Measurement of melatonin in body fluids : standards, protocols, and procedures

Abstract: The circadian rhythm of melatonin in saliva or plasma, or of the melatonin metabolite 6‐ sulphatoxymelatonin in urine, is a defining feature of suprachiasmatic nucleus function, the endogenous oscillatory pacemaker. These measurements are useful to evaluate problems related to the onset or...

Descripción completa

Detalles Bibliográficos
Autores principales: Alves de Almeida, Eduardo, Di Mascio, Paolo, Harumi, Tatsuo, Moscovitch, Adam, Hardeland, Rüdiger, Cardinali, Daniel Pedro, Brown, Gregory M., Pandi Perumal, Seithikurippu R.
Formato: Artículo
Lenguaje:Inglés
Inglés
Publicado: Springer 2019
Materias:
MELATONINA
RITMO CIRCADIANO
ELECTROFORESIS CAPILAR
ESPECTOMETRIA DE MASAS
RADIOINMUNOENSAYO
CROMATOGRAFIA LIQUIDA
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/1610
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139123456789-1610
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
Inglés
topic MELATONINA
RITMO CIRCADIANO
ELECTROFORESIS CAPILAR
ESPECTOMETRIA DE MASAS
RADIOINMUNOENSAYO
CROMATOGRAFIA LIQUIDA
spellingShingle MELATONINA
RITMO CIRCADIANO
ELECTROFORESIS CAPILAR
ESPECTOMETRIA DE MASAS
RADIOINMUNOENSAYO
CROMATOGRAFIA LIQUIDA
Alves de Almeida, Eduardo
Di Mascio, Paolo
Harumi, Tatsuo
Moscovitch, Adam
Hardeland, Rüdiger
Cardinali, Daniel Pedro
Brown, Gregory M.
Pandi Perumal, Seithikurippu R.
Measurement of melatonin in body fluids : standards, protocols, and procedures
topic_facet MELATONINA
RITMO CIRCADIANO
ELECTROFORESIS CAPILAR
ESPECTOMETRIA DE MASAS
RADIOINMUNOENSAYO
CROMATOGRAFIA LIQUIDA
description Abstract: The circadian rhythm of melatonin in saliva or plasma, or of the melatonin metabolite 6‐ sulphatoxymelatonin in urine, is a defining feature of suprachiasmatic nucleus function, the endogenous oscillatory pacemaker. These measurements are useful to evaluate problems related to the onset or offset of sleep and for assessing phase delays or advances of rhythms in entrained individuals. Additionally, they have become an important tool for psychiatric diagnosis, its use being recommended for phase typing in patients suffering from sleep and mood disorders. Thus, the development of sensitive and selective methods for the precise detection of melatonin in tissues and fluids of animals emerges as necessary. Due to its low concentration and the co‐existence of many other endogenous compounds in blood, the determination of melatonin has been an analytical challenge. This review discusses current methodologies employed for detection and quantification of melatonin in biological fluids and tissues.
format Artículo
author Alves de Almeida, Eduardo
Di Mascio, Paolo
Harumi, Tatsuo
Moscovitch, Adam
Hardeland, Rüdiger
Cardinali, Daniel Pedro
Brown, Gregory M.
Pandi Perumal, Seithikurippu R.
author_facet Alves de Almeida, Eduardo
Di Mascio, Paolo
Harumi, Tatsuo
Moscovitch, Adam
Hardeland, Rüdiger
Cardinali, Daniel Pedro
Brown, Gregory M.
Pandi Perumal, Seithikurippu R.
author_sort Alves de Almeida, Eduardo
title Measurement of melatonin in body fluids : standards, protocols, and procedures
title_short Measurement of melatonin in body fluids : standards, protocols, and procedures
title_full Measurement of melatonin in body fluids : standards, protocols, and procedures
title_fullStr Measurement of melatonin in body fluids : standards, protocols, and procedures
title_full_unstemmed Measurement of melatonin in body fluids : standards, protocols, and procedures
title_sort measurement of melatonin in body fluids : standards, protocols, and procedures
publisher Springer
publishDate 2019
url https://repositorio.uca.edu.ar/handle/123456789/1610
work_keys_str_mv AT alvesdealmeidaeduardo measurementofmelatonininbodyfluidsstandardsprotocolsandprocedures
AT dimasciopaolo measurementofmelatonininbodyfluidsstandardsprotocolsandprocedures
AT harumitatsuo measurementofmelatonininbodyfluidsstandardsprotocolsandprocedures
AT moscovitchadam measurementofmelatonininbodyfluidsstandardsprotocolsandprocedures
AT hardelandrudiger measurementofmelatonininbodyfluidsstandardsprotocolsandprocedures
AT cardinalidanielpedro measurementofmelatonininbodyfluidsstandardsprotocolsandprocedures
AT browngregorym measurementofmelatonininbodyfluidsstandardsprotocolsandprocedures
AT pandiperumalseithikurippur measurementofmelatonininbodyfluidsstandardsprotocolsandprocedures
bdutipo_str Repositorios
_version_ 1764820525711884288

Ejemplares similares