On the diagnosis of pain in Parkinson disease : a mechanism-based approach

Abstract: We read with interest the article entitled “Pain in the neurodegenerating brain: insights into pharmacotherapy for Alzheimer disease and Parkinson disease” from Timothy Lawn et al. Their review summarized the current findings on pain processing as well as on pharmacotherapy of pain in...

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Detalles Bibliográficos
Autores principales: Mylius, Veit, Pérez Lloret, Santiago, Ciampi de Andrade, Daniel
Formato: Artículo
Lenguaje:Inglés
Publicado: Lippinkott 2023
Materias:
ENFERMEDAD DE PARKINSON
ENFERMEDADES NEURODEGENERATIVAS
DOLOR
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/16227
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139-123456789-16227
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic ENFERMEDAD DE PARKINSON
ENFERMEDADES NEURODEGENERATIVAS
DOLOR
spellingShingle ENFERMEDAD DE PARKINSON
ENFERMEDADES NEURODEGENERATIVAS
DOLOR
Mylius, Veit
Pérez Lloret, Santiago
Ciampi de Andrade, Daniel
On the diagnosis of pain in Parkinson disease : a mechanism-based approach
topic_facet ENFERMEDAD DE PARKINSON
ENFERMEDADES NEURODEGENERATIVAS
DOLOR
description Abstract: We read with interest the article entitled “Pain in the neurodegenerating brain: insights into pharmacotherapy for Alzheimer disease and Parkinson disease” from Timothy Lawn et al. Their review summarized the current findings on pain processing as well as on pharmacotherapy of pain in both diseases. It further emphasizes the importance of mechanistic research for evidence-based pain medicine. We would like to comment on the experimental findings and on the importance of a mechanism-based approach in Parkinson disease (PD) after the correct diagnosis of PDrelated pain has been made because a mechanism-based approach has been already validated. Concerning experimental pain sensitivity, studies revealed increased pain sensitivity when tested in the medication defined off phase, whereas converse observations were made in the on phase. Increased pain sensitivity can be reversed by L-dopa or deep brain stimulation.
format Artículo
author Mylius, Veit
Pérez Lloret, Santiago
Ciampi de Andrade, Daniel
author_facet Mylius, Veit
Pérez Lloret, Santiago
Ciampi de Andrade, Daniel
author_sort Mylius, Veit
title On the diagnosis of pain in Parkinson disease : a mechanism-based approach
title_short On the diagnosis of pain in Parkinson disease : a mechanism-based approach
title_full On the diagnosis of pain in Parkinson disease : a mechanism-based approach
title_fullStr On the diagnosis of pain in Parkinson disease : a mechanism-based approach
title_full_unstemmed On the diagnosis of pain in Parkinson disease : a mechanism-based approach
title_sort on the diagnosis of pain in parkinson disease : a mechanism-based approach
publisher Lippinkott
publishDate 2023
url https://repositorio.uca.edu.ar/handle/123456789/16227
work_keys_str_mv AT myliusveit onthediagnosisofpaininparkinsondiseaseamechanismbasedapproach
AT perezlloretsantiago onthediagnosisofpaininparkinsondiseaseamechanismbasedapproach
AT ciampideandradedaniel onthediagnosisofpaininparkinsondiseaseamechanismbasedapproach
bdutipo_str Repositorios
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