T10 2010 1.indd
Much work has been carried out on non-enzymatic induced lipid peroxidation from different tissues of rat, but little information is available about this process in chinchilla. Studies were carried out to determine the levels of lipid peroxidation of homogenates isolated from liver, heart and kidney...
| Autores principales: | , , , |
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| Formato: | Artículo publishedVersion |
| Lenguaje: | Inglés |
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Universidad de Buenos Aires. Facultad de Ciencias Veterinarias.
2010
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| Acceso en línea: | http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_4986 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_4986.dir/4986.PDF |
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I28-R145-HWA_4986 |
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dspace |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
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R-145 |
| collection |
Repositorio Digital de la Universidad de Buenos Aires (UBA) |
| language |
Inglés |
| orig_language_str_mv |
eng |
| topic |
Corazón Riñón Hígado Peroxidación lipídica Chinchilla Rata Heart Kidney Liver Lipid peroxidation Chinchilla Rat |
| spellingShingle |
Corazón Riñón Hígado Peroxidación lipídica Chinchilla Rata Heart Kidney Liver Lipid peroxidation Chinchilla Rat Gutiérrez, A.M. Gavazza, M. Marmunti, M. Palacios, A. T10 2010 1.indd |
| topic_facet |
Corazón Riñón Hígado Peroxidación lipídica Chinchilla Rata Heart Kidney Liver Lipid peroxidation Chinchilla Rat |
| description |
Much work has been carried out on non-enzymatic induced lipid peroxidation from different tissues of rat, but little information is available about this process in chinchilla. Studies were carried out to determine the levels of lipid peroxidation of homogenates isolated from liver, heart and kidney of chinchilla and rat. Fatty acids located in total lipids of tissues studied were determined using gas chromatography and lipid peroxidation was evaluated by chemiluminescence assay. The lipid peroxidation process was more effective in rat liver and kidney homogenates than in chinchilla. In homogenates from liver and kidney of both species a signifi cant decrease of C20:4n6 and C22:6n3 acids were observed during lipoperoxidation. However, changes were not observed in the fatty acid profi les of heart. In the heart fatty acid profi le does not appear to be responsible for the different susceptibility to the lipid peroxidation. These results indicate that a low degree of fatty acid unsaturation in liver and kidney chinchilla, may confer advantage by decreasing their sensitivity to lipid peroxidation process of this specie. |
| format |
Artículo Artículo publishedVersion |
| author |
Gutiérrez, A.M. Gavazza, M. Marmunti, M. Palacios, A. |
| author_facet |
Gutiérrez, A.M. Gavazza, M. Marmunti, M. Palacios, A. |
| author_sort |
Gutiérrez, A.M. |
| title |
T10 2010 1.indd |
| title_short |
T10 2010 1.indd |
| title_full |
T10 2010 1.indd |
| title_fullStr |
T10 2010 1.indd |
| title_full_unstemmed |
T10 2010 1.indd |
| title_sort |
t10 2010 1.indd |
| publisher |
Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. |
| publishDate |
2010 |
| url |
http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_4986 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_4986.dir/4986.PDF |
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| _version_ |
1824359771416821760 |
| spelling |
I28-R145-HWA_49862024-11-05 T10 2010 1.indd Much work has been carried out on non-enzymatic induced lipid peroxidation from different tissues of rat, but little information is available about this process in chinchilla. Studies were carried out to determine the levels of lipid peroxidation of homogenates isolated from liver, heart and kidney of chinchilla and rat. Fatty acids located in total lipids of tissues studied were determined using gas chromatography and lipid peroxidation was evaluated by chemiluminescence assay. The lipid peroxidation process was more effective in rat liver and kidney homogenates than in chinchilla. In homogenates from liver and kidney of both species a signifi cant decrease of C20:4n6 and C22:6n3 acids were observed during lipoperoxidation. However, changes were not observed in the fatty acid profi les of heart. In the heart fatty acid profi le does not appear to be responsible for the different susceptibility to the lipid peroxidation. These results indicate that a low degree of fatty acid unsaturation in liver and kidney chinchilla, may confer advantage by decreasing their sensitivity to lipid peroxidation process of this specie. Fil: Gutiérrez, A.M. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Cátedra de Fisiología Animal. Buenos Aires, Argentina Fil: Gavazza, M. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Cátedra de Bioquímica. Buenos Aires, Argentina Fil: Marmunti, M. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Cátedra de Bioquímica. Buenos Aires, Argentina Fil: Palacios, A. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Cátedra de Bioquímica. Buenos Aires, Argentina Gutiérrez, A.M. Gavazza, M. Marmunti, M. Palacios, A. 2010 Peroxidación lipídica no enzimática en hígado, corazón y riñón de chinchilla y rata. Si bien se han realizado varios ensayos de peroxidación lipídica no enzimática en diferentes tejidos de rata, se tiene muy poca información acerca de este proceso en chinchillas. En el presente estudio se llevaron a cabo determinaciones comparativas acerca de los niveles de peroxidación lipídica en homogenatos aislados de hígado, corazón y riñón en chinchillas y ratas. Los ácidos grasos localizados en los lípidos totales de los tejidos estudiados fueron analizados utilizando cromatografía gaseosa y el proceso de peroxidación lipídica fue determinado mediante ensayos de quimioluminiscencia. El proceso de peroxidación lipídica fue más efectivo en homogenatos de hígado y riñón de rata que en los mismos tejidos aislados de chinchilla. Durante este proceso se observó que en homogenatos de hígado y riñón de ambas especies se produjo una disminución en el porcentaje de los ácidos grasos C20:4 n6 y C22:6 n3. Sin embargo estos cambios no fueron observados en el perfi l de ácidos grasos de corazón. En este órgano, el perfi l de ácidos grasos no parece ser responsable de su susceptibilidad a la peroxidación lipídica. Estos resultados indican que el bajo porcentaje de insaturación de hígado y riñón de chinchilla, podría conferir una ventaja debido a la disminución en la susceptibilidad al proceso de peroxidación lipídica en esta especie y esto podría representar una ventaja adaptativa frente a otras especies de roedores. application/pdf 1514-6634 (impreso) 1668-3498 (en línea) Corazón Riñón Hígado Peroxidación lipídica Chinchilla Rata Heart Kidney Liver Lipid peroxidation Chinchilla Rat eng Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ InVet, vol. 12, nº1 Non-enzymatic lipid peroxidation from liver, heart and kidney of chinchilla and rat Peroxidación lipídica no enzimática en hígado, corazón y riñón de chinchilla y rata. info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_4986 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_4986.dir/4986.PDF |