Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis

"Retinoblastoma is the most common intraocular tumor in childhood. Topotecan has been widely used as an antineoplastic agent for retinoblastoma treatment. Topotecan penetration into living tumorspheres is quantified using confocal microscopy. This fluorescent drug dyes the living tissue and it...

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Autores principales: Chan, Debora, Winter, Úrsula, Schaiquevich, Paula, Ramele, Rodrigo, Gambini, Juliana
Formato: Ponencias en Congresos acceptedVersion
Lenguaje:Inglés
Publicado: 2020
Materias:
RETINOBLASTOMA
PROCESAMIENTO DE IMAGENES
DIAGNOSTICO POR IMAGENES
TUMORES
ESTADISTICA
SEGMENTACION DE IMAGENES
Acceso en línea:http://ri.itba.edu.ar/handle/123456789/1923
Aporte de:
Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA) de Instituto Tecnológico de Buenos Aires (ITBA)
id I32-R138-123456789-1923
record_format dspace
spelling I32-R138-123456789-19232022-12-07T14:13:58Z Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis Chan, Debora Winter, Úrsula Schaiquevich, Paula Ramele, Rodrigo Gambini, Juliana RETINOBLASTOMA PROCESAMIENTO DE IMAGENES DIAGNOSTICO POR IMAGENES TUMORES ESTADISTICA SEGMENTACION DE IMAGENES "Retinoblastoma is the most common intraocular tumor in childhood. Topotecan has been widely used as an antineoplastic agent for retinoblastoma treatment. Topotecan penetration into living tumorspheres is quantified using confocal microscopy. This fluorescent drug dyes the living tissue and it can be recorded in a sequence of images over a period of time. The effective penetration of the drug depends on culture characteristics and requires a very specific timing. This penetration time is calculated empirically by an expert. The purpose of this work is to offer a statistical model to automatically estimate the penetration time of topotecan in the cell, based on the information obtained from a sequence of tumorsphere images." 2020-04-01T14:45:26Z 2020-04-01T14:45:26Z 2020 Ponencias en Congresos info:eu-repo/semantics/acceptedVersion 978-3030-30-647-2 1680-0737 http://ri.itba.edu.ar/handle/123456789/1923 en info:eu-repo/semantics/altIdentifier/doi/10.1007/978-3-030-30648-9_35 application/pdf
institution Instituto Tecnológico de Buenos Aires (ITBA)
institution_str I-32
repository_str R-138
collection Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA)
language Inglés
topic RETINOBLASTOMA
PROCESAMIENTO DE IMAGENES
DIAGNOSTICO POR IMAGENES
TUMORES
ESTADISTICA
SEGMENTACION DE IMAGENES
spellingShingle RETINOBLASTOMA
PROCESAMIENTO DE IMAGENES
DIAGNOSTICO POR IMAGENES
TUMORES
ESTADISTICA
SEGMENTACION DE IMAGENES
Chan, Debora
Winter, Úrsula
Schaiquevich, Paula
Ramele, Rodrigo
Gambini, Juliana
Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis
topic_facet RETINOBLASTOMA
PROCESAMIENTO DE IMAGENES
DIAGNOSTICO POR IMAGENES
TUMORES
ESTADISTICA
SEGMENTACION DE IMAGENES
description "Retinoblastoma is the most common intraocular tumor in childhood. Topotecan has been widely used as an antineoplastic agent for retinoblastoma treatment. Topotecan penetration into living tumorspheres is quantified using confocal microscopy. This fluorescent drug dyes the living tissue and it can be recorded in a sequence of images over a period of time. The effective penetration of the drug depends on culture characteristics and requires a very specific timing. This penetration time is calculated empirically by an expert. The purpose of this work is to offer a statistical model to automatically estimate the penetration time of topotecan in the cell, based on the information obtained from a sequence of tumorsphere images."
format Ponencias en Congresos
acceptedVersion
author Chan, Debora
Winter, Úrsula
Schaiquevich, Paula
Ramele, Rodrigo
Gambini, Juliana
author_facet Chan, Debora
Winter, Úrsula
Schaiquevich, Paula
Ramele, Rodrigo
Gambini, Juliana
author_sort Chan, Debora
title Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis
title_short Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis
title_full Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis
title_fullStr Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis
title_full_unstemmed Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis
title_sort time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis
publishDate 2020
url http://ri.itba.edu.ar/handle/123456789/1923
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AT winterursula timeestimationoftopotecanpenetrationinretinoblastomacellsthroughimagesequenceanalysis
AT schaiquevichpaula timeestimationoftopotecanpenetrationinretinoblastomacellsthroughimagesequenceanalysis
AT ramelerodrigo timeestimationoftopotecanpenetrationinretinoblastomacellsthroughimagesequenceanalysis
AT gambinijuliana timeestimationoftopotecanpenetrationinretinoblastomacellsthroughimagesequenceanalysis
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