Oculomotor abnormalities during reading in the offspring of late-onset alzheimer’s disease

Abstract: Introduction: Eye movement patterns during reading are well defined and documented. Each eye movement ends up in a fixation point, which allows the brain to process the incoming information and program the following saccade. In this work, we investigated whether eye movement alterations...

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Autores principales: Fernández, Gerardo, González, Ana Paula, Abulafia, Carolina Andrea, Fiorentini, Leticia, Agamennoni, Osvaldo, Guinjoan, Salvador M.
Formato: Artículo
Lenguaje:Inglés
Publicado: Bentham Science Publishers 2022
Materias:
ENFERMEDAD DE ALZHEIMER
HIJOS
DETERIORO COGNITIVO
OJOS
LECTURA
DETERIORO OCULOMOTOR
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/14021
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina
id I33-R139-123456789-14021
record_format dspace
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic ENFERMEDAD DE ALZHEIMER
HIJOS
DETERIORO COGNITIVO
OJOS
LECTURA
DETERIORO OCULOMOTOR
spellingShingle ENFERMEDAD DE ALZHEIMER
HIJOS
DETERIORO COGNITIVO
OJOS
LECTURA
DETERIORO OCULOMOTOR
Fernández, Gerardo
González, Ana Paula
Abulafia, Carolina Andrea
Fiorentini, Leticia
Agamennoni, Osvaldo
Guinjoan, Salvador M.
Oculomotor abnormalities during reading in the offspring of late-onset alzheimer’s disease
topic_facet ENFERMEDAD DE ALZHEIMER
HIJOS
DETERIORO COGNITIVO
OJOS
LECTURA
DETERIORO OCULOMOTOR
description Abstract: Introduction: Eye movement patterns during reading are well defined and documented. Each eye movement ends up in a fixation point, which allows the brain to process the incoming information and program the following saccade. In this work, we investigated whether eye movement alterations during a reading task might be already present in middle-aged, cognitively normal offspring of late-onset Alzheimer’s disease (O-LOAD). Methods: 18 O-LOAD and 18 age-matched healthy individuals with no family history of LOAD participated in the study. Participants were seated in front of a 20-inch LCD monitor, and single sentences were presented on it. Eye movements were recorded with an eye tracker with a sampling rate of 1000 Hz. Results: Analysis of eye movements during reading revealed that O-LOAD displayed more fixations, shorter saccades, and shorter fixation durations than controls. Conclusion: The present study shows that O-LOAD experienced alterations in their eye movements during reading. O-LOAD eye movement behavior could be considered an initial sign of oculomotor impairment. Hence, the evaluation of eye movement during reading might be a useful tool for monitoring well-defined cognitive resources.
format Artículo
author Fernández, Gerardo
González, Ana Paula
Abulafia, Carolina Andrea
Fiorentini, Leticia
Agamennoni, Osvaldo
Guinjoan, Salvador M.
author_facet Fernández, Gerardo
González, Ana Paula
Abulafia, Carolina Andrea
Fiorentini, Leticia
Agamennoni, Osvaldo
Guinjoan, Salvador M.
author_sort Fernández, Gerardo
title Oculomotor abnormalities during reading in the offspring of late-onset alzheimer’s disease
title_short Oculomotor abnormalities during reading in the offspring of late-onset alzheimer’s disease
title_full Oculomotor abnormalities during reading in the offspring of late-onset alzheimer’s disease
title_fullStr Oculomotor abnormalities during reading in the offspring of late-onset alzheimer’s disease
title_full_unstemmed Oculomotor abnormalities during reading in the offspring of late-onset alzheimer’s disease
title_sort oculomotor abnormalities during reading in the offspring of late-onset alzheimer’s disease
publisher Bentham Science Publishers
publishDate 2022
url https://repositorio.uca.edu.ar/handle/123456789/14021
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