Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
Abstract: Brain injury constitutes a disabling health condition of several etiologies. One of the major causes of brain injury is hypoxia-ischemia. Until recently, pharmacological treatments were solely focused on neurons. In the last decades, glial cells started to be considered as alternative ta...
Guardado en:
| Autores principales: | , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Bentham Science Publishers
2022
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| Materias: | |
| Acceso en línea: | https://repositorio.uca.edu.ar/handle/123456789/14724 |
| Aporte de: |
| Sumario: | Abstract: Brain injury constitutes a disabling health condition of several etiologies. One of the major causes of
brain injury is hypoxia-ischemia. Until recently, pharmacological treatments were solely focused on neurons. In
the last decades, glial cells started to be considered as alternative targets for neuroprotection. Novel treatments for hypoxia-ischemia intend to modulate reactive forms of glial cells, and/or potentiate their recovery response. In this review, we summarize these neuroprotective strategies in hypoxia-ischemia and discuss their mechanisms of action. |
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