano
institution_str I-36
repository_str R-142
collection Repositorio Institucional - Universidad de Belgrano (UB)
language Español
topic Zinc
pacientes críticos con nutrición parenteral
Interleuquina-6
Receptor soluble de interleu-quina-6
Critically ill patients with parenteral nutrition
Interleukin-6
Soluble receptor of interleukin-6
C reactive protein
proteína C reactiva
spellingShingle Zinc
pacientes críticos con nutrición parenteral
Interleuquina-6
Receptor soluble de interleu-quina-6
Critically ill patients with parenteral nutrition
Interleukin-6
Soluble receptor of interleukin-6
C reactive protein
proteína C reactiva
Menéndez, Ana M.
De Portela, M. L.
Weisstaub, A.
Montemerlo, H.
Guidoni, M. E.
Rusí, F.
Zeni, S.
Influencia del zinc administrado a pacientes críticos con nutrición parenteral sobre los niveles de zinc plasmático, proteína C reactiva, interleuquina-6 y receptor soluble de interleuquina-6 - Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive c protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients.
topic_facet Zinc
pacientes críticos con nutrición parenteral
Interleuquina-6
Receptor soluble de interleu-quina-6
Critically ill patients with parenteral nutrition
Interleukin-6
Soluble receptor of interleukin-6
C reactive protein
proteína C reactiva
description Objectives:To study the interrelationship between serum Interleukin-6 (IL-6), serum Interleukin-6 soluble Receptor (IL-6 sR), C-Reactive Protein (C-RP), plasma-tic Zinc levels (PlZn) and their response in relation to Zn administered by TPN, in critical patients. Methods: 17 patients, receiving TPN as a consequence of acute pancreatitis (n = 4) or after a major abdominal surgery due to intestinal cancer (n = 7), intestinal fístula (n = 3), intes-tinal obstruction (n = 2) or intestinal íleus (n = 1) were stu-died. At the beginning (To) and at the end of the TPN admi-nistration (6-21days) serum IL-6 and IL-6 sR were determined by ELISA; C-RP ultrasensitive (C-RP us) by inmunoturbidimetric method; Zn was determined in TPN and in plasma by Atomic Absorption Spectrometry. Charac-teristics of the patients were (mean ± SD and ranges): age: 60.6 ± 11.7 (37-77) years; BMI (kg/m 2 ): 26.0 ± 3.4 (19.9-34.0). Results:The results (mean ± standard deviation and ran-ges) were: Zn provided by TPN (mg/d): 6.1 ± 2.0 (range 2.8 to 10.8). Biochemical levels were, at To and Tf, respectively: (mean±SD and ranges) were at To y Tf, respectively: Zn Pl (μg/dl): 104 ± 46 (35-177); 120 ± 55 (52-229); IL-6 (pg/mL) 93 ± 74 (10-262); 117 ± 180 (7-761); IL6sR (pg/mL): 1,012 ± 322 (589-1855); 1,269 ± 451 (631-2195); C-RP us (mg/L): 71 ± 63 (2-196); 65 ± 43 (0-137). There was no correlation between variations of IL6, IL6sR, C-RP, PlZn levels and the daily amount of Zn administered in the TPN mixtures. Two patients presented a bad evolution; they received 4.2 and 5.2 md/d of Zn and showed an increase of IL6 levels, maintained high levels of IL6sR but C-RP levels decreased Conclusions:the range of 2.8 to 10.8 mg/d of Zn admi-nistered in TPN mixtures did not exacerbate the inflam-matory response
format Article
author Menéndez, Ana M.
De Portela, M. L.
Weisstaub, A.
Montemerlo, H.
Guidoni, M. E.
Rusí, F.
Zeni, S.
author_facet Menéndez, Ana M.
De Portela, M. L.
Weisstaub, A.
Montemerlo, H.
Guidoni, M. E.
Rusí, F.
Zeni, S.
author_sort Menéndez, Ana M.
title Influencia del zinc administrado a pacientes críticos con nutrición parenteral sobre los niveles de zinc plasmático, proteína C reactiva, interleuquina-6 y receptor soluble de interleuquina-6 - Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive c protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients.
title_short Influencia del zinc administrado a pacientes críticos con nutrición parenteral sobre los niveles de zinc plasmático, proteína C reactiva, interleuquina-6 y receptor soluble de interleuquina-6 - Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive c protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients.
title_full Influencia del zinc administrado a pacientes críticos con nutrición parenteral sobre los niveles de zinc plasmático, proteína C reactiva, interleuquina-6 y receptor soluble de interleuquina-6 - Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive c protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients.
title_fullStr Influencia del zinc administrado a pacientes críticos con nutrición parenteral sobre los niveles de zinc plasmático, proteína C reactiva, interleuquina-6 y receptor soluble de interleuquina-6 - Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive c protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients.
title_full_unstemmed Influencia del zinc administrado a pacientes críticos con nutrición parenteral sobre los niveles de zinc plasmático, proteína C reactiva, interleuquina-6 y receptor soluble de interleuquina-6 - Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive c protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients.
title_sort influencia del zinc administrado a pacientes críticos con nutrición parenteral sobre los niveles de zinc plasmático, proteína c reactiva, interleuquina-6 y receptor soluble de interleuquina-6 - influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive c protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients.
publisher Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación
publishDate 2014
url http://repositorio.ub.edu.ar/handle/123456789/2765
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