Recent applications of superresolution microscopy in neurobiology

Abstract: Chemical synapses in brain are structural differentiations where excitatory or inhibitory signals are vectorially transmitted between two neurons. Excitatory synapses occur mostly on dendritic spines, submicron sized protrusions of the neuronal dendritic arborizations. Axons establish cont...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Willig, Katrin I., Barrantes, Francisco José
Formato: Artículo
Lenguaje:Inglés
Publicado: Elsevier 2022
Materias:
CEREBRO
NEUROBIOLOGIA
PROTEINAS
SINAPSIS
MICROSCOPIA
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/15338
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139-123456789-15338
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic CEREBRO
NEUROBIOLOGIA
PROTEINAS
SINAPSIS
MICROSCOPIA
spellingShingle CEREBRO
NEUROBIOLOGIA
PROTEINAS
SINAPSIS
MICROSCOPIA
Willig, Katrin I.
Barrantes, Francisco José
Recent applications of superresolution microscopy in neurobiology
topic_facet CEREBRO
NEUROBIOLOGIA
PROTEINAS
SINAPSIS
MICROSCOPIA
description Abstract: Chemical synapses in brain are structural differentiations where excitatory or inhibitory signals are vectorially transmitted between two neurons. Excitatory synapses occur mostly on dendritic spines, submicron sized protrusions of the neuronal dendritic arborizations. Axons establish contacts with these tiny specializations purported to be the smallest functional processing units in the central nervous system. The minute size of synapses and their macromolecular constituents creates an inherent difficulty for imaging but makes them an ideal object for superresolution microscopy. Here we discuss some representative examples of nanoscopy studies, ranging from quantification of receptors and scaffolding proteins in postsynaptic densities and their dynamic behavior, to imaging of synaptic vesicle proteins and dendritic spines in living neurons or even live animals.
format Artículo
author Willig, Katrin I.
Barrantes, Francisco José
author_facet Willig, Katrin I.
Barrantes, Francisco José
author_sort Willig, Katrin I.
title Recent applications of superresolution microscopy in neurobiology
title_short Recent applications of superresolution microscopy in neurobiology
title_full Recent applications of superresolution microscopy in neurobiology
title_fullStr Recent applications of superresolution microscopy in neurobiology
title_full_unstemmed Recent applications of superresolution microscopy in neurobiology
title_sort recent applications of superresolution microscopy in neurobiology
publisher Elsevier
publishDate 2022
url https://repositorio.uca.edu.ar/handle/123456789/15338
work_keys_str_mv AT willigkatrini recentapplicationsofsuperresolutionmicroscopyinneurobiology
AT barrantesfranciscojose recentapplicationsofsuperresolutionmicroscopyinneurobiology
bdutipo_str Repositorios
_version_ 1764820523679744002

Ejemplares similares