TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice

Abstract: Canonical transient receptor potential (TRPC) channels constitute a family of cation channels that exhibit a regional and cell-specific expression pattern throughout the brain. It has been reported previously that TRPC3 channels are effectors of the brain-derived neurotrophic factor (BDNF)...

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Detalles Bibliográficos
Autores principales: Phelan, Kevin D., Shwe, U Thaung, Cozart, Michael A., Wu, Hong, Mock, Matthew M., Abramowitz, Joel, Birnbaumer, Lutz, Zheng, Fang
Formato: Artículo
Lenguaje:Inglés
Publicado: Wiley 2019
Materias:
ELECTROENCEFALOGRAFIA
NEURONAS
ANALISIS ESPECTRAL
SISTEMA NERVIOSO
MEDICAMENTOS
EPILEPSIA
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/8738
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139123456789-8738
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic ELECTROENCEFALOGRAFIA
NEURONAS
ANALISIS ESPECTRAL
SISTEMA NERVIOSO
MEDICAMENTOS
EPILEPSIA
spellingShingle ELECTROENCEFALOGRAFIA
NEURONAS
ANALISIS ESPECTRAL
SISTEMA NERVIOSO
MEDICAMENTOS
EPILEPSIA
Phelan, Kevin D.
Shwe, U Thaung
Cozart, Michael A.
Wu, Hong
Mock, Matthew M.
Abramowitz, Joel
Birnbaumer, Lutz
Zheng, Fang
TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
topic_facet ELECTROENCEFALOGRAFIA
NEURONAS
ANALISIS ESPECTRAL
SISTEMA NERVIOSO
MEDICAMENTOS
EPILEPSIA
description Abstract: Canonical transient receptor potential (TRPC) channels constitute a family of cation channels that exhibit a regional and cell-specific expression pattern throughout the brain. It has been reported previously that TRPC3 channels are effectors of the brain-derived neurotrophic factor (BDNF)/trkB signaling pathway. Given the long postulated role of BDNF in epileptogenesis, TRPC3 channels may be a critical component in the underlying pathophysiology of seizure and epilepsy. In this study, we investigated the precise role of TRPC3 channels in pilocarpine-induced status epilepticus (SE).
format Artículo
author Phelan, Kevin D.
Shwe, U Thaung
Cozart, Michael A.
Wu, Hong
Mock, Matthew M.
Abramowitz, Joel
Birnbaumer, Lutz
Zheng, Fang
author_facet Phelan, Kevin D.
Shwe, U Thaung
Cozart, Michael A.
Wu, Hong
Mock, Matthew M.
Abramowitz, Joel
Birnbaumer, Lutz
Zheng, Fang
author_sort Phelan, Kevin D.
title TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
title_short TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
title_full TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
title_fullStr TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
title_full_unstemmed TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
title_sort trpc3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice
publisher Wiley
publishDate 2019
url https://repositorio.uca.edu.ar/handle/123456789/8738
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