Melatonin, immune function and cancer
Abstract: Melatonin is a natural substance ubiquitous in distribution and present in almost all species ranging from unicellular organisms to humans. In mammals, melatonin is synthesized not only in the pineal gland but also in many other parts of the body, including the eyes, bone marrow, gastroint...
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| Autores principales: | , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés Inglés |
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Bentham Science
2019
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| Acceso en línea: | https://repositorio.uca.edu.ar/handle/123456789/1627 |
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I33-R139123456789-1627 |
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dspace |
| institution |
Universidad Católica Argentina |
| institution_str |
I-33 |
| repository_str |
R-139 |
| collection |
Repositorio Institucional de la Universidad Católica Argentina (UCA) |
| language |
Inglés Inglés |
| topic |
MELATONINA MELANOMA ESTRES OXIDATIVO NEOPLASIAS DE LA MAMA NEOPLASIAS DEL COLON NEOPLASIAS DEL SISTEMA DIGESTIVO LINFOCITOS T COLABORADORES CANCER |
| spellingShingle |
MELATONINA MELANOMA ESTRES OXIDATIVO NEOPLASIAS DE LA MAMA NEOPLASIAS DEL COLON NEOPLASIAS DEL SISTEMA DIGESTIVO LINFOCITOS T COLABORADORES CANCER Srinivasan, Venkataramanujan Pandi Perumal, Seithikurippu R. Brzezinski, Amnon Bhatnagar, Kunwar P. Cardinali, Daniel Pedro Melatonin, immune function and cancer |
| topic_facet |
MELATONINA MELANOMA ESTRES OXIDATIVO NEOPLASIAS DE LA MAMA NEOPLASIAS DEL COLON NEOPLASIAS DEL SISTEMA DIGESTIVO LINFOCITOS T COLABORADORES CANCER |
| description |
Abstract: Melatonin is a natural substance ubiquitous in distribution and present in almost all species ranging from unicellular organisms to humans. In mammals, melatonin is synthesized not only in the pineal gland but also in many other parts of the body, including the eyes, bone marrow, gastrointestinal tract, skin and lymphocytes. Melatonin influences almost every cell and can be traced in membrane, cytoplasmic, mitochondrial and nuclear compartments of the cell. The decline in the production of melatonin with age has been suggested as one of the major contributors to immunosenescence and development of neoplastic diseases. Melatonin is a natural antioxidant with immunoenhancing properties. T‐helper cells play an important role for protection against malignancy and melatonin has been shown to enhance T‐helper cell response by releasing interleukin‐2, interleukin‐10 and interferon‐γ. Melatonin is effective in suppressing neoplastic growth in a variety of tumors like melanoma, breast cancer and ovarian and colorectal cancer. As an adjuvant therapy, melatonin can be beneficial in treating patients suffering from breast cancer, hepatocellular carcinoma or melanoma. |
| format |
Artículo |
| author |
Srinivasan, Venkataramanujan Pandi Perumal, Seithikurippu R. Brzezinski, Amnon Bhatnagar, Kunwar P. Cardinali, Daniel Pedro |
| author_facet |
Srinivasan, Venkataramanujan Pandi Perumal, Seithikurippu R. Brzezinski, Amnon Bhatnagar, Kunwar P. Cardinali, Daniel Pedro |
| author_sort |
Srinivasan, Venkataramanujan |
| title |
Melatonin, immune function and cancer |
| title_short |
Melatonin, immune function and cancer |
| title_full |
Melatonin, immune function and cancer |
| title_fullStr |
Melatonin, immune function and cancer |
| title_full_unstemmed |
Melatonin, immune function and cancer |
| title_sort |
melatonin, immune function and cancer |
| publisher |
Bentham Science |
| publishDate |
2019 |
| url |
https://repositorio.uca.edu.ar/handle/123456789/1627 |
| work_keys_str_mv |
AT srinivasanvenkataramanujan melatoninimmunefunctionandcancer AT pandiperumalseithikurippur melatoninimmunefunctionandcancer AT brzezinskiamnon melatoninimmunefunctionandcancer AT bhatnagarkunwarp melatoninimmunefunctionandcancer AT cardinalidanielpedro melatoninimmunefunctionandcancer |
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Repositorios |
| _version_ |
1764820525749633025 |