Neuroinflammation : an integrating overview of reactive-neuroimmune cell interactions in health and disease

Abstract: The concept of central nervous system (CNS) inflammation has evolved over the last decades. Neuroinflammation is the response of reactive CNS components to altered homeostasis, regardless of the cause to be endogenous or exogenous. Neurological diseases, whether traumatic, neoplastic, isch...

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Detalles Bibliográficos
Autores principales: Kölliker Frers, Rodolfo, Udovin, Lucas Daniel, Otero Losada, Matilde, Kobiec, Tamara, Palacios, Jorge, Razzitte, Gabriela, Capani, Francisco, Herrera, María Inés
Formato: Artículo
Lenguaje:Inglés
Publicado: Hindawi 2021
Materias:
NEUROINFLAMACION
INFLAMACION
SISTEMA NERVIOSO CENTRAL
HOMEOSTASIS
SISTEMA INMUNOLOGICO
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/12501
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139123456789-12501
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic NEUROINFLAMACION
INFLAMACION
SISTEMA NERVIOSO CENTRAL
HOMEOSTASIS
SISTEMA INMUNOLOGICO
spellingShingle NEUROINFLAMACION
INFLAMACION
SISTEMA NERVIOSO CENTRAL
HOMEOSTASIS
SISTEMA INMUNOLOGICO
Kölliker Frers, Rodolfo
Udovin, Lucas Daniel
Otero Losada, Matilde
Kobiec, Tamara
Palacios, Jorge
Razzitte, Gabriela
Capani, Francisco
Herrera, María Inés
Neuroinflammation : an integrating overview of reactive-neuroimmune cell interactions in health and disease
topic_facet NEUROINFLAMACION
INFLAMACION
SISTEMA NERVIOSO CENTRAL
HOMEOSTASIS
SISTEMA INMUNOLOGICO
description Abstract: The concept of central nervous system (CNS) inflammation has evolved over the last decades. Neuroinflammation is the response of reactive CNS components to altered homeostasis, regardless of the cause to be endogenous or exogenous. Neurological diseases, whether traumatic, neoplastic, ischemic, metabolic, toxic, infectious, autoimmune, developmental, or degenerative, involve direct and indirect immune-related neuroinflammation. Brain infiltrates of the innate and adaptive immune system cells appear in response to an infective or otherwise noxious agent and produce inflammatory mediators. Mediators of inflammation include local and recruited cells and signals. Processes derived from extrinsic and intrinsic CNS diseases also elicit the CNS inflammatory response. A deeper understanding of immune-related inflammation in health and disease is necessary to find potential therapeutic targets for preventing or reducing CNS damage. This review is aimed at discussing the innate and adaptive immune system functions and their roles in regulating brain cell responses in disease and homeostasis maintenance.
format Artículo
author Kölliker Frers, Rodolfo
Udovin, Lucas Daniel
Otero Losada, Matilde
Kobiec, Tamara
Palacios, Jorge
Razzitte, Gabriela
Capani, Francisco
Herrera, María Inés
author_facet Kölliker Frers, Rodolfo
Udovin, Lucas Daniel
Otero Losada, Matilde
Kobiec, Tamara
Palacios, Jorge
Razzitte, Gabriela
Capani, Francisco
Herrera, María Inés
author_sort Kölliker Frers, Rodolfo
title Neuroinflammation : an integrating overview of reactive-neuroimmune cell interactions in health and disease
title_short Neuroinflammation : an integrating overview of reactive-neuroimmune cell interactions in health and disease
title_full Neuroinflammation : an integrating overview of reactive-neuroimmune cell interactions in health and disease
title_fullStr Neuroinflammation : an integrating overview of reactive-neuroimmune cell interactions in health and disease
title_full_unstemmed Neuroinflammation : an integrating overview of reactive-neuroimmune cell interactions in health and disease
title_sort neuroinflammation : an integrating overview of reactive-neuroimmune cell interactions in health and disease
publisher Hindawi
publishDate 2021
url https://repositorio.uca.edu.ar/handle/123456789/12501
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AT udovinlucasdaniel neuroinflammationanintegratingoverviewofreactiveneuroimmunecellinteractionsinhealthanddisease
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bdutipo_str Repositorios
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