A new take on optimal vaccine prioritization: when age-based strategy is efficient?

"The rapid spread, high mortality rate, and hospital overcrowding made the SARS-CoV-2 virus a significant challenge for humanity. The emergent situation urgently called for investments in vaccine development as a critical measure to mitigate this issue. However, the financial costs and time req...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chaves Rêgo, Leandro, Fierens, Pablo Ignacio, Gonçalves, Miguel
Formato: Artículo de publicación periódica
Lenguaje:en_US
Publicado: Springer Nature 2026
Materias:
AGING POPULATION, LIVE ATTENUATED VACCINES, GENE TARGETING, IMMUNIZATION, INACTIVATED VACCINES, VACCINES
ENVEJECIMIENTO POBLACIONAL, VACUNAS VIVAS ATENUADAS, DIRECCIONAMIENTO DE GENES, TARGETING GENÉTICO, INMUNIZACIÓN, VACUNAS ACTIVADAS, VACUNAS
Acceso en línea:https://hdl.handle.net/20.500.14769/5266
https://doi.org/10.1007/s41060-026-01053-5
Aporte de:
Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA) de Instituto Tecnológico de Buenos Aires (ITBA)
id I32-R138-20.500.14769-5266
record_format dspace
spelling I32-R138-20.500.14769-52662026-03-13T08:52:35Z A new take on optimal vaccine prioritization: when age-based strategy is efficient? Chaves Rêgo, Leandro Fierens, Pablo Ignacio Gonçalves, Miguel AGING POPULATION, LIVE ATTENUATED VACCINES, GENE TARGETING, IMMUNIZATION, INACTIVATED VACCINES, VACCINES ENVEJECIMIENTO POBLACIONAL, VACUNAS VIVAS ATENUADAS, DIRECCIONAMIENTO DE GENES, TARGETING GENÉTICO, INMUNIZACIÓN, VACUNAS ACTIVADAS, VACUNAS "The rapid spread, high mortality rate, and hospital overcrowding made the SARS-CoV-2 virus a significant challenge for humanity. The emergent situation urgently called for investments in vaccine development as a critical measure to mitigate this issue. However, the financial costs and time required for vaccine development posed considerable obstacles to achieving comprehensive vaccination coverage. Therefore, understanding the most effective immunization strategy was paramount to contain the virus’s spread and optimize resource allocation in public policies. Age-based prioritization was applied in many regions, and one of the objectives of this work is to study under which circumstances such a strategy is efficient. Our results show that age-based vaccination is a poor strategy for disease eradication, although it has a fair performance in diminishing the number of deaths. Furthermore, other schemes, such as PageRank-based immunization, are much better options in general. We believe these results are of relevance, not only for the past SARS-CoV-2 pandemic, but also for future epidemic outbreaks". 2026-03-12T13:11:27Z 2026-03-12T13:11:27Z 2026-03-12 Artículo de publicación periódica Gonçalves, M., Fierens, P.I. & Rêgo, L.C. A new take on optimal vaccine prioritization: when age-based strategy is efficient?. Int J Data Sci Anal 22, 95 (2026). https://doi.org/10.1007/s41060-026-01053-5 https://hdl.handle.net/20.500.14769/5266 https://doi.org/10.1007/s41060-026-01053-5 en_US application/pdf Springer Nature
institution Instituto Tecnológico de Buenos Aires (ITBA)
institution_str I-32
repository_str R-138
collection Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA)
language en_US
topic AGING POPULATION, LIVE ATTENUATED VACCINES, GENE TARGETING, IMMUNIZATION, INACTIVATED VACCINES, VACCINES
ENVEJECIMIENTO POBLACIONAL, VACUNAS VIVAS ATENUADAS, DIRECCIONAMIENTO DE GENES, TARGETING GENÉTICO, INMUNIZACIÓN, VACUNAS ACTIVADAS, VACUNAS
spellingShingle AGING POPULATION, LIVE ATTENUATED VACCINES, GENE TARGETING, IMMUNIZATION, INACTIVATED VACCINES, VACCINES
ENVEJECIMIENTO POBLACIONAL, VACUNAS VIVAS ATENUADAS, DIRECCIONAMIENTO DE GENES, TARGETING GENÉTICO, INMUNIZACIÓN, VACUNAS ACTIVADAS, VACUNAS
Chaves Rêgo, Leandro
Fierens, Pablo Ignacio
Gonçalves, Miguel
A new take on optimal vaccine prioritization: when age-based strategy is efficient?
topic_facet AGING POPULATION, LIVE ATTENUATED VACCINES, GENE TARGETING, IMMUNIZATION, INACTIVATED VACCINES, VACCINES
ENVEJECIMIENTO POBLACIONAL, VACUNAS VIVAS ATENUADAS, DIRECCIONAMIENTO DE GENES, TARGETING GENÉTICO, INMUNIZACIÓN, VACUNAS ACTIVADAS, VACUNAS
description "The rapid spread, high mortality rate, and hospital overcrowding made the SARS-CoV-2 virus a significant challenge for humanity. The emergent situation urgently called for investments in vaccine development as a critical measure to mitigate this issue. However, the financial costs and time required for vaccine development posed considerable obstacles to achieving comprehensive vaccination coverage. Therefore, understanding the most effective immunization strategy was paramount to contain the virus’s spread and optimize resource allocation in public policies. Age-based prioritization was applied in many regions, and one of the objectives of this work is to study under which circumstances such a strategy is efficient. Our results show that age-based vaccination is a poor strategy for disease eradication, although it has a fair performance in diminishing the number of deaths. Furthermore, other schemes, such as PageRank-based immunization, are much better options in general. We believe these results are of relevance, not only for the past SARS-CoV-2 pandemic, but also for future epidemic outbreaks".
format Artículo de publicación periódica
author Chaves Rêgo, Leandro
Fierens, Pablo Ignacio
Gonçalves, Miguel
author_facet Chaves Rêgo, Leandro
Fierens, Pablo Ignacio
Gonçalves, Miguel
author_sort Chaves Rêgo, Leandro
title A new take on optimal vaccine prioritization: when age-based strategy is efficient?
title_short A new take on optimal vaccine prioritization: when age-based strategy is efficient?
title_full A new take on optimal vaccine prioritization: when age-based strategy is efficient?
title_fullStr A new take on optimal vaccine prioritization: when age-based strategy is efficient?
title_full_unstemmed A new take on optimal vaccine prioritization: when age-based strategy is efficient?
title_sort new take on optimal vaccine prioritization: when age-based strategy is efficient?
publisher Springer Nature
publishDate 2026
url https://hdl.handle.net/20.500.14769/5266
https://doi.org/10.1007/s41060-026-01053-5
work_keys_str_mv AT chavesregoleandro anewtakeonoptimalvaccineprioritizationwhenagebasedstrategyisefficient
AT fierenspabloignacio anewtakeonoptimalvaccineprioritizationwhenagebasedstrategyisefficient
AT goncalvesmiguel anewtakeonoptimalvaccineprioritizationwhenagebasedstrategyisefficient
AT chavesregoleandro newtakeonoptimalvaccineprioritizationwhenagebasedstrategyisefficient
AT fierenspabloignacio newtakeonoptimalvaccineprioritizationwhenagebasedstrategyisefficient
AT goncalvesmiguel newtakeonoptimalvaccineprioritizationwhenagebasedstrategyisefficient
_version_ 1865139579247394816

Ejemplares similares