Topotecan penetration assessment in retinoblastoma cells using Shannon entropy and coefficient of variation

"Retinoblastoma is a common intraocular tumor of childhood. One of the medications used as an antineoplastic agent for retinoblastoma treatment is topotecan. Its penetration into living tumorspheres is quantified using confocal microscopy. Topotecan is a fluorescent drug and it dyes the living...

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Autores principales: Howlin, Marcelo, Chan, Debora, Ramele, Rodrigo, Gambini, Juliana
Formato: Ponencias en Congresos acceptedVersion
Lenguaje:Inglés
Publicado: 2020
Materias:
TUMORES
ENTROPIA
RETINOBLASTOMA
DIAGNOSTICO POR IMAGENES
PROCESAMIENTO DE IMAGENES
ESTADISTICA
Acceso en línea:http://ri.itba.edu.ar/handle/123456789/1907
Aporte de:
Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA) de Instituto Tecnológico de Buenos Aires (ITBA)
id I32-R138-123456789-1907
record_format dspace
spelling I32-R138-123456789-19072022-12-07T14:13:49Z Topotecan penetration assessment in retinoblastoma cells using Shannon entropy and coefficient of variation Howlin, Marcelo Chan, Debora Ramele, Rodrigo Gambini, Juliana TUMORES ENTROPIA RETINOBLASTOMA DIAGNOSTICO POR IMAGENES PROCESAMIENTO DE IMAGENES ESTADISTICA "Retinoblastoma is a common intraocular tumor of childhood. One of the medications used as an antineoplastic agent for retinoblastoma treatment is topotecan. Its penetration into living tumorspheres is quantified using confocal microscopy. Topotecan is a fluorescent drug and it dyes the living tissue. Then, it is recorded in a sequence of images over a period of time. The effective penetration of the drug depends on culture characteristics and requires a very specific timing which is calculated empirically by an expert. The purpose of this work is to offer a model to automatically estimate and evaluate the penetration time of topotecan in a cell, based on the information obtained from a sequence of tumorsphere images and using Shannon entropy and coefficient of variation." 2020-03-18T13:49:45Z 2020-03-18T13:49:45Z 2019-09 Ponencias en Congresos info:eu-repo/semantics/acceptedVersion 978-1728-12-363-9 http://ri.itba.edu.ar/handle/123456789/1907 en info:eu-repo/semantics/altIdentifier/doi/10.1109/RPIC.2019.8882160 application/pdf
institution Instituto Tecnológico de Buenos Aires (ITBA)
institution_str I-32
repository_str R-138
collection Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA)
language Inglés
topic TUMORES
ENTROPIA
RETINOBLASTOMA
DIAGNOSTICO POR IMAGENES
PROCESAMIENTO DE IMAGENES
ESTADISTICA
spellingShingle TUMORES
ENTROPIA
RETINOBLASTOMA
DIAGNOSTICO POR IMAGENES
PROCESAMIENTO DE IMAGENES
ESTADISTICA
Howlin, Marcelo
Chan, Debora
Ramele, Rodrigo
Gambini, Juliana
Topotecan penetration assessment in retinoblastoma cells using Shannon entropy and coefficient of variation
topic_facet TUMORES
ENTROPIA
RETINOBLASTOMA
DIAGNOSTICO POR IMAGENES
PROCESAMIENTO DE IMAGENES
ESTADISTICA
description "Retinoblastoma is a common intraocular tumor of childhood. One of the medications used as an antineoplastic agent for retinoblastoma treatment is topotecan. Its penetration into living tumorspheres is quantified using confocal microscopy. Topotecan is a fluorescent drug and it dyes the living tissue. Then, it is recorded in a sequence of images over a period of time. The effective penetration of the drug depends on culture characteristics and requires a very specific timing which is calculated empirically by an expert. The purpose of this work is to offer a model to automatically estimate and evaluate the penetration time of topotecan in a cell, based on the information obtained from a sequence of tumorsphere images and using Shannon entropy and coefficient of variation."
format Ponencias en Congresos
acceptedVersion
author Howlin, Marcelo
Chan, Debora
Ramele, Rodrigo
Gambini, Juliana
author_facet Howlin, Marcelo
Chan, Debora
Ramele, Rodrigo
Gambini, Juliana
author_sort Howlin, Marcelo
title Topotecan penetration assessment in retinoblastoma cells using Shannon entropy and coefficient of variation
title_short Topotecan penetration assessment in retinoblastoma cells using Shannon entropy and coefficient of variation
title_full Topotecan penetration assessment in retinoblastoma cells using Shannon entropy and coefficient of variation
title_fullStr Topotecan penetration assessment in retinoblastoma cells using Shannon entropy and coefficient of variation
title_full_unstemmed Topotecan penetration assessment in retinoblastoma cells using Shannon entropy and coefficient of variation
title_sort topotecan penetration assessment in retinoblastoma cells using shannon entropy and coefficient of variation
publishDate 2020
url http://ri.itba.edu.ar/handle/123456789/1907
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AT chandebora topotecanpenetrationassessmentinretinoblastomacellsusingshannonentropyandcoefficientofvariation
AT ramelerodrigo topotecanpenetrationassessmentinretinoblastomacellsusingshannonentropyandcoefficientofvariation
AT gambinijuliana topotecanpenetrationassessmentinretinoblastomacellsusingshannonentropyandcoefficientofvariation
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