Mitochondrial lineage A2ah found in a pre-Hispanic individual from the Andean region

Abstract: Abstract Objectives: The aim of this study was to contribute to the knowledge of preHispanic Andean mitochondrial diversity by analyzing an individual from the archaeological site Pukara de La Cueva (North-western Argentina). The date of the discovery context (540 6 60 BP) corresponds t...

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Autores principales: Russo, M G, Dejean, C. B., Avena, S. A., Seldes, V., Ramundo, Paola Silvia
Formato: Artículo
Lenguaje:Inglés
Publicado: Wiley 2022
Materias:
CULTURAS PRECOLOMBINAS
ADN
GENETICA
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/14743
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139-123456789-14743
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic CULTURAS PRECOLOMBINAS
ADN
GENETICA
spellingShingle CULTURAS PRECOLOMBINAS
ADN
GENETICA
Russo, M G
Dejean, C. B.
Avena, S. A.
Seldes, V.
Ramundo, Paola Silvia
Mitochondrial lineage A2ah found in a pre-Hispanic individual from the Andean region
topic_facet CULTURAS PRECOLOMBINAS
ADN
GENETICA
description Abstract: Abstract Objectives: The aim of this study was to contribute to the knowledge of preHispanic Andean mitochondrial diversity by analyzing an individual from the archaeological site Pukara de La Cueva (North-western Argentina). The date of the discovery context (540 6 60 BP) corresponds to the Regional Developments II period. Methods: Two separate DNA extractions were performed from dentin powder of one tooth. HVR I was amplified by PCR from each extract in three overlapping fragments and the haplotype was determined by consensus among all obtained sequences. The procedures were carried out under strict protocols developed for working with ancient DNA. Results: The individual belonged to the A2ah lineage due to the presence of the 16097C and 16098G transitions, which constitute its distinctive motif. This lineage is very rare in Native American populations and was described in four individuals from current groups inhabiting the Bolivian Llanos, two from South-eastern Brazil, and one from the Gran Chaco region. In addition, two other mutations (16260T and 16286T) were shared with one of the individuals from the Bolivian Llanos region. Conclusions: Considering that the origin of this lineage was postulated for the South American lowlands, the present pre-Hispanic discovery in the Andean area could be taken as a new evidence of gene flow between these regions. Also, it allows the questioning of the geographical origin of this mitochondrial lineage.
format Artículo
author Russo, M G
Dejean, C. B.
Avena, S. A.
Seldes, V.
Ramundo, Paola Silvia
author_facet Russo, M G
Dejean, C. B.
Avena, S. A.
Seldes, V.
Ramundo, Paola Silvia
author_sort Russo, M G
title Mitochondrial lineage A2ah found in a pre-Hispanic individual from the Andean region
title_short Mitochondrial lineage A2ah found in a pre-Hispanic individual from the Andean region
title_full Mitochondrial lineage A2ah found in a pre-Hispanic individual from the Andean region
title_fullStr Mitochondrial lineage A2ah found in a pre-Hispanic individual from the Andean region
title_full_unstemmed Mitochondrial lineage A2ah found in a pre-Hispanic individual from the Andean region
title_sort mitochondrial lineage a2ah found in a pre-hispanic individual from the andean region
publisher Wiley
publishDate 2022
url https://repositorio.uca.edu.ar/handle/123456789/14743
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AT avenasa mitochondriallineagea2ahfoundinaprehispanicindividualfromtheandeanregion
AT seldesv mitochondriallineagea2ahfoundinaprehispanicindividualfromtheandeanregion
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bdutipo_str Repositorios
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