Melatonin and human cardiovascular disease

Abstract: The possible therapeutic role of melatonin in the pathophysiology of coronary artery disorder (CAD) is increasingly being recognized. In humans, exogenous melatonin has been shown to decrease nocturnal hypertension, improve systolic and diastolic blood pressure, reduce the pulsatility inde...

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Autores principales: Pandi Perumal, Seithikurippu R., BaHammam, Ahmed S., Ojike, Nwakile I., Akinseye, Oluwaseun, Kendzerska, Tetyana, Buttoo, Kenneth, Dhandapany, Perundurai S., Brown, Gregory M., Cardinali, Daniel Pedro
Formato: Artículo
Lenguaje:Inglés
Inglés
Publicado: SAGE Publications 2019
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/1467
Aporte de:
id I33-R139123456789-1467
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
Inglés
topic MEDICINA
MELATONINA
PRESION SANGUINEA
ENFERMEDADES CARDIOVASCULARES
HIPERTENSION
spellingShingle MEDICINA
MELATONINA
PRESION SANGUINEA
ENFERMEDADES CARDIOVASCULARES
HIPERTENSION
Pandi Perumal, Seithikurippu R.
BaHammam, Ahmed S.
Ojike, Nwakile I.
Akinseye, Oluwaseun
Kendzerska, Tetyana
Buttoo, Kenneth
Dhandapany, Perundurai S.
Brown, Gregory M.
Cardinali, Daniel Pedro
Melatonin and human cardiovascular disease
topic_facet MEDICINA
MELATONINA
PRESION SANGUINEA
ENFERMEDADES CARDIOVASCULARES
HIPERTENSION
description Abstract: The possible therapeutic role of melatonin in the pathophysiology of coronary artery disorder (CAD) is increasingly being recognized. In humans, exogenous melatonin has been shown to decrease nocturnal hypertension, improve systolic and diastolic blood pressure, reduce the pulsatility index in the internal carotid artery, decrease platelet aggregation and reduce serum catecholamine levels. Low circulating levels of melatonin are reported in individuals with CAD, arterial hypertension and congestive heart failure. This review assesses current literature on the cardiovascular effects of melatonin in humans. It can be concluded that melatonin deserves to be considered in clinical trials evaluating novel therapeutic interventions for cardiovascular disorders.
format Artículo
author Pandi Perumal, Seithikurippu R.
BaHammam, Ahmed S.
Ojike, Nwakile I.
Akinseye, Oluwaseun
Kendzerska, Tetyana
Buttoo, Kenneth
Dhandapany, Perundurai S.
Brown, Gregory M.
Cardinali, Daniel Pedro
author_facet Pandi Perumal, Seithikurippu R.
BaHammam, Ahmed S.
Ojike, Nwakile I.
Akinseye, Oluwaseun
Kendzerska, Tetyana
Buttoo, Kenneth
Dhandapany, Perundurai S.
Brown, Gregory M.
Cardinali, Daniel Pedro
author_sort Pandi Perumal, Seithikurippu R.
title Melatonin and human cardiovascular disease
title_short Melatonin and human cardiovascular disease
title_full Melatonin and human cardiovascular disease
title_fullStr Melatonin and human cardiovascular disease
title_full_unstemmed Melatonin and human cardiovascular disease
title_sort melatonin and human cardiovascular disease
publisher SAGE Publications
publishDate 2019
url https://repositorio.uca.edu.ar/handle/123456789/1467
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