Online adjustable linear parameter-varying controller for artificial pancreas systems

The purpose of this article is to present a non-hybrid fully closed-loop controller for the Artificial Pancreas (AP) problem focused on long-term clinical trials and home-use applications. It includes physical activity (PA) and unannounced meals. The controller is based on a robust gain-scheduled al...

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Autores principales: Bianchi, Fernando D., Sánchez-Peña, Ricardo, Garelli, Fabricio
Formato: Artículo de publicación periódica
Lenguaje:Inglés
Publicado: Elsevier 2023
Materias:
PÁNCREAS
INSULINA
DIABETES TIPO 1
Acceso en línea:https://ri.itba.edu.ar/handle/20.500.14769/4203
Aporte de:
Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA) de Instituto Tecnológico de Buenos Aires (ITBA)
id I32-R138-20.500.14769-4203
record_format dspace
spelling I32-R138-20.500.14769-42032026-01-15T15:15:57Z Online adjustable linear parameter-varying controller for artificial pancreas systems Bianchi, Fernando D. Sánchez-Peña, Ricardo Garelli, Fabricio PÁNCREAS INSULINA DIABETES TIPO 1 The purpose of this article is to present a non-hybrid fully closed-loop controller for the Artificial Pancreas (AP) problem focused on long-term clinical trials and home-use applications. It includes physical activity (PA) and unannounced meals. The controller is based on a robust gain-scheduled algorithm with a Linear Parameter-Varying (LPV) structure. It takes into account the time-varying dynamics of the problem by adapting itself in real-time according to measured glucose levels, and allows online fine-tuning during tests and periodic evaluations without the need of a controller redesign. The proposed fully parameterized LPV control adds several features to our previous results, accounts for the main perturbations of the AP problem and simplifies its implementation. To help in the parameter fine-tuning, a methodology based on clinical information is proposed. In-silico tests show that the achieved performance is similar or better than our previous Automatic Regulation of Glucose (ARG) algorithm, tested in two clinical trials, with the addition of the features mentioned before. 2023-07-11T11:53:17Z 2023-07-11T11:53:17Z 2023-06 Artículo de publicación periódica F.D. Bianchi, R.S. Sánchez-Peña, Garelli F., Online adjustable linear parameter-varying controller for artificial pancreas systems, Biomedical Signal Processing and Control, Vol. 86, 2023. https://doi.org/10.1016/j.bspc.2023.105164 https://ri.itba.edu.ar/handle/20.500.14769/4203 en application/pdf Elsevier
institution Instituto Tecnológico de Buenos Aires (ITBA)
institution_str I-32
repository_str R-138
collection Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA)
language Inglés
topic PÁNCREAS
INSULINA
DIABETES TIPO 1
spellingShingle PÁNCREAS
INSULINA
DIABETES TIPO 1
Bianchi, Fernando D.
Sánchez-Peña, Ricardo
Garelli, Fabricio
Online adjustable linear parameter-varying controller for artificial pancreas systems
topic_facet PÁNCREAS
INSULINA
DIABETES TIPO 1
description The purpose of this article is to present a non-hybrid fully closed-loop controller for the Artificial Pancreas (AP) problem focused on long-term clinical trials and home-use applications. It includes physical activity (PA) and unannounced meals. The controller is based on a robust gain-scheduled algorithm with a Linear Parameter-Varying (LPV) structure. It takes into account the time-varying dynamics of the problem by adapting itself in real-time according to measured glucose levels, and allows online fine-tuning during tests and periodic evaluations without the need of a controller redesign. The proposed fully parameterized LPV control adds several features to our previous results, accounts for the main perturbations of the AP problem and simplifies its implementation. To help in the parameter fine-tuning, a methodology based on clinical information is proposed. In-silico tests show that the achieved performance is similar or better than our previous Automatic Regulation of Glucose (ARG) algorithm, tested in two clinical trials, with the addition of the features mentioned before.
format Artículo de publicación periódica
author Bianchi, Fernando D.
Sánchez-Peña, Ricardo
Garelli, Fabricio
author_facet Bianchi, Fernando D.
Sánchez-Peña, Ricardo
Garelli, Fabricio
author_sort Bianchi, Fernando D.
title Online adjustable linear parameter-varying controller for artificial pancreas systems
title_short Online adjustable linear parameter-varying controller for artificial pancreas systems
title_full Online adjustable linear parameter-varying controller for artificial pancreas systems
title_fullStr Online adjustable linear parameter-varying controller for artificial pancreas systems
title_full_unstemmed Online adjustable linear parameter-varying controller for artificial pancreas systems
title_sort online adjustable linear parameter-varying controller for artificial pancreas systems
publisher Elsevier
publishDate 2023
url https://ri.itba.edu.ar/handle/20.500.14769/4203
work_keys_str_mv AT bianchifernandod onlineadjustablelinearparametervaryingcontrollerforartificialpancreassystems
AT sanchezpenaricardo onlineadjustablelinearparametervaryingcontrollerforartificialpancreassystems
AT garellifabricio onlineadjustablelinearparametervaryingcontrollerforartificialpancreassystems
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