Unannounced meal analysis of the ARG algorithm

"One of the main challenges in automatic glycemic regulation in patients with type 1 diabetes (T1D) is to dispense with carbohydrate counting. In this context, we propose to equip a previously introduced switched Linear Quadratic Gaus-sian (LQG) controller—the so-called Automatic Regulation of...

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Autores principales: Fushimi, Emilia, Colmegna, Patricio, De Battista, Hernán, Garelli, Fabricio, Sánchez-Peña, Ricardo
Formato: Ponencias en Congresos acceptedVersion
Lenguaje:Inglés
Publicado: 2020
Materias:
DIABETES
ORGANOS ARTIFICIALES
PANCREAS
INSULINA
SISTEMAS DE CONTROL
Acceso en línea:http://ri.itba.edu.ar/handle/123456789/1854
Aporte de:
Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA) de Instituto Tecnológico de Buenos Aires (ITBA)
id I32-R138-123456789-1854
record_format dspace
spelling I32-R138-123456789-18542022-12-07T14:13:39Z Unannounced meal analysis of the ARG algorithm Fushimi, Emilia Colmegna, Patricio De Battista, Hernán Garelli, Fabricio Sánchez-Peña, Ricardo DIABETES ORGANOS ARTIFICIALES PANCREAS INSULINA SISTEMAS DE CONTROL "One of the main challenges in automatic glycemic regulation in patients with type 1 diabetes (T1D) is to dispense with carbohydrate counting. In this context, we propose to equip a previously introduced switched Linear Quadratic Gaus-sian (LQG) controller—the so-called Automatic Regulation of Glucose (ARG) algorithm—with an automatic switching signal generator (SSG). The ARG algorithm not only regulates the basal insulin infusion rate but also generates feedback insulin spikes at meal times, i.e., no open-loop insulin boluses are needed to mitigate postprandial glucose excursions. However, in its former version, it was required to announce the meal time. In this work, the performance of the ARG algorithm combined with the proposed SSG is assessed in silico with unannounced meals. In addition, the response of the SSG is estimated using clinical data obtained with the ARG algorithm in the first-ever artificial pancreas (AP) trials carried out in Latin America." 2020-01-06T17:31:14Z 2020-01-06T17:31:14Z 2019-07 Ponencias en Congresos info:eu-repo/semantics/acceptedVersion 0743-1619 http://ri.itba.edu.ar/handle/123456789/1854 en info:eu-repo/grantAgreement/ANPCyT/PICT/2014-2394/AR. Ciudad Autónoma de Buenos Aires info:eu-repo/grantAgreement/CONICET/PIP/112-201501-00837/AR. Ciudad Autónoma de Buenos Aires info:eu-repo/grantAgreement/Fundación Nuria/AR. Ciudad Autónoma de Buenos Aires info:eu-repo/grantAgreement/CDT/JDRF/2-APF-2019-737-A-N/US. Virginia info:eu-repo/grantAgreement/MINCIENCIAS/15-04/CO. Bogotá info:eu-repo/semantics/altIdentifier/doi/10.23919/acc.2019.8814719 application/pdf
institution Instituto Tecnológico de Buenos Aires (ITBA)
institution_str I-32
repository_str R-138
collection Repositorio Institucional Instituto Tecnológico de Buenos Aires (ITBA)
language Inglés
topic DIABETES
ORGANOS ARTIFICIALES
PANCREAS
INSULINA
SISTEMAS DE CONTROL
spellingShingle DIABETES
ORGANOS ARTIFICIALES
PANCREAS
INSULINA
SISTEMAS DE CONTROL
Fushimi, Emilia
Colmegna, Patricio
De Battista, Hernán
Garelli, Fabricio
Sánchez-Peña, Ricardo
Unannounced meal analysis of the ARG algorithm
topic_facet DIABETES
ORGANOS ARTIFICIALES
PANCREAS
INSULINA
SISTEMAS DE CONTROL
description "One of the main challenges in automatic glycemic regulation in patients with type 1 diabetes (T1D) is to dispense with carbohydrate counting. In this context, we propose to equip a previously introduced switched Linear Quadratic Gaus-sian (LQG) controller—the so-called Automatic Regulation of Glucose (ARG) algorithm—with an automatic switching signal generator (SSG). The ARG algorithm not only regulates the basal insulin infusion rate but also generates feedback insulin spikes at meal times, i.e., no open-loop insulin boluses are needed to mitigate postprandial glucose excursions. However, in its former version, it was required to announce the meal time. In this work, the performance of the ARG algorithm combined with the proposed SSG is assessed in silico with unannounced meals. In addition, the response of the SSG is estimated using clinical data obtained with the ARG algorithm in the first-ever artificial pancreas (AP) trials carried out in Latin America."
format Ponencias en Congresos
acceptedVersion
author Fushimi, Emilia
Colmegna, Patricio
De Battista, Hernán
Garelli, Fabricio
Sánchez-Peña, Ricardo
author_facet Fushimi, Emilia
Colmegna, Patricio
De Battista, Hernán
Garelli, Fabricio
Sánchez-Peña, Ricardo
author_sort Fushimi, Emilia
title Unannounced meal analysis of the ARG algorithm
title_short Unannounced meal analysis of the ARG algorithm
title_full Unannounced meal analysis of the ARG algorithm
title_fullStr Unannounced meal analysis of the ARG algorithm
title_full_unstemmed Unannounced meal analysis of the ARG algorithm
title_sort unannounced meal analysis of the arg algorithm
publishDate 2020
url http://ri.itba.edu.ar/handle/123456789/1854
work_keys_str_mv AT fushimiemilia unannouncedmealanalysisoftheargalgorithm
AT colmegnapatricio unannouncedmealanalysisoftheargalgorithm
AT debattistahernan unannouncedmealanalysisoftheargalgorithm
AT garellifabricio unannouncedmealanalysisoftheargalgorithm
AT sanchezpenaricardo unannouncedmealanalysisoftheargalgorithm
_version_ 1765661037598605312

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