Understanding the Process ofEnvelope Glycoprotein Incorporation into Virions in Simian and Feline Immunodeficiency Viruses

The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis. Therefore, Env incorporation into the virions formed by assembly of the viral Gag polyprotein at the plasma me...

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Autores principales:	Affranchino, José L., González, Silvia A.
Formato:	Artículo
Lenguaje:	Inglés
Publicado:	Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación 2014
Materias:	Simian immunodeficiency virus feline immunodeficiency virus Gag polyprotein envelope glycoprotein glicoproteína de la envoltura poliproteína Gag virus de la inmunodeficiencia felina Virus de la inmunodeficiencia del simio
Acceso en línea:	http://repositorio.ub.edu.ar/handle/123456789/2718
Aporte de:	Repositorio Institucional - Universidad de Belgrano (UB) de Universidad de Belgrano

id	I36-R142-123456789-2718
record_format	dspace
institution	Universidad de Belgrano
institution_str	I-36
repository_str	R-142
collection	Repositorio Institucional - Universidad de Belgrano (UB)
language	Inglés
topic	Simian immunodeficiency virus feline immunodeficiency virus Gag polyprotein envelope glycoprotein glicoproteína de la envoltura poliproteína Gag virus de la inmunodeficiencia felina Virus de la inmunodeficiencia del simio
spellingShingle	Simian immunodeficiency virus feline immunodeficiency virus Gag polyprotein envelope glycoprotein glicoproteína de la envoltura poliproteína Gag virus de la inmunodeficiencia felina Virus de la inmunodeficiencia del simio Affranchino, José L. González, Silvia A. Understanding the Process ofEnvelope Glycoprotein Incorporation into Virions in Simian and Feline Immunodeficiency Viruses
topic_facet	Simian immunodeficiency virus feline immunodeficiency virus Gag polyprotein envelope glycoprotein glicoproteína de la envoltura poliproteína Gag virus de la inmunodeficiencia felina Virus de la inmunodeficiencia del simio
description	The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis. Therefore, Env incorporation into the virions formed by assembly of the viral Gag polyprotein at the plasma membrane of the infected cells is a key step in the replication cycle of lentiviruses. Besides being usefulmodels of human immunodeficiency virus (HIV) infections in humans and valuable tools for developing AIDS therapies and vaccines, simian and feline immunodeficiency viruses (SIV and FIV, respectively) are relevant animal retroviruses; the study of which provides important information on how lentiviral replication strategies have evolved. In this review, we discuss the molecular mechanisms underlying the incorporation of the SIV and FIV Env glycoproteins into viral particles.
format	Article
author	Affranchino, José L. González, Silvia A.
author_facet	Affranchino, José L. González, Silvia A.
author_sort	Affranchino, José L.
title	Understanding the Process ofEnvelope Glycoprotein Incorporation into Virions in Simian and Feline Immunodeficiency Viruses
title_short	Understanding the Process ofEnvelope Glycoprotein Incorporation into Virions in Simian and Feline Immunodeficiency Viruses
title_full	Understanding the Process ofEnvelope Glycoprotein Incorporation into Virions in Simian and Feline Immunodeficiency Viruses
title_fullStr	Understanding the Process ofEnvelope Glycoprotein Incorporation into Virions in Simian and Feline Immunodeficiency Viruses
title_full_unstemmed	Understanding the Process ofEnvelope Glycoprotein Incorporation into Virions in Simian and Feline Immunodeficiency Viruses
title_sort	understanding the process ofenvelope glycoprotein incorporation into virions in simian and feline immunodeficiency viruses
publisher	Universidad de Belgrano - Facultad de Ciencias Exactas y Naturales - Proyectos de Investigación
publishDate	2014
url	http://repositorio.ub.edu.ar/handle/123456789/2718
work_keys_str_mv	AT affranchinojosel understandingtheprocessofenvelopeglycoproteinincorporationintovirionsinsimianandfelineimmunodeficiencyviruses AT gonzalezsilviaa understandingtheprocessofenvelopeglycoproteinincorporationintovirionsinsimianandfelineimmunodeficiencyviruses
bdutipo_str	Repositorios
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Understanding the Process ofEnvelope Glycoprotein Incorporation into Virions in Simian and Feline Immunodeficiency Viruses

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