A NOX4/TRPC6 pathway in podocyte calcium pegulation and renal damage in diabetic kidney disease

Abstract: Background: Loss of glomerular podocytes is an indicator of diabetic kidney disease (DKD). The damage to these cells has been attributed in part to elevated intrarenal oxidative stress. The primary source of the renal reactive oxygen species, particularly H2O2, is NADPH oxidase 4 (NOX4). W...

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Detalles Bibliográficos
Autores principales: Ilatovskaya, Daria V., Blass, Gregory, Palygin, Oleg, Levchenko, Vladislav, Pavlov, Tengis S., Grzybowski, Michael N., Winsor, Kristen, Shuyskiy, Leonid S., Geurts, Aron M., Cowley, Allen W., Birnbaumer, Lutz, Staruschenko, Alexander
Formato: Artículo
Lenguaje:Inglés
Publicado: American Society of Nephrology 2019
Materias:
CALCIO
NEFROLOGIA
RIÑON
PROTEINAS
ENFERMEDADES RENALES
GENES
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/8693
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina

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