Neuroprotective properties of cannabinoids in cellular and animal models : hypotheses and facts

Abstract: Progressive neuronal loss is a typical characteristic of neurodegenerative diseases. In Parkinson’s disease, the loss of dopaminergic neurons in the basal ganglia results in impaired mobility and flawed muscle control. The loss of cholinergic neurons largely in the basal forebrain contr...

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Autores principales: Udovin, Lucas Daniel, Aguilar, Andrea, Kobiec, Tamara, Herrera, María Inés, Pérez Lloret, Santiago, Toro-Urrego, Nicolás, Kölliker Frers, Rodolfo
Formato: Parte de libro
Lenguaje:Inglés
Publicado: Matilde Otero-Losada. Universidad de Buenos Aires 2021
Materias:
ENFERMEDADES NEURODEGENERATIVAS
ENFERMEDAD DE PARKINSON
NEURODEGENERACION
NEUROPROTECCION
DAÑO CEREBRAL
MUERTE CELULAR
LIPIDOS
PALMITOILETANOLAMIDA
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/11313
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139123456789-11313
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic ENFERMEDADES NEURODEGENERATIVAS
ENFERMEDAD DE PARKINSON
NEURODEGENERACION
NEUROPROTECCION
DAÑO CEREBRAL
MUERTE CELULAR
LIPIDOS
PALMITOILETANOLAMIDA
spellingShingle ENFERMEDADES NEURODEGENERATIVAS
ENFERMEDAD DE PARKINSON
NEURODEGENERACION
NEUROPROTECCION
DAÑO CEREBRAL
MUERTE CELULAR
LIPIDOS
PALMITOILETANOLAMIDA
Udovin, Lucas Daniel
Aguilar, Andrea
Kobiec, Tamara
Herrera, María Inés
Pérez Lloret, Santiago
Toro-Urrego, Nicolás
Kölliker Frers, Rodolfo
Neuroprotective properties of cannabinoids in cellular and animal models : hypotheses and facts
topic_facet ENFERMEDADES NEURODEGENERATIVAS
ENFERMEDAD DE PARKINSON
NEURODEGENERACION
NEUROPROTECCION
DAÑO CEREBRAL
MUERTE CELULAR
LIPIDOS
PALMITOILETANOLAMIDA
description Abstract: Progressive neuronal loss is a typical characteristic of neurodegenerative diseases. In Parkinson’s disease, the loss of dopaminergic neurons in the basal ganglia results in impaired mobility and flawed muscle control. The loss of cholinergic neurons largely in the basal forebrain contributes to memory and attention deficits and the overall cognitive impairment in Alzheimer’s disease. This being said, neuroprotective drugs should be expected to preserve and/or restore the functions affected by neuronal loss, and substantially prevent cell death. The endocannabinoid system, comprising lipid mediators able to bind to and activate cannabinoid receptors, has emerged as a therapeutic target of potential interest in a variety of central nervous system diseases.
format Parte de libro
author Udovin, Lucas Daniel
Aguilar, Andrea
Kobiec, Tamara
Herrera, María Inés
Pérez Lloret, Santiago
Toro-Urrego, Nicolás
Kölliker Frers, Rodolfo
author_facet Udovin, Lucas Daniel
Aguilar, Andrea
Kobiec, Tamara
Herrera, María Inés
Pérez Lloret, Santiago
Toro-Urrego, Nicolás
Kölliker Frers, Rodolfo
author_sort Udovin, Lucas Daniel
title Neuroprotective properties of cannabinoids in cellular and animal models : hypotheses and facts
title_short Neuroprotective properties of cannabinoids in cellular and animal models : hypotheses and facts
title_full Neuroprotective properties of cannabinoids in cellular and animal models : hypotheses and facts
title_fullStr Neuroprotective properties of cannabinoids in cellular and animal models : hypotheses and facts
title_full_unstemmed Neuroprotective properties of cannabinoids in cellular and animal models : hypotheses and facts
title_sort neuroprotective properties of cannabinoids in cellular and animal models : hypotheses and facts
publisher Matilde Otero-Losada. Universidad de Buenos Aires
publishDate 2021
url https://repositorio.uca.edu.ar/handle/123456789/11313
work_keys_str_mv AT udovinlucasdaniel neuroprotectivepropertiesofcannabinoidsincellularandanimalmodelshypothesesandfacts
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bdutipo_str Repositorios
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