Neuroprotection in hypoxic-ischemic brain injury targeting glial cells

Abstract: Brain injury constitutes a disabling health condition of several etiologies. One of the major causes of brain injury is hypoxia-ischemia. Until recently, pharmacological treatments were solely focused on neurons. In the last decades, glial cells started to be considered as alternative ta...

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Autores principales: Herrera, María Inés, Mucci, Sofía, Barreto, George E., Kölliker Frers, Rodolfo, Capani, Francisco
Formato: Artículo
Lenguaje:Inglés
Publicado: Bentham Science Publishers 2022
Materias:
NEUROPROTECCION
HIPOXIA
TRATAMIENTO FARMACOLOGICO
CELULAS GLIALES
DAÑO CEREBRAL
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/14724
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139-123456789-14724
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic NEUROPROTECCION
HIPOXIA
TRATAMIENTO FARMACOLOGICO
CELULAS GLIALES
DAÑO CEREBRAL
spellingShingle NEUROPROTECCION
HIPOXIA
TRATAMIENTO FARMACOLOGICO
CELULAS GLIALES
DAÑO CEREBRAL
Herrera, María Inés
Mucci, Sofía
Barreto, George E.
Kölliker Frers, Rodolfo
Capani, Francisco
Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
topic_facet NEUROPROTECCION
HIPOXIA
TRATAMIENTO FARMACOLOGICO
CELULAS GLIALES
DAÑO CEREBRAL
description Abstract: Brain injury constitutes a disabling health condition of several etiologies. One of the major causes of brain injury is hypoxia-ischemia. Until recently, pharmacological treatments were solely focused on neurons. In the last decades, glial cells started to be considered as alternative targets for neuroprotection. Novel treatments for hypoxia-ischemia intend to modulate reactive forms of glial cells, and/or potentiate their recovery response. In this review, we summarize these neuroprotective strategies in hypoxia-ischemia and discuss their mechanisms of action.
format Artículo
author Herrera, María Inés
Mucci, Sofía
Barreto, George E.
Kölliker Frers, Rodolfo
Capani, Francisco
author_facet Herrera, María Inés
Mucci, Sofía
Barreto, George E.
Kölliker Frers, Rodolfo
Capani, Francisco
author_sort Herrera, María Inés
title Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
title_short Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
title_full Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
title_fullStr Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
title_full_unstemmed Neuroprotection in hypoxic-ischemic brain injury targeting glial cells
title_sort neuroprotection in hypoxic-ischemic brain injury targeting glial cells
publisher Bentham Science Publishers
publishDate 2022
url https://repositorio.uca.edu.ar/handle/123456789/14724
work_keys_str_mv AT herreramariaines neuroprotectioninhypoxicischemicbraininjurytargetingglialcells
AT muccisofia neuroprotectioninhypoxicischemicbraininjurytargetingglialcells
AT barretogeorgee neuroprotectioninhypoxicischemicbraininjurytargetingglialcells
AT kollikerfrersrodolfo neuroprotectioninhypoxicischemicbraininjurytargetingglialcells
AT capanifrancisco neuroprotectioninhypoxicischemicbraininjurytargetingglialcells
bdutipo_str Repositorios
_version_ 1764820523722735622

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