Development and validation of the dystonia-pain classification System : a multicenter study
Abstract: Background: Dystonia is associated with disabling nonmotor symptoms like chronic pain (CP), which is prevalent in dystonia and significantly impacts the quality of life (QoL). There is no validated tool for assessing CP in dystonia, which substantially hampers pain management. Objecti...
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| Formato: | Artículo |
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Wiley
2023
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| Acceso en línea: | https://repositorio.uca.edu.ar/handle/123456789/17343 |
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I33-R139-123456789-173432023-11-23T18:02:13Z Development and validation of the dystonia-pain classification System : a multicenter study Listik, Clarice Listik, Eduardo Santos Rolim, Flavia de Paiva Cury Portela, Denise Maria Meneses Pérez Lloret, Santiago Araújo, Natalia Rebeca de Alves Carvalho, Pedro Rubens Araújo Santos, Graziele Costa Limongi, João Carlos Papaterra Cardoso, Francisco Mylius, Veit Brugger, Florian Mercia Fernandes, Ana Barbosa, Egberto R. Teixeira, Manoel J. Ferraz, Henrique Ballalai Camargos, Sarah Teixeira Gisbert Cury, Rubens Ciampi de Andrade, Daniel DOLOR DISTONÍA TRASTORNOS DEL MOVIMIENTO SINTOMAS NO MOTORES Abstract: Background: Dystonia is associated with disabling nonmotor symptoms like chronic pain (CP), which is prevalent in dystonia and significantly impacts the quality of life (QoL). There is no validated tool for assessing CP in dystonia, which substantially hampers pain management. Objective: The aim was to develop a CP classification and scoring system for dystonia. Methods: A multidisciplinary group was established to develop the Dystonia-Pain Classification System (Dystonia- PCS). The classification of CP as related or unrelated to dystonia was followed by the assessment of pain severity score, encompassing pain intensity, frequency, and impact on daily living. Then, consecutive patients with inherited/idiopathic dystonia of different spatial distribution were recruited in a cross-sectional multicenter validation study. Dystonia-PCS was compared to validated pain, mood, QoL, and dystonia scales (Brief Pain Inventory, Douleur Neuropathique-4 questionnaire, European QoL-5 Dimensions-3 Level Version, and Burke–Fahn–Marsden Dystonia Rating Scale). Results: CP was present in 81 of 123 recruited patients, being directly related to dystonia in 82.7%, aggravated by dystonia in 8.8%, and nonrelated to dystonia in 7.5%. affected by this disorder. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. Dystonia-PCS had excellent intra-rater (Intraclass Correlation Coefficient - ICC: 0.941) and inter-rater (ICC: 0.867) reliability. In addition, pain severity score correlated with European QoL-5 Dimensions-3 Level Version’s pain subscore (r = 0.635, P < 0.001) and the Brief Pain Inventory’s severity and interference scores (r = 0.553, P < 0.001 and r = 0.609, P < 0.001, respectively). Conclusions: Dystonia-PCS is a reliable tool to categorize and quantify CP impact in dystonia and will help improve clinical trial design and management of CP in patients affected by this disorder. 2023-10-24T08:31:27Z 2023-10-24T08:31:27Z 2023 Artículo Listik, C., Listik, E., Santos Rolim, F. de Paiva, et al. Development and validation of the dystonia-pain classification System : a multicenter study [en línea]. Movement Disorders. 2023, 38(7). doi: 10.1002/mds.29423 . Disponible en: https://repositorio.uca.edu.ar/handle/123456789/17343 1531-8257 (online) 0885-3185 (impreso) https://repositorio.uca.edu.ar/handle/123456789/17343 10.1002/mds.29423 37208983 eng Acceso abierto http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Wiley Movement Disorders. 2023, 38(7) |
| institution |
Universidad Católica Argentina |
| institution_str |
I-33 |
| repository_str |
R-139 |
| collection |
Repositorio Institucional de la Universidad Católica Argentina (UCA) |
| language |
Inglés |
| topic |
DOLOR DISTONÍA TRASTORNOS DEL MOVIMIENTO SINTOMAS NO MOTORES |
| spellingShingle |
DOLOR DISTONÍA TRASTORNOS DEL MOVIMIENTO SINTOMAS NO MOTORES Listik, Clarice Listik, Eduardo Santos Rolim, Flavia de Paiva Cury Portela, Denise Maria Meneses Pérez Lloret, Santiago Araújo, Natalia Rebeca de Alves Carvalho, Pedro Rubens Araújo Santos, Graziele Costa Limongi, João Carlos Papaterra Cardoso, Francisco Mylius, Veit Brugger, Florian Mercia Fernandes, Ana Barbosa, Egberto R. Teixeira, Manoel J. Ferraz, Henrique Ballalai Camargos, Sarah Teixeira Gisbert Cury, Rubens Ciampi de Andrade, Daniel Development and validation of the dystonia-pain classification System : a multicenter study |
| topic_facet |
DOLOR DISTONÍA TRASTORNOS DEL MOVIMIENTO SINTOMAS NO MOTORES |
| description |
Abstract: Background: Dystonia is associated with
disabling nonmotor symptoms like chronic pain (CP), which
is prevalent in dystonia and significantly impacts the quality
of life (QoL). There is no validated tool for assessing CP in
dystonia, which substantially hampers pain management.
Objective: The aim was to develop a CP classification
and scoring system for dystonia.
Methods: A multidisciplinary group was established to
develop the Dystonia-Pain Classification System (Dystonia-
PCS). The classification of CP as related or unrelated to dystonia
was followed by the assessment of pain severity score,
encompassing pain intensity, frequency, and impact on daily
living. Then, consecutive patients with inherited/idiopathic
dystonia of different spatial distribution were recruited in a
cross-sectional multicenter validation study. Dystonia-PCS
was compared to validated pain, mood, QoL, and dystonia
scales (Brief Pain Inventory, Douleur Neuropathique-4 questionnaire,
European QoL-5 Dimensions-3 Level Version, and
Burke–Fahn–Marsden Dystonia Rating Scale).
Results: CP was present in 81 of 123 recruited patients,
being directly related to dystonia in 82.7%, aggravated
by dystonia in 8.8%, and nonrelated to dystonia in 7.5%. affected by this disorder. © 2023 The Authors. Movement
Disorders published by Wiley Periodicals LLC on behalf of
International Parkinson and Movement Disorder Society.
Dystonia-PCS had excellent intra-rater (Intraclass Correlation
Coefficient - ICC: 0.941) and inter-rater (ICC:
0.867) reliability. In addition, pain severity score correlated
with European QoL-5 Dimensions-3 Level Version’s
pain subscore (r = 0.635, P < 0.001) and the Brief Pain
Inventory’s severity and interference scores (r = 0.553,
P < 0.001 and r = 0.609, P < 0.001, respectively).
Conclusions: Dystonia-PCS is a reliable tool to categorize
and quantify CP impact in dystonia and will help improve
clinical trial design and management of CP in patients affected by this disorder. |
| format |
Artículo |
| author |
Listik, Clarice Listik, Eduardo Santos Rolim, Flavia de Paiva Cury Portela, Denise Maria Meneses Pérez Lloret, Santiago Araújo, Natalia Rebeca de Alves Carvalho, Pedro Rubens Araújo Santos, Graziele Costa Limongi, João Carlos Papaterra Cardoso, Francisco Mylius, Veit Brugger, Florian Mercia Fernandes, Ana Barbosa, Egberto R. Teixeira, Manoel J. Ferraz, Henrique Ballalai Camargos, Sarah Teixeira Gisbert Cury, Rubens Ciampi de Andrade, Daniel |
| author_facet |
Listik, Clarice Listik, Eduardo Santos Rolim, Flavia de Paiva Cury Portela, Denise Maria Meneses Pérez Lloret, Santiago Araújo, Natalia Rebeca de Alves Carvalho, Pedro Rubens Araújo Santos, Graziele Costa Limongi, João Carlos Papaterra Cardoso, Francisco Mylius, Veit Brugger, Florian Mercia Fernandes, Ana Barbosa, Egberto R. Teixeira, Manoel J. Ferraz, Henrique Ballalai Camargos, Sarah Teixeira Gisbert Cury, Rubens Ciampi de Andrade, Daniel |
| author_sort |
Listik, Clarice |
| title |
Development and validation of the dystonia-pain classification System : a multicenter study |
| title_short |
Development and validation of the dystonia-pain classification System : a multicenter study |
| title_full |
Development and validation of the dystonia-pain classification System : a multicenter study |
| title_fullStr |
Development and validation of the dystonia-pain classification System : a multicenter study |
| title_full_unstemmed |
Development and validation of the dystonia-pain classification System : a multicenter study |
| title_sort |
development and validation of the dystonia-pain classification system : a multicenter study |
| publisher |
Wiley |
| publishDate |
2023 |
| url |
https://repositorio.uca.edu.ar/handle/123456789/17343 |
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