Timing is everything : circadian rhythms and their role in the control of sleep

Abstract: Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endogenous circadian clock, melatonin is c...

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Detalles Bibliográficos
Autores principales: Cardinali, Daniel Pedro, Pandi Perumal, Seithikurippu R., Zaki, Nevin F. W., Karthikeyan, Ramanujam, Spence, David Warren, Reiter, R., Brown, Gregory M.
Otros Autores: 0000-0002-8686-7259
Formato: Artículo
Lenguaje:Inglés
Publicado: Elsevier 2022
Materias:
SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/13636
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139123456789-13636
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO
spellingShingle SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO
Cardinali, Daniel Pedro
Pandi Perumal, Seithikurippu R.
Zaki, Nevin F. W.
Karthikeyan, Ramanujam
Spence, David Warren
Reiter, R.
Brown, Gregory M.
Timing is everything : circadian rhythms and their role in the control of sleep
topic_facet SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO
description Abstract: Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endogenous circadian clock, melatonin is critical for sleep regulation. Light serves as a cue for sleep/wake control by activating retino-recipient cells in the SCN and subsequently suppressing melatonin. Clock genes are the molecular timekeepers that keep the 24 h cycle in place. Two main sleep and behavioural disorder diagnostic manuals have now officially recognised the importance of these processes for human health and well-being. The body's ability to respond to daily demands with the least amount of effort is maximised by carefully timing and integrating all components of sleep and waking. In the brain, the organization of timing is essential for optimal brain physiology.
author2 0000-0002-8686-7259
author_facet 0000-0002-8686-7259
Cardinali, Daniel Pedro
Pandi Perumal, Seithikurippu R.
Zaki, Nevin F. W.
Karthikeyan, Ramanujam
Spence, David Warren
Reiter, R.
Brown, Gregory M.
format Artículo
author Cardinali, Daniel Pedro
Pandi Perumal, Seithikurippu R.
Zaki, Nevin F. W.
Karthikeyan, Ramanujam
Spence, David Warren
Reiter, R.
Brown, Gregory M.
author_sort Cardinali, Daniel Pedro
title Timing is everything : circadian rhythms and their role in the control of sleep
title_short Timing is everything : circadian rhythms and their role in the control of sleep
title_full Timing is everything : circadian rhythms and their role in the control of sleep
title_fullStr Timing is everything : circadian rhythms and their role in the control of sleep
title_full_unstemmed Timing is everything : circadian rhythms and their role in the control of sleep
title_sort timing is everything : circadian rhythms and their role in the control of sleep
publisher Elsevier
publishDate 2022
url https://repositorio.uca.edu.ar/handle/123456789/13636
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