Thermodynamics of a model for RNA folding

Abstract: We analyze the thermodynamic properties of a simplified model for folded RNA molecules recently studied by G. Vernizzi, H. Orland, A. Zee (in Phys. Rev. Lett. 94 (2005) 168103). The model consists of a chain of one-flavor base molecules with a flexible backbone and all possible pairing int...

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Autores principales: Dell'Erba, Matías G., Zemba, Guillermo Raúl
Formato: Documento de trabajo
Lenguaje:Inglés
Publicado: 2019
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/5492
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id I33-R139123456789-5492
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic MOLECULAS DE ARN
PROPIEDADES TERMODINAMICAS
Vernizzi, Graziano
Zee, Anthony
Orland, Henri
BIOLOGIA
DIAGRAMA DE FEYNMAN
spellingShingle MOLECULAS DE ARN
PROPIEDADES TERMODINAMICAS
Vernizzi, Graziano
Zee, Anthony
Orland, Henri
BIOLOGIA
DIAGRAMA DE FEYNMAN
Dell'Erba, Matías G.
Zemba, Guillermo Raúl
Thermodynamics of a model for RNA folding
topic_facet MOLECULAS DE ARN
PROPIEDADES TERMODINAMICAS
Vernizzi, Graziano
Zee, Anthony
Orland, Henri
BIOLOGIA
DIAGRAMA DE FEYNMAN
description Abstract: We analyze the thermodynamic properties of a simplified model for folded RNA molecules recently studied by G. Vernizzi, H. Orland, A. Zee (in Phys. Rev. Lett. 94 (2005) 168103). The model consists of a chain of one-flavor base molecules with a flexible backbone and all possible pairing interactions equally allowed. The spatial pseudoknot structure of the model can be effi- ciently studied by introducing a N × N hermitian random matrix model at each chain site, and associating Feynman diagrams of these models to spatial configurations of the molecules. We obtain an exact expression for the topo- logical expansion of the partition function of the system. We calculate exact and asymptotic expressions for the free energy, specific heat, entanglement and chemical potential and study their behavior as a function of temperature. Our results are consistent with the interpretation of 1/N as being a measure of the concentration of Mg++ in solution.
format Documento de trabajo
author Dell'Erba, Matías G.
Zemba, Guillermo Raúl
author_facet Dell'Erba, Matías G.
Zemba, Guillermo Raúl
author_sort Dell'Erba, Matías G.
title Thermodynamics of a model for RNA folding
title_short Thermodynamics of a model for RNA folding
title_full Thermodynamics of a model for RNA folding
title_fullStr Thermodynamics of a model for RNA folding
title_full_unstemmed Thermodynamics of a model for RNA folding
title_sort thermodynamics of a model for rna folding
publishDate 2019
url https://repositorio.uca.edu.ar/handle/123456789/5492
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AT zembaguillermoraul thermodynamicsofamodelforrnafolding
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