Management of constipation in Parkinson’s disease

Abstract Introduction: Constipation is a frequent non-motor feature of Parkinson’s disease (PD). It is the most common gastrointestinal symptom of the disease and it can precede motor symptoms by as much as 20 years. Constipation can produce discomfort and affect activities of daily living, produ...

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Autores principales: Rossi, Marcelo, Merello, Marcelo, Pérez Lloret, Santiago
Formato: Artículo
Lenguaje:Inglés
Publicado: Taylor & Francis 2022
Materias:
CONSTIPACION
TRANSTORNOS DIGESTIVOS
ENFERMEDAD DE PARKINSON
LAXANTES
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/14250
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139-123456789-14250
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic CONSTIPACION
TRANSTORNOS DIGESTIVOS
ENFERMEDAD DE PARKINSON
LAXANTES
spellingShingle CONSTIPACION
TRANSTORNOS DIGESTIVOS
ENFERMEDAD DE PARKINSON
LAXANTES
Rossi, Marcelo
Merello, Marcelo
Pérez Lloret, Santiago
Management of constipation in Parkinson’s disease
topic_facet CONSTIPACION
TRANSTORNOS DIGESTIVOS
ENFERMEDAD DE PARKINSON
LAXANTES
description Abstract Introduction: Constipation is a frequent non-motor feature of Parkinson’s disease (PD). It is the most common gastrointestinal symptom of the disease and it can precede motor symptoms by as much as 20 years. Constipation can produce discomfort and affect activities of daily living, productivity and quality of life, thus warranting early diagnosis and treatment. Areas covered: In this review, the safety and efficacy of traditional and novel strategies for constipation management will be discussed. A treatment algorithm for constipation in PD will be presented. Expert opinion: Polyethylene glycol and lubiprostone are first-line compounds recommended by evidence-based medicine guidelines for the treatment of constipation due to slow colonic transit in PD. Management of constipation secondary to defecatory dysfunction due to pelvic floor dyssynergia can be done by levodopa or apomorphine injections, botulinum toxin type A injection into the puborectalis muscle, and nonpharmacological interventions, like biofeedback therapy or functional magnetic stimulation, which showed some benefit in PD patients with constipation, but in general more extensive studies are warranted.
format Artículo
author Rossi, Marcelo
Merello, Marcelo
Pérez Lloret, Santiago
author_facet Rossi, Marcelo
Merello, Marcelo
Pérez Lloret, Santiago
author_sort Rossi, Marcelo
title Management of constipation in Parkinson’s disease
title_short Management of constipation in Parkinson’s disease
title_full Management of constipation in Parkinson’s disease
title_fullStr Management of constipation in Parkinson’s disease
title_full_unstemmed Management of constipation in Parkinson’s disease
title_sort management of constipation in parkinson’s disease
publisher Taylor & Francis
publishDate 2022
url https://repositorio.uca.edu.ar/handle/123456789/14250
work_keys_str_mv AT rossimarcelo managementofconstipationinparkinsonsdisease
AT merellomarcelo managementofconstipationinparkinsonsdisease
AT perezlloretsantiago managementofconstipationinparkinsonsdisease
bdutipo_str Repositorios
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